New Additions to the Primordial Performance Line-up

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What is Beta-Alanine?

Beta-alanine is a naturally occurring amino-acid in the human body that has been clinically proven to increase exercise performance and muscular endurance. Beta-Alanine is a nearly tasteless powder that easily dissolves and mixes in water. At the maximum recommended dose, a bottle of beta-alanine will last 31 days.

Beta-alanine allows the muscles to work more. This can lead to increased performance and improved body composition by allowing muscles to work at a higher volume, if you push them too.

How exactly does Beta-Alanine work?

If you are familiar with intense exercise, then you are familiar with the intense “burn” that accompanies the final reps of any given exercise. This burn is from the increased muscular acidity from the burning of ATP and glucose for energy. (2) As the muscles become more acidic they lose their ability to contract, they seize up, and the exercise comes to a halt.

Beta-alanine works by allowing the muscles to work harder and longer. Scientifically speaking, beta-alanine improves the intramyocellular buffer capacity by neutralizing the muscular acidity from lactic acid and hydrogen ions (H+) built up during intense exercise.

Research has established that beta-alanine works best at enhancing explosive “fast twitch” exercise performance during high intensity training, so be ready to push the envelope if you want to see the benefits of beta-alanine. (1-3) If your exercise program is lacking, or if you train like a wimp, then beta-alanine won’t help you.

How does Beta-Alanine buffer lactic acid? Is this safe?

Beta-alanine is known to increase carnosine concentrations in muscle tissue, and carnosine is known to act as a natural proton buffer in muscle tissue -- thus preventing intramyocellular acidosis. (1-3) Beta-alanine supplementation also appears to be the most efficient way to boost carnosine levels in muscle. In fact, oral supplementation of beta-alanine at 3.2 to 6.4gm/day has been shown increase carnosine concentration in human muscle tissue by 60-80%. (9,10)

There is evidence that persistent and long-term exposure to exercise may naturally increase carnosine concentrations in muscle, thus explaining why professional bodybuilders and elite level athletes maintain higher carnosine concentrations. (1) Therefore, increasing carnosine concentration in muscle tissue could be considered part of a natural adaptation or augmentation to resistance exercise.

How much can Beta-Alanine improve my performance?

Here is a brief review of several human studies on beta-alanine -

In 2008, researchers examined 30 days of beta-alanine supplementation (4.8 gm per day) on resistance exercise performance in eight resistance-trained men. (4) Their resistance exercise protocol consisted of 6 sets of 12 repetitions of the squat exercise at 70% of their one-repetition maximum (1-RM) with 1.5 minutes of rest between each set.

After 4 weeks, the beta-alanine group was able to perform 22% more total repetitions.

In another study, beta-alanine was given to trained sprinters for 4 weeks (2.4-3.6 gm per day). (12) In the beta-alanine group, knee extension power was significantly increased in each of the five bouts of 30 maximal contractions, whereas, in the placebo group, only the first two bouts were improved.

In a study performed on elderly individuals aging from 55-92 years, beta-alanine was supplemented at 2.4 gm per day. (13) After 90 days, physical working capacity was increased an astounding 28.6% in the beta-alanine group, while no change was found in the placebo group.

How does Beta-Alanine make Creatine & BCAA’s work better?

Yes, it appears that beta-alanine can enhance creatine’s ability to reduce body fat and build muscle in combination with resistance training. (7) Essentially, beta-alanine makes creatine work better.

This synergy was discovered by researchers in 2006, when 33 male subjects were randomly assigned to either a placebo, creatine, or creatine + beta-alanine group. After 10 weeks of weight training, the placebo group improved an average of 10lbs on bench press and squat strength, whereas both creatine and creatine + beta-alanine groups improved their average bench press by 25lbs and their squat strength by 55lbs. However, only the creatine + beta-alanine group had improvement in body composition [simultaneous muscle growth and fat reduction].

When beta-alanine was combined with BCAA’s it was found to reduce post workout muscle soreness from exercise, thus suggesting that beta-alanine and BCAA’s may have synergistic effects on enhancing muscle recovery. (8)

Note: Until further research is done, it’s unclear whether or not beta-alanine and creatine have synergistic effects on increasing muscular endurance when used together(5-6).

Does Beta-Alanine have any side effects?

Beta-alanine has been shown to be safe and effective for long-term use when used at the recommended dose. (3-8)

In some individuals, beta-alanine may cause a harmless “niacin-like” skin flush where the skin may become tingly and/or red for 15-20 minutes after consumption. (11) This symptom can be eliminated by spreading out each serving throughout the day, and/or consuming a serving of beta-alanine over a 60-90 minute period.



















What is Creapure?

Creapure® is ultra pure German manufactured creatine monohydrate. It is known as the purest, safest and most effective creatine in the world.

Only Creapure has been established to have a safety profile in accordance with internationally accepted guidelines and standards (FDA and EU) under GLP (Good Laboratory Practice) conditions. Because other creatine manufacturers use different manufacturing processes, and therefore have different purity profiles, only Creapure has this proven safety profile.

Typical analytical values for Creapure:

Creatine monohydrate: min. 99.95%
Creatinine: < 67 ppm (below the limit of detection)
Dicyandiamide (DCD): < 30 ppm
Dihydrotriazine (DHT): not detectable


How does creatine work?

For complete information on the performance enhancing benefits and research behind creatine monohydrate, please visit the official Creapure web site here.

Why buy our Creatine?

Because we sell the highest quality creatine available, at the lowest possible price.

Cheaper creatine can be found at other “bulk nutrition” stores but it’s not Creapure, unless it says its Creapure. These cheaper generic sources of creatine contain higher levels of dangerous impurities such as creatinine, dicyandiamide, and dihydrotriazine.

Remember, if it’s not Creapure®, it’s not proven.













What is IBCAA?

IBCAA’s are Instantized Branched Chain Amino Acids in a 2:1:1 ratio of L-leucine, L-isoleucine and L-valine. Unlike regular BCAA’s found at other bulk supplement stores, our Ajinopure IBCAA’s have been manufactured by Ajinomoto and are recognized as the purest, best tasting, and most water soluble BCAA’s available in the world.

Being that BCAA’s are essential amino acids, they must be supplied by dietary or supplemental sources, since the body cannot synthesize them. IBCAA’s are the perfect supplement to any beverage or protein shake. At the average recommended dose of 2 servings per day, a bottle of IBCAA will last 20 days.

Why would I want to use BCAA’s?

Next week, when I begin my low carbohydrate diet for fat loss, I’ll be using 3-4 servings of BCAA’s every day.

Why you ask?

Because BCAA’s help burn off body fat and preserve muscle very efficiently –especially if you are on a ketogenic or low calorie diet (also referred to as therapeutic starvation).

Essentially, starvation is when the body must feed upon itself – so it is up to you to direct the body to feed upon the fat, rather than the muscle if you want to sculpt out a chiseled physique. BCAA’s are quite possibly the most important tool for making this happen. The science is a little complex, but here is the basic idea –

1. The state of starvation can be created by either burning more calories than you consume, or consuming less calories than you burn. Either way, it’s called a calorie deficit, and you must be in a calorie deficit in order to burn off fat.

2. During a normal calorie deficit, blood glucose is used up as an energy source. When blood glucose gets too low, cortisol is released which causes the breakdown and conversion of muscle to glucose (This is bad for fat loss). (1)

3. BCAA supplementation helps prevent muscle breakdown by sparing glucose as an energy source and instead encouraging the release of ketones, which can be used as an alternative source of energy. (7)

4. Ketones are a byproduct of fat metabolism. When ketones are present, this means fat is being used as an energy source. Ketones also have the ability to prevent protein breakdown and catabolism of muscle tissue. (This is good for fat loss) (8-10)

The anti-catabolic fat loss effects of BCAA’s were clearly demonstrated in a 21-day study with a group of hikers trekking through the Peruvian Andes. (4) One group received 15gm/day of BCAA’s, while the other group received a placebo. At the end of the 21 days, the BCAA group actually gained lean muscle and lost more bodyfat than the placebo group which had a significant reduction in muscle mass and strength.

The researchers noted -

“From the differences in lean body mass one may conclude that on the whole the placebo group was catabolizing, whereas the BCAA group was synthesizing muscle tissue.”

Which group would you rather be in?

So there it is folks, the secret to fat loss. Encourage your body to use fat (ketones) for fuel, save the muscle from breakdown, and get ripped. Just know that if you want to get truly ripped, your calories (and preferably your carbohydrates) need to be low enough.

Will IBCAA help if I’m not dieting?

If you already consume 400-500 grams of animal based protein everyday you probably won’t notice additional benefits from BCAA supplementation since you probably get plenty of BCAA’s from your dietary protein – however, most normal humans have a hard time consuming this much protein each day – and this is where BCAA’s come in to fill the gap.

Can’t find time to grill up some protein? Or don’t want consume a sugar loaded protein bar?

This would be a perfect time to slam down a quick mix of IBCAA’s.

In fact researchers found that supplementing with ~15gm/day of BCAA’s increased protein retention just as much as a 200lb individual increasing total protein from 54gm to 90gms/day. (2-3) By increasing protein retention, BCAA’s can help retain and increase theavailability of circulating amino acids and promote muscle growth through stimulation of protein synthesis. (12-20) The L-Leucine in IBCAA is especially important for this purpose as it’s been shown to have a direct effect on protein synthesis through mTOR signaling and AMPK activation. (21-24)

An additional benefit of BCAA’s was demonstrated in a study with a group of runners. The first group received a milk protein mixture with 10 grams of BCAA’s. The second group received a milk protein mixture without BCAA’s. Both groups consumed the beverage 90 minutes before the run test. In the BCAA group, testosterone stayed the same during the exercise, and increased during the recovery period, while testosterone declined in the non-BCAA group. This shows an additive effect of BCAA’s when consumed with dietary protein.

Other research has shown that BCAA’s can enhance the anabolic (muscle building) effect of insulin. (11) The effect was summarized here by Maria et al –

“We can speculate that the amino acid-mediated [BCAA] enhancement of sensitivity and responsiveness of the tissues to the actions of insulin on suppressing proteolysis may be partly related to increased binding of insulin to its receptors, as well as to associated improvements in postreceptor function”

In laymen’s terms, BCAA’s could be considered a “growth optimizer” that help drive the amino acids into muscle tissue, encourage connection of individual amino acids into proteins than constitute the structural muscle – aka protein synthesis – and support further anabolic effect by supporting post exercise testosterone levels.

In summary, BCAA’s can offer the following benefits for muscle growth –

Promoting a positive protein balance
Increased muscle protein synthesis
Increase the post exercise testosterone : cortisol ratio
Increased insulin sensitivity


Are BCAA’s safe?

When used at the maximum recommended 20 gm daily dose, BCAA’s have been proven to be safe for long-term supplementation. (26-27)















Forty bucks for powered berries!?” - Anonymous Customer

True, $42.95 is a decent amount of money, but how does it compare to berries from the grocery store?

I had to find out, so I headed to the local grocery store to buy some organic berry’s -

Frozen Organic Strawberry’s ($4.15/283g bag)
Frozen Organic Raspberry’s ($4.55/284g bag)
Frozen Organic Blueberry’s ($4.55/227g bag)
Frozen Organic Cherry’s ($4.55/284g bag)
Organic Pomegranate ($3.99/each)
Frozen Organic Cranberry’s ($4.29/283g bag)


Then, I calculated the ratio’s of fruit found in Vitaberry® to figure how much it would cost to make a 60-serving bottle of Vitaberry with fresh or frozen fruit -

Cost of fresh/frozen organic fruit to make Vitaberry - $39.00

So really, Vitaberry is around the same price as what you’d pay at the grocery store except you don’t need to shop for berries, measure, portion and blend them. Instead, just take a scoop of Vitaberry with water, and bam, you’ve got a glass of glorious fruitiness.

And glorious it is – The fruits has been sourced from the best organic farms in the world, and freeze-dried to preserve every ounce of health promoting nutrients, and standardized to contain an impressive 2000 ORAC value for every 5gm serving. (1)

In case you’re wondering, ORAC stands for Oxygen Radical Absorbent Capacity. In laymen’s terms, the ORAC value is the total antioxidant capacity of all the phyto-constituents of a given sample. The higher the ORAC, the higher the anti-oxidant ability, and the better it can protect our DNA from damage by dangerous free-radicals that infiltrate our body every day.

According to the USDA, the average serving of fruit or vegetable has an ORAC rating of 400-500. This means that each serving of Vitaberry is equivalent to about 3-4 servings of fruits & vegetables in anti-oxidant power!

So why did we choose an organic blend?

Because organic fruits (and vegetables) have a higher nutritional value, meaning they have a higher concentration of vitamins, flavonoids, polyphenols, anthocyanins, chlorogenic acid and hundreds of other health supporting plant compounds. (6) Organic also means that its GMO free, sewage free, and pesticide free. From this prospective, you really pay for what you don’t want.

To put it simply; Organic is a major factor for supporting a long lasting, disease free, and cancer free life. (2-5)

How would I use Vitaberry? And when would I take it?

Vitaberry is a 100% natural nutrient loaded beverage, so it would be fine to use anytime of the day. Each serving contains only 3gm of naturally occurring sugar (15 calories), making it perfect for getting vital nutrients during a cutting or ketogenic diet where sugar and calories should be kept to a minimum.

How did we accomplish this?

By fortifying Vitaberry with two natural plant extracts known as stevia and lou han guo which are naturally sweet and virtually calorie free.

Plus Vitaberry packs a deliciously powerful fruit flavor making it a great formula for mixing with bulk supplement powders, such as BCAA’s, creatine monohydrate and beta-alanine.

Vitaberry is convenient, healthy, easy to mix and it tastes like a tropical punch. It's Mother Nature’s gift to the Primordial Man.









You can buy all these great Primordial Performance products here:

Beta Alanine

IBCAA

Creatine Creapure

VitaBerry

Remember to use the code: Sponsor10 to receive 10% off your order! :)
 
bslick69b

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sweet write ups trauma!
 
Trauma1

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Beta-Alanine:



References –

1. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition.
Kendrick IP, et al.
Amino Acids. 2008 May;34(4):547-54. Epub 2008 Jan 4.

2. Muscle metabolism during intense, heavy-resistance exercise.
PA Tesch, et al.
Eur J Appl Physiol Occup Physiol, Jan 1986; 55(4): 362-6.

3. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity.
Hill CA, et al.
Amino Acids (Vienna) 32: 225–233, 2007.

4. beta-Alanine and the Hormonal Response to Exercise.
J Hoffman, et al.
Int J Sports Med, December 1, 2008; 29(12): 952-8.

5. Effects of 28 days of beta-alanine and creatine monohydrate supplementation on aerobic power, ventilatory and lactate thresholds, and time to exhaustion.
RF Zoeller, et al.
Amino Acids, Sep 2007; 33(3): 505-10.

6. Effects of twenty-eight days of beta-alanine and creatine monohydrate supplementation on the physical working capacity at neuromuscular fatigue threshold.
Stout JR, et al.
J Strength Cond Res. 2006 Nov;20(4):928-31.

7. Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletes.
J Hoffman, et al.
Int J Sport Nutr Exerc Metab, August 1, 2006; 16(4): 430-46.

8. Attenuation of eccentric exercise-induced delayed onset muscle soreness (DOMS), muscle damage and oxidative stress by β-alanine (βA) and branched-chain amino acids (BCAA)
Masaru Furukawa, et al.
FASEB J, Mar 2008; 22: 685.1.

9. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis.
Harris RC, et al.
Amino Acids (Vienna) 30: 279–289, 2006.

10. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity.
Hill CA, et al.
Amino Acids (Vienna) 32: 225–233, 2007.

11. The plasma concentration-time profile of beta-alanine using a controlled-release formulation (Carnosyn®)
Roger C Harris, et al.
FASEB J, Mar 2008; 22: 701.9.

12. -Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters.
Wim Derave, et al.
J Appl Physiol, Nov 2007; 103: 1736 - 1743.

13. The effect of beta-alanine supplementation on neuromuscular fatigue in elderly (55-92 Years): a double-blind randomized study.
JR Stout, et a.
J Int Soc Sports Nutr, Jan 2008; 5: 21




IBCAA:


References


1. Metabolic effects of low cortisol during exercise in humans
Pedro Del Corral, et al.
J Appl Physiol, Mar 1998; 84: 939 - 947.

2. Branched-chain amino acid supplementation during bed rest: effect on recovery
T. P. Stein, et al.
J Appl Physiol, Apr 2003; 94: 1345 - 1352.

3. Effect of dietary protein on bed-rest-related changes in whole-body-protein synthesis
CA Stuart, et al.
Am. J. Clinical Nutrition, Sep 1990; 52: 509 - 514.

4. Branched-chain amino acid supplementation during trekking at high altitude. The effects on loss of body mass, body composition, and muscle power.
F Schena, et al.
Eur J Appl Physiol Occup Physiol, Jan 1992; 65(5): 394-8.

5. Acute response of net muscle protein balance reflects 24-h balance after exercise and amino acid ingestion
Kevin D. Tipton, et al.
Am J Physiol Endocrinol Metab, Jan 2003; 284: E76 - E89.

6. Essential amino acids and muscle protein recovery from resistance exercise
Elisabet Børsheim, Kevin D. Tipton, Steven E. Wolf, and Robert R. Wolfe
Am J Physiol Endocrinol Metab, Oct 2002; 283: E648 - E657

7. Partial oxidation of leucine in skeletal muscle.
TN Palmer, S Gossain, and MC Sugden
Biochem Mol Biol Int, Feb 1993; 29(2): 255-62.

8. Effect of ketone infusions on amino acid and nitrogen metabolism in man.
RS Sherwin, RG Hendler, and P Felig
J Clin Invest, June 1, 1975; 55(6): 1382-90.

9. 3-Hydroxybutyrate to conserve protein during therapeutic starvation.
Lancet, Feb 1983; 1(8321): 409.

10. The effect of ketone bodies on nitrogen metabolism in skeletal muscle.
JR Thompson and G Wu
Comp Biochem Physiol B, January 1, 1991; 100(2): 209-16.

11. Role of insulin and branched-chain amino acids in regulating protein metabolism during fasting.
Frexes-Steed M, et al.
Am J Physiol. 1990 Jun;258(6 Pt 1):E907-17.

12. Increase in anterior tibialis muscle protein synthesis in healthy man during mixed amino acid infusion: studies of incorporation of [1-13C]leucine.

13. The effect of amino acid infusion on leg protein turnover assessed by L-[15N]phenylalanine and L-[1-13C]leucine exchange.
WM Bennet, et al.
Eur J Clin Invest, Feb 1990; 20(1): 41-50.

14. Euglycemic hyperinsulinemia augments amino acid uptake by human leg tissues during hyperaminoacidemia
W. M. Bennet, et al.
Am J Physiol Endocrinol Metab, Aug 1990; 259: E185 - E194

15. Signaling Pathways and Molecular Mechanisms through which Branched-Chain Amino Acids Mediate Translational Control of Protein Synthesis.
Scot R. Kimball et al.
J. Nutr., Jan 2006; 136: 227S - 231S.

16. Effects of branched-chain amino acids on protein turnover.
ME May and MG Buse
Diabetes Metab Rev, May 1989; 5(3): 227-45.

17. Amino acid ingestion improves muscle protein synthesis in the young and elderly.
Padden-Jones D, et al.
Am J Physiol Endocrinol Metab. 2004 Mar;286(3):E321-8.

18. Effects of prolonged administration of branched-chain amino acids on body composition and physical fitness
N Candeloro, et al.
Minerva Endocrinol, Dec 1995; 20(4): 217-23

19. Postexercise net protein synthesis in human muscle from orally administered amino acids
Kevin D. et al
Am J Physiol Endocrinol Metab, Apr 1999; 276: E628 - E634.

20. Contractile and nutritional regulation of human muscle growth.
Rasmussen BB, et al.
Exerc Sport Sci Rev. 2003 Jul;31(3):127-31.

21. Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia.
Rieu, Isabelle. et al
J. Physiol. 2006;575;305-15.

22. Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise.
Norton LE and Layman DK.
J Nutr. 2006; 136(2):533S-537S.

23. Leucine and protein synthesis: mTOR and beyond. Nutrition Reviews.
Stipanuk, et al.
2007;Mar;Vol. 65, No. 3:122-9.

24. Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation.
Anthony, et al.
J Nutr 130: 139-145, 2000.

25. Changes in the exercise-induced hormone response to branched chain amino acid administration.
G Carli, et al.
Eur J Appl Physiol Occup Physiol, Jan 1992; 64(3): 272-7.

26. Interrelationship between Physical Activity and Branched-Chain Amino Acids
Michael Gleeson et al
J. Nutr., Jun 2005; 135: 1591S - 1595S.

27. An approach to defining the upper safe limits of amino acid intake.
Pencharz PB, et al.
J Nutr. 2008 Oct;138(10):1996S-2002S.




Vitaberry:

References

1. Hot air and freeze-drying of high-value foods: a review
C.Ratti et al.
Journal of food engineering (2001) 311-319

2. Nijveldt et al. Am J Clin Nutr 2001

3. Organic food in cancer therapy.
B Bishop
Nutr Health, January 1, 1988; 6(2): 105-9.4

4. Ames, B. N., Gold, L. S. & Willet, W. C. (1995) The causes and prevention of
cancer. Proc. Natl. Acad. Sci. USA. 92: 5258-5265

5. Ames, B. N., Shigenaga, M. K. & Hagen, T. M. (1993) Oxidants, antioxidants,
and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA. 90: 7915-
7922.

6. Caris-Veyrat et al. J Agric Food Chem 2004​
 
Trauma1

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If any of you have specific questions about these product, please feel free to ask away.
 
somewhatgifted

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If i was ever to be a rep... PP i choose you.
 
bolt10

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Wow thats some real fundamental and nice stuff right there. Will nutra be getting this stuff or is it just gonna be off the PP site?
 
Trauma1

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Wow thats some real fundamental and nice stuff right there. Will nutra be getting this stuff or is it just gonna be off the PP site?
I'll be inquiring about that, so i'll get back to you. I agree though, great fundamental additions indeed. :)
 
Flyboy

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Nice stuff indeed....

I'll probably pick up the creapure, IBCAA and BA at some point.... I know the vitaberry looks good but I think certain other products have my anti-oxidant bases covered at a lower cost. The others look great though.
 
Eric Potratz

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Nice stuff indeed....

I'll probably pick up the creapure, IBCAA and BA at some point.... I know the vitaberry looks good but I think certain other products have my anti-oxidant bases covered at a lower cost. The others look great though.
Would it be more impressive if we increased the ORAC value?

-Eric
 
Frank Reynolds

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You guys have a solid, well rounded line up. I like the fact that you made these new additions.. These are all products that really should be staples for anyone, rather then all the "snake oil" type supps most people use, looking for a miracle.

WHats the good word on those larger BCAA?

Vitaberry- Is one scoop daily enough?

Ps. Not sure if you already know this, but NOW foods has a product called VitaBerry
 
Last edited:
Eric Potratz

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You guys have a solid, well rounded line up. I like the fact that you made these new additions.. These are all products that really should be staples for anyone, rather then all the "snake oil" type supps most people use, looking for a miracle.

WHats the good word on those larger BCAA?

Vitaberry- Is one scoop daily enough?

Ps. Not sure if you already know this, but NOW foods has a product called VitaBerry
The kilo sizes are coming next week hopefully.

The Vitaberry is taken as desired. I personally take 1-2 scoops everyday when i take my BCAA's.

-Eric
 
bolt10

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The kilo sizes are coming next week hopefully.

The Vitaberry is taken as desired. I personally take 1-2 scoops everyday when i take my BCAA's.

-Eric
Yay for kilos! I like these additions tho(already stated this) i just think it makes it easier for ppl who like ur company and they can support u through getting pretty much anything they need(i kno i like to buy things from some companies over bulk retailers just to help show support)
 
mixedup

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you know vitaberry may be just what I need i have been making a tea using frozen blueberrys and hot water. this seems easier
 

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I have a question regarding the beta alanine. I was thinking about picking some of this up, are there any other side effects besides what is listed in this write up? I ran it once in the past (obviously a different brand). What I took also had L histidine in it, I dosed it at 3200mgs of beta and 300mg of L histidine. I enjoyed using it but had some issues w/ cramps. It once got so bad after I did a set of hanging straight leg raises I actually had to leave the gym because my lower abdomen cramped up. It was almost like it was stuck flexed and was very painful. I thought i tore something but it went away after about 15 mins. I once read something Dr. D posted about a possible side effect that might have related to this w/ beta alanine but I cant seem to be able to dig it up. I really would like to run it again because it worked well for me but would like to figure this out first. Any thoughts?
 
Eric Potratz

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I have a question regarding the beta alanine. I was thinking about picking some of this up, are there any other side effects besides what is listed in this write up? I ran it once in the past (obviously a different brand). What I took also had L histidine in it, I dosed it at 3200mgs of beta and 300mg of L histidine. I enjoyed using it but had some issues w/ cramps. It once got so bad after I did a set of hanging straight leg raises I actually had to leave the gym because my lower abdomen cramped up. It was almost like it was stuck flexed and was very painful. I thought i tore something but it went away after about 15 mins. I once read something Dr. D posted about a possible side effect that might have related to this w/ beta alanine but I cant seem to be able to dig it up. I really would like to run it again because it worked well for me but would like to figure this out first. Any thoughts?
I never ran across anything like that in the literature with beta-alanine and since Ive started it myself I havnt noticed that either.

I would look into some electrolyte supplementation for your cramping… maybe potassium and magnesium will do the trick for you.

-Eric
 
Trauma1

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I have a question regarding the beta alanine. I was thinking about picking some of this up, are there any other side effects besides what is listed in this write up? I ran it once in the past (obviously a different brand). What I took also had L histidine in it, I dosed it at 3200mgs of beta and 300mg of L histidine. I enjoyed using it but had some issues w/ cramps. It once got so bad after I did a set of hanging straight leg raises I actually had to leave the gym because my lower abdomen cramped up. It was almost like it was stuck flexed and was very painful. I thought i tore something but it went away after about 15 mins. I once read something Dr. D posted about a possible side effect that might have related to this w/ beta alanine but I cant seem to be able to dig it up. I really would like to run it again because it worked well for me but would like to figure this out first. Any thoughts?
Muscle cramping like you've described can occur though many different pathways. It can be a collective or specific electrolyte imbalance (mainly sodium, potassium, magnessium, or calcium), or it can be a problem with the sodium-potassium ATPase pump, or the calcium channel pump. Calcium is required for muscular contraction, and magnesium is required as well for muscular relaxation.

A prime example of a problem with a calcium channel pump would be a spastic muscle, or "charlie horse." If calcium can't be effectively pumped out of the muscle via the channel, the cell temporarily malfunctions, and the muscle is basically stuck in a contracted state. This is VERY painful, and can last different durations depending on the underlying circumstances.

Problems with the sodium-potassium ATPase pump can lead to an unequal intra/extra cellular balance of said electrolytes, as well as dramatic changes in osmotic fluid shifts. This means that more osmotically active particles (mainly sodium) can be contained inside the cell than outside the cell. This causes more fluid to enter the cell due to a significant osmotic pull. The extra fluid then becomes trapped in cells (due to a higer concentration of osmotically active particles in the cells), and causes them to swell. This is commonly what you hear bodybuilders complain about with "Painful Muscle Pumps." Adding more osmotically charged particles to your extracellular fluid compartments (by adding sodium or electrolytes) will shift some of the fluids back to the extracellular compartment to reinstate fluid shift homeostasis. The end result is alleviating this "Painful Pump." This can be easier said than done many times however. Some interventions can help (Taurine, electrolytes, time), but each individual case will respond differently depending on a multitude of factors.

Excessive muscle use/damage can also bring upon a state of elevated lactic acidosis. Buffering systems put into place by our body attempt neutralize this issue via either chemical, respiratory, or renal (kidney) involvement. Beta-Alanine adds to the chemical buffer system to neutralize the issue, and allow muscle functions to continue when they would normally cease. Failure of these compensatory mechanisms (for many different reasons) can lead to cellular pump problems, and hypersensitivity issues, and most certainly metabolic acidosis issues. Thus, it can also contribute to muscle cramping issues.

In other words, trying to pinpoint the exact etiology for a given episode of muscle cramping can be challenging in ways. The human body is SOOO complex, that pinpointing some things is almost impossible at times. As long as you maintain sufficient electrolyte intake, and don't overstress specific muscle groups, any associated issues should be at least limited in nature.

Now that i'm done with my rant :p, i myself haven't read of these issues specifically with beta-alanine ingestion. I'll look into it myself, but i honestly don't think that beta-alanine was the specific cause of your complaints. I'll research it some more though, and I'll get back to you all with my findings.


Here's a few interesting things to look over in your spare time as well. :)


Sodium-Potassium Exchange Pump


Magnesium and cramps
 
Iron Lungz

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Na+K+ Pump.

I agree with T1, read up on the links that he provided.
 

crazilyfter42

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Thanks for the response and the links they were informative. Im actually pretty well versed biologically, Ive had my fair share of scientific courses in college. I understand the issues regarding why cramps occur. Thats pretty much why this really bothered me. The cramps occured more often and were different than what I normally experienced throughout the years I have worked out. The issues also ceased once I stopped the supplemention. I really enjoyed the results I saw from beta alanine though. I got stronger and noticed a definate improvement in body composition. I figured the cramping had something to do with the way it effects lactic acid but thats just a guess. If you find any information regarding this please pass it along to me and thanks for looking. I will probably end up picking this up it worked so well for me that I def feel its worth it, especially at that price!
 
Trauma1

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Thanks for the response and the links they were informative. Im actually pretty well versed biologically, Ive had my fair share of scientific courses in college. I understand the issues regarding why cramps occur. Thats pretty much why this really bothered me. The cramps occured more often and were different than what I normally experienced throughout the years I have worked out. The issues also ceased once I stopped the supplemention. I really enjoyed the results I saw from beta alanine though. I got stronger and noticed a definate improvement in body composition. I figured the cramping had something to do with the way it effects lactic acid but thats just a guess. If you find any information regarding this please pass it along to me and thanks for looking. I will probably end up picking this up it worked so well for me that I def feel its worth it, especially at that price!
No problem. I'll be looking into it for sure to see what i can dig up.

I agree, it is a hell of a deal. :D
 

Motox

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I picked up the B.A, Creatine and sustain alpha. Pp is in my opinion the top company out there supplement wise I will be a lifetime customer for sure. Trauma you are a smart guy its nice to see you on here, I cant wait to see what comes next fro PP because I know that it WILL work!
 
Trauma1

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I picked up the B.A, Creatine and sustain alpha. Pp is in my opinion the top company out there supplement wise I will be a lifetime customer for sure. Trauma you are a smart guy its nice to see you on here, I cant wait to see what comes next fro PP because I know that it WILL work!
Thanks, motox! I really appreciate the kind words buddy, and thank you for your continued support of Pp! It's great to be part of team Primordial for sure. The primordial product line is really growing nicely, and it demonstrates an integrated approach of both fundamental and innovative proportions to supplementation.

2009 will be a great year for Primordial Performance! :cheers:
 

Motox

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No prob PP products do the talking! I want to be buried with a bottle of sustain alpha next to me.

P.s- The sex drive on sustain is as usual, Insane! My poor poor gilfriend
 
bolt10

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Just picked up some of your Beta Alanine to show some support :)
 

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