SERMs and potential blod clots and stroke.

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  1. steakboy
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    SERMs and potential blod clots and stroke.


    I'm going to bring up an interesting question that's been spinning around in my head ever since i went to a urologist to check if the soldiers are still fit for duty.

    After speaking with the doc he says the constant cycling of on and off and your testes rebounding so often is detrimental to the long term of your sperm count. eventually leading to possible infertility. He said quote,"they will rebound only so many times". He pointed me to the method of HRT which seems to be a bit safer. He also seemed to be a strong proponent of testosterone gels for delivery rather than injections.

    Additionally he almost feinted when i told him i used SERMs after a cycle. He said that there's a rather fatal side effect with blood clots and strokes. This isn't talked about much on the boards or... well anywhere for that matter. I had to specifically look up this problem and it seems that the people who use it for what the drug is intended (fertility) are having issues with this.

    So on to my question... there has to be a safer way. I've used DIM coming off mdrol before with moderate success. is there a way to cover MOST of the bases without resorting to dangerous substances like SERMs?


  2. That's why I try to always recommend a low dose SERM, just to try and negate some of the toxicity levels of SERMs.

    The low dose SERM needs to be accompanied by an OTC PCT. I know Primordial makes quality supplements and I have the most experience with their line. The Testosterone Replacement Stack is going to work great with a low dose SERM.

    If you want to only run the TRS, then it will suffice for shorter cycle. Anything over 6 weeks it may not be as effective unless you run it longer. 8 weeks instead of 4, but you'd need two of them. And that's just flat out too expensive.
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  3. Quote Originally Posted by tbonesteakboy View Post
    I'm going to bring up an interesting question that's been spinning around in my head ever since i went to a urologist to check if the soldiers are still fit for duty.

    After speaking with the doc he says the constant cycling of on and off and your testes rebounding so often is detrimental to the long term of your sperm count. eventually leading to possible infertility. He said quote,"they will rebound only so many times". He pointed me to the method of HRT which seems to be a bit safer. He also seemed to be a strong proponent of testosterone gels for delivery rather than injections.

    Additionally he almost feinted when i told him i used SERMs after a cycle. He said that there's a rather fatal side effect with blood clots and strokes. This isn't talked about much on the boards or... well anywhere for that matter. I had to specifically look up this problem and it seems that the people who use it for what the drug is intended (fertility) are having issues with this.

    So on to my question... there has to be a safer way. I've used DIM coming off mdrol before with moderate success. is there a way to cover MOST of the bases without resorting to dangerous substances like SERMs?

    Personally if you are looking for the best all around PCT that you can have without going the SERM route, you should consider the TRS.
    Just inject.
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  4. steakboy
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    Says here that AI's aren't anywhere near as bad. that in conjuction with a smart use of hcg would be a good way to go.

    I'm thinking of running a nice long 12 weeker here soon and i'll be a little smarter about my PCT. to hell with these SERMs man... why does everybody recommend using them if they're this bad?

  5. Quote Originally Posted by tbonesteakboy View Post
    Says here that AI's aren't anywhere near as bad. that in conjuction with a smart use of hcg would be a good way to go.

    I'm thinking of running a nice long 12 weeker here soon and i'll be a little smarter about my PCT. to hell with these SERMs man... why does everybody recommend using them if they're this bad?
    Because it's what everyone does. So people usually just follow suit. Some intelligent minds develop other products, but because the big boys want to keep their hierarchy intact, they just keep putting OTC pct down.
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  6. Quote Originally Posted by tbonesteakboy View Post
    Says here that AI's aren't anywhere near as bad. that in conjuction with a smart use of hcg would be a good way to go.

    I'm thinking of running a nice long 12 weeker here soon and i'll be a little smarter about my PCT. to hell with these SERMs man... why does everybody recommend using them if they're this bad?
    hCG is a very smart choice for a 12 week cycle, and will surely help with your recovery. Eric has an article on hCG usage as well.

    Personally, on a 12 week cycle, I would still use a SERM, but I would do it in a lower dosage than necessary since I would be running the TRS.
    Just inject.
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  7. steakboy
    steakboy's Avatar

    I'm glad PP is out to help. you guys have a lot of real information and scientific facts to back your **** rather than all this bro-science everybody on the boards uses.

    paying three times the price for a proper PCT is a little tough to swallow BUT when it comes down to if i'm going to get a blood clot and die or not, the choice really isn't much of a choice anymore, is it?

    *lol'ing at the fact my PCT is going to cost more than my gear.
    Last edited by steakboy; 01-28-2011 at 04:50 PM. Reason: lulz

  8. Serms is way too pushed imo. I will admit, im toying with the idea of using a serm, but the idea of being able to do it naturally interests me more. I think for my next prohormone run ill only be using ( for PCT )the Testosterone Recovery Stack and TCF-1. I have a lot of confidence in this combo right here. If it does not bring me back to 100% fast enough, ill consider more to adding a serm.
    Primordial Performance
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  9. Is a month on a SERM really that toxic? I thought these issues only came up in patients that were on long term SERM use.

  10. or you could just not use steroids, then you'd have nothing to worry about.

    wich is alot better than wondering if that hundred so dollars you spent for pct products is worth it, or even if it'll work.

    trs isn't made for stronger cycles, maybe turinabol, or 1-t, or their new andro series, but something like superdrol, no way.
  11. steakboy
    steakboy's Avatar

    no way dude i'm DONE with PH's. my LDL is messed up hardcore right now. It's only straight up test inj for me in the future.

  12. What will you use for PCT after a test cycle?
  13. steakboy
    steakboy's Avatar

    that's what i was hoping to find out here... maybe raloxifene + TRS.

  14. ralax and torem are supposed to have LOW toxicity levels
    Test e/dbol/epi/winnie
    http://anabolicminds.com/forum/cycle-info/164764-schwellington-has-been.html

  15. Someone should run Clomid and/or Nolva for 4 weeks and get bloods done. I don't think short term use is detrimental..
  16. steakboy
    steakboy's Avatar

    ralox has some pretty big numbers for thrombosis within the first 6 MONTHS of treatment. obviously there's no studies out there that include 4 weeks of treatment...

    anyway, i'm thinking by controlling estrogen DURING and using hcg properlly, then low dosing a SERM and going a little more natural for my PCT i may mitigate SOME of these risks. I'm not a big fan of getting blood work done, but for the sake of science i would love to get some numbers to everybody during 4 weeks of low dosing raloxifene, though i don't think there's any blood work that will show a thrombosis or embolism is on the way. correct me if i'm wrong here...
  17. steakboy
    steakboy's Avatar

    Quote Originally Posted by jbryand101b View Post
    or you could just not use steroids, then you'd have nothing to worry about.

    wich is alot better than wondering if that hundred so dollars you spent for pct products is worth it, or even if it'll work.

    trs isn't made for stronger cycles, maybe turinabol, or 1-t, or their new andro series, but something like superdrol, no way.
    also, not to ignore the validity of this... as i see where you're coming from. steroids is playing with fire. i know this... trust me. I'm not doing this because i think there's no risk of hurting myself, or because i think i'm invincible. what i AM doing is reducing potential risk by re-assessing my options. of course there would be less or no risk of a pulmonary embolism if i didn't do this. sure i would be safer if i didn't.

    Let's take a step back and understand why i'm on here. I want to know a safer (not totally safe and idiot proof) way of getting my goals with what i have available to me.

  18. Quote Originally Posted by jbryand101b View Post
    or you could just not use steroids, then you'd have nothing to worry about.

    wich is alot better than wondering if that hundred so dollars you spent for pct products is worth it, or even if it'll work.

    trs isn't made for stronger cycles, maybe turinabol, or 1-t, or their new andro series, but something like superdrol, no way.
    ^^^This

    Any strong PH/DS or any AAS cycle needs a SERM. Perhaps not at the absurd doses that some AAS users tend to dose tham at, but at reasonable dosing, they are proven to be safe and effective.

    I too find it quite hypocritical of steroid users who introduce an exogenous substance that trashes lipid profiles, stresses the liver, kidneys and prostate, and shuts down endogenous testosterone production, but then blame the SERM to be "bad guy" of the cycle. WTF!?!?

    Generally speaking, SERMs have excellent safety and efficacy records. Of course they have their side effects; but most of the more life threatening sides come at high doses over extended periods of time; certainly not at the doses and time frames that most AAS users use them.

    OP, just as an FYI, Raloxifene is also a SERM and most AI's are pretty damaging to lipid profiles. Something to keep in mind. Nolvadex, Clomid, and Fareston are all very proven, reliable, and safe methods of recovery. I don't buy into the propoganda proposed by many OTC supplement manufacturers. OTC products have their place too, but should be used for very light cycles, as monotherapy, or in conjunction with a SERM during a PCT for stronger PH/DS/AAS cycles.
  19. steakboy
    steakboy's Avatar

    I know ralox is a serm... I think I said that. I know serms aren't the only bad guy here. Wait wait hold on here im trying to get a safer alternative not a flame on what everybody else is saying. I think you're biased on years of broscience and wont take a forward approach on something new. And what do you mean proven? You're saying that everybody on the boards is doing it. Look my first post was about a doctor warning me... so unless you cough up a doctorite im going to believe they aren't as safe as people are lead to believe. Additionally Eric from PP has some pretty convincing evidence.

    Im not entirely sure you read everything here or you're taking things out of context maybe.

    I had to churn this out on my droid so excuse the grammar and spelling.

  20. I'm interested in triptorelin which is an GnRH agonist. Theres only minimal research on it's use, but from what i've seen and heard it looks promising

  21. Quote Originally Posted by Chubbinmuffin View Post
    Someone should run Clomid and/or Nolva for 4 weeks and get bloods done. I don't think short term use is detrimental..
    Blood won't show blood clots. Or other small things that toxicity might do. But if anyone is worried about that, then don't cycle.

    Honestly, if you want to use a SERM, just use toremifene. It's not going to lower IGF-1 or GH. It's purported to have lower toxicity than other SERMs.

    If you want to reduce toxicity even more, run it low dose with the TRS. If you have a vendetta against OTC PCT, don't talk trash on the TRS. Unless you've used it and gotten bloodwork showing it is bad, don't lump it in with other **** like novedex.

    Novedex is why OTC PCT has a bad name. Yes, that stuff IS garbage and enough testimonials from people can pretty much seal that one.
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  22. I've been building my body since 1985 ...

    Did it totally naturally up until this year when I ran an Epistane cycle followed by Torem PCT.

    But ... during all the years I was natural - I had plenty of buddies who did steroids.

    Not an expert - and with the new "designer steroids" that are less suppressive - maybe OTC PCT is the way to go ... I dunno.

    But I can tell you straight up - people went to SERMS because body builders were getting gyno and losing their gains after quitting the juice.

    And the SERMS work. I've never known anyone who had a blood clot, or a stroke, or had their livers explode on a SERM.

    If you go OTC - I won't criticize you. For me actually - I'm scared of Clomid and Nolva, due to other sides I've heard attached to them. Others love Clomid and Nolva. For me - I like Torem (thinking about buying the pills next go-round).

    Different people have different views - that's fine. Some like SERMS, some don't - to each his own.

    Back in 1984, my buddies didn't use anything for PCT. They accepted the fact that they'd lose a percentage of their gains - that kind of sucked.

  23. Quote Originally Posted by BigBlackGuy View Post
    Blood won't show blood clots. Or other small things that toxicity might do. But if anyone is worried about that, then don't cycle.
    I know. I'm curious about liver values since these things are "toxic".

  24. Quote Originally Posted by Chubbinmuffin View Post
    I know. I'm curious about liver values since these things are "toxic".
    Yah, liver toxicity is overstated... but when run after a course of methyls and perhaps in conjunction with drinking (only if someone is really dumb) and aspirin.... then it starts getting wacky.
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  25. steakboy
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    Had bloods done 30 days after mdrol PULSE with otc pct and test levels were fine... more than fine actually. But the LDL levels were waaaay high. All I used for pct was DIM and terrestris. But we all know methyls do this. Sadly my doc didn't mark estradiol in my test so who knows how that was. I had itchy nips the whole way throght the pulse.

    Hey if I get bloods done after my 12 weeks of test and PCT with ralox + trs maybe that will change some minds. I will modify the dosage of ralox if I can get some advice on how I should do it. That's cool if PP wants to shed some light on the subject. Or if anybody else is in the know.

    Thanks for confirming big, no test for thombosis. Guess the only test is having one... and if anybody is confused(thrombosis or deep vein thrombosis(DVT) = blood clot) another possible side effect is pulmonary embolism whish is a clot in the lung)

  26. Quote Originally Posted by HondaV65 View Post
    I've been building my body since 1985 ...

    Did it totally naturally up until this year when I ran an Epistane cycle followed by Torem PCT.

    But ... during all the years I was natural - I had plenty of buddies who did steroids.

    Not an expert - and with the new "designer steroids" that are less suppressive - maybe OTC PCT is the way to go ... I dunno.

    But I can tell you straight up - people went to SERMS because body builders were getting gyno and losing their gains after quitting the juice.

    And the SERMS work. I've never known anyone who had a blood clot, or a stroke, or had their livers explode on a SERM.

    If you go OTC - I won't criticize you. For me actually - I'm scared of Clomid and Nolva, due to other sides I've heard attached to them. Others love Clomid and Nolva. For me - I like Torem (thinking about buying the pills next go-round).

    Different people have different views - that's fine. Some like SERMS, some don't - to each his own.

    Back in 1984, my buddies didn't use anything for PCT. They accepted the fact that they'd lose a percentage of their gains - that kind of sucked.
    Designer steroids aren't less suppressive- tell me Superdrol, or pherplex, or m1t isnt suppressive
    Test e/dbol/epi/winnie
    http://anabolicminds.com/forum/cycle-info/164764-schwellington-has-been.html

  27. Quote Originally Posted by tbonesteakboy View Post
    Had bloods done 30 days after mdrol PULSE with otc pct and test levels were fine... more than fine actually. But the LDL levels were waaaay high. All I used for pct was DIM and terrestris. But we all know methyls do this. Sadly my doc didn't mark estradiol in my test so who knows how that was. I had itchy nips the whole way throght the pulse.

    Hey if I get bloods done after my 12 weeks of test and PCT with ralox + trs maybe that will change some minds. I will modify the dosage of ralox if I can get some advice on how I should do it. That's cool if PP wants to shed some light on the subject. Or if anybody else is in the know.

    Thanks for confirming big, no test for thombosis. Guess the only test is having one... and if anybody is confused(thrombosis or deep vein thrombosis(DVT) = blood clot) another possible side effect is pulmonary embolism whish is a clot in the lung)
    No idea personally on the ralox, officially we tend to find torem the serm of choice. But rather than trying to just give you a google answer, I'll ask around PP for you.
    Just inject.
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  28. Quote Originally Posted by tbonesteakboy View Post
    no way dude i'm DONE with PH's. my LDL is messed up hardcore right now. It's only straight up test inj for me in the future.

    testosterone is a pro hormone btw.
    just saying...

  29. Quote Originally Posted by tbonesteakboy View Post
    I think you're biased on years of broscience and wont take a forward approach on something new.
    Sorry my friend. No "broscience" here, just real science. In fact I hate that term with a passion. It implies group think, and unlike so many other dolts that post on many of the body building forums, I am quite capable of thinking onmy own. Years and years of education allow me to conduct my own research and draw my own conclusions. I won't make mention of my profession, education level, nor do I need to prove anything to you or anyone else. It is not relevant to this discussion.

    Additionally, my PCTs have always been supported by pre, intra, and post cycle blood work, further supporting that SERMs are safe and effective. I can’t say this to be true for many other people on the forum offering up their “awesome knowledge”. I am always responsible with my cycles and can damn well afford a robust cycle, PCT, and the relevant blood work.

    Quote Originally Posted by tbonesteakboy View Post
    And what do you mean proven? You're saying that everybody on the boards is doing it.
    What do I mean by proven? I mean that SERMs have been PROVEN and used for decades now in the medical field, with great success, in both the treatments of cancer as well as fertility issues in both men and women. Nolvadex and Clomid have been around for decades and have been PROVEN safe and effective. Of course you can dissect the side effects and find all sorts of potential scary sides (potential being the key word). But, you can do the same thing with aspirin, ibuprofen, Tylenol, Xanax,, Prozac, Lipitor, and I almost forgot one…steroids…you know, all of those FDA approved pharmaceuticals. I suggest you do a little more research.

    Quote Originally Posted by tbonesteakboy View Post
    Look my first post was about a doctor warning me... so unless you cough up a doctorite im going to believe they aren't as safe as people are lead to believe.
    Umm, so I am suppose to believe third-hand information from you that you obtained from your doctor and that you could have misinterpreted? If you doctor did in fact give you one side of the story, I suggest you find a new doctor. Personally, I think your doctor closer represents a small feathered animal with an elongated beak and webbed feet. Again, there is no need for me to prove any level of education to you or anyone else.

    Quote Originally Posted by tbonesteakboy View Post
    Additionally Eric from PP has some pretty convincing evidence.

    Im not entirely sure you read everything here or you're taking things out of context maybe.
    You do realize that Eric Potratz might, just maybe, have some vested incentive to steer people away from the use of a SERM and into the use of his OTC products? While his articles are interesting and filled with relevant facts and compelling, educated arguments against the use of SERMs, I have read many of them and find them to be somewhat bias toward the use of something he sells rather than being completely objective. While I like and use some PP products, I would never support the use of their products, or any OTC products, alone for PCT. In fact, I believe Eric endorses the use of a moderate SERM in conjunction with his OTC products. This is the same approach I take. Perhaps you should dig up that article.

    My suggestion; do your own research! I have done hundreds of hours of my own reasearch (outside body building and steroid forums) that support that SERMs are safe and highly effective when dosed properly. Then again, each person needs to gain their own personal level of comfort with any substance prior to using it.

    Good luck with finding your safe alternative. Let me know when you come up with the next miracle PCT. Perhaps you can stuff in some LiquaVade. Until then, I will stick to my trusty Clomid. Aahh, Clomid…works EVERY TIME!
  30. steakboy
    steakboy's Avatar

    Lol rage post.

    Anyway let's stay on track. The topic is potential risk with current SERMs and clotting. So far none of us have heard of this happening in the BB community but is there any risk possible? Eric from PP has some interesting information available. If anybody can provide some scientific evidence in the way of medical documentation to back this up...

    Its already well known that most all SERMs cause clotting and other issues but the evidence is presented in longer term patients.

    My original question was how we can mitigate potential risks with some other options. Im willing to try these other options and provide bloodwork for effectiveness, but cannot provide proof that the new method will prevent or reduce risk of clotting. (If method includes any use of a SERM)
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