Toremifene: an evaluation of its safety profile.

  1. New Member
    bigred869's Avatar
    5'10"  155 lbs.
    Join Date
    Feb 2005
    Rep Power
    Lv. Percent

    Toremifene: an evaluation of its safety profile.

    Harvey HA, Kimura M, Hajba A.

    Division of Hematology/Oncology, Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA.

    Toremifene has been in clinical use for 8 years for the treatment of advanced hormone-sensitive breast cancer and the adjuvant treatment of early breast cancer. More than 350,000 patient treatment years have accumulated, sufficient to allow evaluation of its longer-term safety profile in comparison with tamoxifen and, where possible, with raloxifene and aromatase inhibitors. We reviewed all preclinical and clinical safety data from 1978 to 2004 and comparative clinical safety data between October 1995 and the end of 2004. Secondary endometrial cancer incidence was lower with toremifene than with tamoxifen and was similar to that with raloxifene. It is speculated that toremifene may unmask existing endometrial tumors rather than induce new events. The risk of stroke, pulmonary embolism, and cataract may be lower with toremifene than with tamoxifen and the risk of pulmonary embolism and deep vein thrombosis lower than with raloxifene. Beneficial estrogen agonistic effects were equivalent to those of tamoxifen regarding bone mineral density and superior regarding lipid profiles.

    PMID: 16289904 [PubMed - indexed for MEDLINE]

  2. Elite Member
    bioman's Avatar
    5'10"  180 lbs.
    Join Date
    Sep 2003
    Rep Power
    Lv. Percent
    Achievements Activity ProActivity AuthorityPosting ProPosting Authority

    Good article. I know Torem treats me far better than Tamox. Tamox ruins my skin by giving me little red bumps on my forehead and body..seems like a sign of oxidative damage if I had to guess. That and Torem works 10X faster and better for PCT purposes IMO.

Similar Forum Threads

  1. Just seen an endo, looking for evaluation of prescription
    By newttt in forum Male Anti-Aging Medicine
    Replies: 8
    Last Post: 11-16-2011, 10:24 PM
  2. Replies: 24
    Last Post: 11-29-2006, 02:29 AM
  3. An Analysis of the Relative Safety of Ephedra
    By Sheesh in forum Supplements
    Replies: 3
    Last Post: 03-05-2003, 06:51 PM
  4. Adipose Tissue: What is it & How to get rid of it
    By YellowJacket in forum Exercise Science
    Replies: 0
    Last Post: 03-03-2003, 09:29 PM
  5. The Sets and Reps of it
    By Gray Fox in forum Exercise Science
    Replies: 3
    Last Post: 02-21-2003, 11:39 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
Log in