Hmm ill have to take a look
1,4,6 Androstatriene-Dione-
ATD is a supplement that gained huge exposure in numerous OTC PCT products over the past several years. It is a suicidal inhibitor of the aromatase enzyme, meaning that once the drug has been discontinued enzyme levels slowly return to baseline. Suicidal inhibitors are often preferred because there is no “rebound” in estrogens after coming off.
Scientific data on ATD shows it to be an effective anti estrogen and also would lead you to believe it produces immense increases in testosterone, however other data shows it produces a steroidal metabolite known as 1,4,6 Testosterone. The production of this weak androgen (about ⅓ the potency of testosterone) causes false readings on testosterone serum tests.ATD has huge amounts of anecdotal feedback claiming it markedly reduces sex drive, but it was largely speculated that this was due to a substantial decrease in estrogen (low or high estrogen in males will reduce libido). Scientific literature has pointed us in another direction and shown that ATD is actually anti-androgenic (the complete opposite of what we would want).
The claims that this is great in PCT are nil when the data has been observed. It will reduce estrogen, but also occupy the androgen receptor and not allow testosterone to bind. The 1,4,6 testosterone metabolite would also theoretically produce HPTA suppression if the dose is significant.
