SERMs and Medication reactions...
- 03-04-2008, 06:45 PM
- 03-05-2008, 05:47 PM
03-05-2008, 06:19 PM
03-05-2008, 07:48 PM
03-05-2008, 07:49 PM
Drugs that decrease renal calcium excretion, eg, thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. There is a known interaction between antiestrogenic compounds of the triphenylethylene derivative class and coumarin-type anticoagulants (eg, warfarin), leading to an increased prothrombin time. When concomitant use of anticoagulants with FARESTON is necessary, careful monitoring of the prothrombin time is recommended.
Cytochrome P450 3A4 enzyme inducers, such as phenobarbital, phenytoin, and carbamazepine increase the rate of toremifene metabolism, lowering the steady-state concentration in serum. Metabolism of toremifene may be inhibited by drugs known to inhibit the CYP3A4-6 enzymes. Examples of such drugs are ketoconazole and similar antimycotics as well as erythromycin and similar macrolides. This interaction has not been studied and its clinical relevance is uncertain.
can anyone put that in layman's terms?
03-07-2008, 07:09 AM
03-08-2008, 07:13 PM
03-08-2008, 08:23 PM
03-08-2008, 10:02 PM
thanks...now i do take a minocycline ( acne medicine, its solodyn )
that means that i cannot take the torem and the antibiotic right? how long would i have to wait to stop the medicine before i start the PCT
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