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Eagleman003
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I did a cycle of 1ad/4ad for 30 days at mild doses and gained a good 10-12 pounds. I started taking Nolvadex @ 40/40/20/20, some left over 6-oxo @ 500/200/200, activate pills and cycle support by AI. I am about at the end of my first week and I feel as though I have shrunk a good deal. My arm measurements went down 1/8 of an inch and my chest and shoulders look less full. My calories have been at around or above maintance for my new BW and i added a tiny bit of cardio postworkout for 20 min at around 60% intensity 3 days a week. I came to the conclusion that I am either imagining this stuff or the claim that nolvadex reduces gains is sorta true. I found this information when i did a search:
Nolvadex reduces IGF-1 production, which diminish the hypertrophic response. This IGF lowering effect is in fact one of the reasons for the use of tamoxifen to help with breast cancer. ER-negative breast cancer cells are responsive to IGF-1 (IGF-1 makes them grow), the fact that tamoxifen lowers circulating IGF-1 is the reason for its use as an anti-cancer medicine (Pollack et al. 1990)
Nolvadex (and other anti-E/anti-A) reduces bloating... while bloating isn't muscle mass, it can contribute to stimulating growth via 2 pathways: a) increasing intramuscular pressure (also called cell volumization) has been shown to increase protein synthesis (Stoll et al. 1992) and decrease muscle breakdown (Hallbrucker et al. 1990, Hallbrucker et al. 1991, vom Dahl et al. 1991, Häussinger et al. 1990, vom Dahl et al. 1995), whereas a ''flat'' muscle leads to a catabolic state ... to quote Haussinger et al (1996) ''cell shrinkage inhibits, whereas cell swelling stimulates, protein synthesis ''.
''Bloating'' improves joint stability and force levers which allows you to lift more weight either by desentisizing the protective mechanisms of the muscle (the more stable joint makes the CNS ''believes'' that it's safe to produce more force) or by improved leverage. This is why several powerlifters actually ''bloat'' on purpose prior to a contest (after they weight in). The capacity to lift more weight = more potential growth stimulation.
Estrogen is needed, to some extent, for optimal muscle growth.
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I feel that the loss in strength I have recieved and the lose in BW is due to less bloating and the fact that Nolvadex reduces the aiblity to uptake glyocgen and water into the muscle cells which makes me seem less full all of the time. How much strength do you guys genereally lose coming off of a PH cycle? Not a AAS cycle.
Do you think after I am done with my PCT I will fill back up with glycogen and look better? Also, I was planning on doing around 3 weeks or so (23-25) days of nolvadex and not 4 weeks considering the dosages I used were mild to light and this was a PH cycle that lasted 30 days.
Any thoughts guys?
Nolvadex reduces IGF-1 production, which diminish the hypertrophic response. This IGF lowering effect is in fact one of the reasons for the use of tamoxifen to help with breast cancer. ER-negative breast cancer cells are responsive to IGF-1 (IGF-1 makes them grow), the fact that tamoxifen lowers circulating IGF-1 is the reason for its use as an anti-cancer medicine (Pollack et al. 1990)
Nolvadex (and other anti-E/anti-A) reduces bloating... while bloating isn't muscle mass, it can contribute to stimulating growth via 2 pathways: a) increasing intramuscular pressure (also called cell volumization) has been shown to increase protein synthesis (Stoll et al. 1992) and decrease muscle breakdown (Hallbrucker et al. 1990, Hallbrucker et al. 1991, vom Dahl et al. 1991, Häussinger et al. 1990, vom Dahl et al. 1995), whereas a ''flat'' muscle leads to a catabolic state ... to quote Haussinger et al (1996) ''cell shrinkage inhibits, whereas cell swelling stimulates, protein synthesis ''.
''Bloating'' improves joint stability and force levers which allows you to lift more weight either by desentisizing the protective mechanisms of the muscle (the more stable joint makes the CNS ''believes'' that it's safe to produce more force) or by improved leverage. This is why several powerlifters actually ''bloat'' on purpose prior to a contest (after they weight in). The capacity to lift more weight = more potential growth stimulation.
Estrogen is needed, to some extent, for optimal muscle growth.
---------------------------
I feel that the loss in strength I have recieved and the lose in BW is due to less bloating and the fact that Nolvadex reduces the aiblity to uptake glyocgen and water into the muscle cells which makes me seem less full all of the time. How much strength do you guys genereally lose coming off of a PH cycle? Not a AAS cycle.
Do you think after I am done with my PCT I will fill back up with glycogen and look better? Also, I was planning on doing around 3 weeks or so (23-25) days of nolvadex and not 4 weeks considering the dosages I used were mild to light and this was a PH cycle that lasted 30 days.
Any thoughts guys?
