Eric I read your article and it intrigued me. I researched the hell out of naltrexone and I have a point I would like to bring up.
There are two schools of thought on using naltrexone. Correct me if I am wrong but you are recommending 25-50mgs of Naltrexone is this correct?
A lot of the research I am coming across recommends a lower dose and I will explain why.
From what I am finding 25-50mgs does not raise endorphin levels any more than 3-4.5mgs.
The benefit of the lower dose is...............
At 25-50 mgs the naltrexone blocks the opioid receptors from the increased endorphins for a periods of 7 half lives. The half life is 4 hours so that would be roughly 28 hours.
Again from my research, and this research is based on people using LDN (low dose naltrexone) for everything from autoimmune diseases to HIV and cancer with great results. Endorphins affect the endocrine system as well as the immune system and with LDN the receptors are blocked but only for roughly 4 hours. The 200-300% increase in endorphin production lasts over 24 hours however.
So I plan on using my naltrexone at 3mgs. It is actually a less is better type drug based on what I am finding. Both doses increase endorphins 200-300% but the lower dosage only blocks opioid receptors for 3-4 hours.