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Letro

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    Letro


    Anyone with experience reducing Gyno with letro who wouldnt mind sharing their experience I'd appreciate it and would consider them as a friend thanks to all

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    Letro can reduce it, but in my experience, unless it's newly formed (2 years or less, usually, maybe a little longer can get away with it) letro won't cure it. After tapering off letro (hopefully you taper) the gyno will come back when you estrogen reachs homeostasis.
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    Letro works great for ridding gyno.
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    Just make sure you taper if you use it, and maybe another milder AI to come off of it to keep that estro from spiking.
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    Here's a protocol from another forum that I've used with success:

    I am posting this thread to help answer all of the questions regarding gyno prevention and reversal, the use of letrozole and other anti-e’s. I will go over everything in very simple easy to understand language. Also we are talking about estrogen gyno here, not progesterone (but using letro will stop progesterone related problems as well since it inhibits all estrogen anyways). Progesterone gyno will be enlargement of your nipple area, the actual aereola, not a lump under it.

    Let me make this first point very clear, as I state in my signature this is from my personal experience, so whether you agree with it or not is your own issue. I have helped many people with gyno and it has worked just fine for them as well.

    To first understand why you are doing what you are doing I am going to go over a few things and a few definitions:

    SERM – Selective estrogen receptor modulator. These drugs work by binding to the estrogen receptors and flooding them in a sense, making it difficult (but not impossible by any means) for estrogen to bind to the receptors and thus prevent the onset of estrogen related side effects.
    Most common forms: Tamoxifen (Nolvadex), Clomiphene (Clomid)
    AI – Aromatise Inhibitor. These drugs work by inhibiting the aromatization of estrogen. This means that in effect AI’s prevent androgens from converting to estrogen, again, making it difficult (but not impossible) for estrogen to reach receptor sites.
    Most common forms: Anastrozole (l-dex, a-dex), Exemestane (aromasin), Femera (letrozole). For our purpose of reversing gyno we are interested in Letro.

    Letro and your sex drive:
    Letrozole will suppress your sex drive. This is another reason why it is so important to act on preventing gyno as soon as possible. Since we all know that Test should be run in every cycle this will cancel out the effect of sex drive suppression.

    Running letro to prevent gyno:
    If you decide to run estrogen protection while on cycle (and I suggest you do unless you are aware that you do not require it), you can run either a SERM or an AI. Letro will be the most powerful AI you can use, it will inhibit 98+% of estrogen using a dose as low as .25mg and even lower. This is why I suggest you do not use a dose higher than .50mg while on cycle just trying to prevent estrogen related side effects.

    You will want to start running the letro approximately 2 weeks before you begin your cycle to allow it to fully stabilize in your blood. I have often heard the argument that letro takes up to 60 days to stabilize, I don’t know if I buy into this for the reason that I have reversed gyno after using letro for only 1 week. Still to be safe I recommend starting it before your cycle as stated above.

    If you do decide to run letro there is absolutely no need to run another AI or SERM. Do not make the mistake of thinking more is better. Think of it this way; if letro is preventing the conversion of androgens to estrogen than there is no estrogen, what would the purpose of a SERM be when there is no estrogen to bind to the receptors? Nolva will only take away from the effectiveness of letro.

    This brings me to my next point. Do not listen to anyone who tells you to bump up your nolvadex to 60+mg ED if you get gyno. I have no idea where this idea started but I have seen it suggest far too many times recently. Nolvadex will do nothing to reverse your gyno…let me make that clear IT WILL DO NOTHING FOR GYNO. If you are running nolva as your anti-e and start to develop gyno than sure you can bump the dosage a small amount to try to prevent it from progressing further, but letrozole must begin ASAP.

    It is very important that you begin taking letrozole immediately, the longer your wait the more risk you take in not being able to reverse it.

    How do I know if I have gyno?
    If you have developed gyno you will have a lump behind your nipple. It will be fairly hard, and it will be tender to touch.

    Running letro to reverse gyno:
    I am going to go over the three different scenarios which people could fit into. Remember regardless of what scenario you are in it is important that you begin taking the letro ASAP.

    1. Already using an anti-e aside from letro.
    2. Already using letro @ a dose of .25mg or .50mg ED.
    3. Not running any estrogen protection.

    1.
    Day 1: .25mg Letro + anti-e*
    Day 2: .50mg Letro
    Day 3: 1.0mg Letro
    Day 4: 1.5mg Letro
    Day 5: 2.0mg Letro
    Day 6: 2.5mg Letro **

    2.
    Day 1: .50mg Letro
    Day 2: 1.0mg Letro
    Day 3: 1.5mg Letro
    Day 4: 2.0mg Letro
    Day 5: 2.5mg Letro **

    3.
    Day 1: .50mg Letro
    Day 2: 1.0mg Letro
    Day 3: 1.5mg Letro
    Day 4: 2.0mg Letro
    Day 5: 2.5mg Letro **

    *Regardless of the anti-e you are using it is important to still use it for the first day you begin letro as the letro will not have taken any effect and you by no means want your body to be without any protection when gyno is already prevalent.

    ** You will remain at this dose until gyno symptoms subside. Once you believe your gyno is gone it is important to stay at this dose for another 4-7 days to ensure all traces are gone. I recommend people with a bf% over 15 stay on for a week as it may be harder to judge completely whether the lump is completely gone. Once this period is over it will be important to taper letro down slowly rather than coming off it completely. Regardless of which manner you tapered up your dose you will all taper down in the same fashion.

    Day 1: 2.0mg
    Day 2: 1.5mg
    Day 3: 1.0mg
    Day 4: .50mg***
    Day 5: .25mg
    ***You can remain at this dose or go down further to .25mg. It is really up to you at this point. They are both very common maintenance doses as an anti-e while on cycle. Personally I have stayed with .25mg and never had a problem.

    Letro and the estrogen rebound:
    With your estrogen being completely inhibited there is a definite estrogen rebound as your body tries to re-stabilize the testosterone:estrogen balance. We can prevent this rebound effect by supplementing further with another AI or SERM. So, I suggest that when you are coming to the end of your cycle you will more than likely be using Nolva in your PCT so just make sure that you begin taking nolva the last day you are going to take your letro and then continue on as you would with regular PCT.

    This now leads us into the question of reversing gyno while not on cycle. There are a few things to remember here. You have already waited longer than you should have, and your sex drive will be shot. You can use tribulus or another natural test booster to help you in this scenario but I can’t guarantee the effectiveness. Just follow gyno reversal protocols 2 or 3. When coming off again you must taper and begin using nolvadex to prevent any rebound effect that may occur.

    How much nolvadex should you use if you are not going into PCT and running this off cycle? I suggest starting at 20mg ED for a week and then lowering it to 10mg for another week and then coming off completely.
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    Quote Originally Posted by tommygunzz View Post
    Here's a protocol from another forum that I've used with success:

    I am posting this thread to help answer all of the questions regarding gyno prevention and reversal, the use of letrozole and other anti-e’s. I will go over everything in very simple easy to understand language. Also we are talking about estrogen gyno here, not progesterone (but using letro will stop progesterone related problems as well since it inhibits all estrogen anyways). Progesterone gyno will be enlargement of your nipple area, the actual aereola, not a lump under it.

    Let me make this first point very clear, as I state in my signature this is from my personal experience, so whether you agree with it or not is your own issue. I have helped many people with gyno and it has worked just fine for them as well.

    To first understand why you are doing what you are doing I am going to go over a few things and a few definitions:

    SERM – Selective estrogen receptor modulator. These drugs work by binding to the estrogen receptors and flooding them in a sense, making it difficult (but not impossible by any means) for estrogen to bind to the receptors and thus prevent the onset of estrogen related side effects.
    Most common forms: Tamoxifen (Nolvadex), Clomiphene (Clomid)
    AI – Aromatise Inhibitor. These drugs work by inhibiting the aromatization of estrogen. This means that in effect AI’s prevent androgens from converting to estrogen, again, making it difficult (but not impossible) for estrogen to reach receptor sites.
    Most common forms: Anastrozole (l-dex, a-dex), Exemestane (aromasin), Femera (letrozole). For our purpose of reversing gyno we are interested in Letro.

    Letro and your sex drive:
    Letrozole will suppress your sex drive. This is another reason why it is so important to act on preventing gyno as soon as possible. Since we all know that Test should be run in every cycle this will cancel out the effect of sex drive suppression.

    Running letro to prevent gyno:
    If you decide to run estrogen protection while on cycle (and I suggest you do unless you are aware that you do not require it), you can run either a SERM or an AI. Letro will be the most powerful AI you can use, it will inhibit 98+% of estrogen using a dose as low as .25mg and even lower. This is why I suggest you do not use a dose higher than .50mg while on cycle just trying to prevent estrogen related side effects.

    You will want to start running the letro approximately 2 weeks before you begin your cycle to allow it to fully stabilize in your blood. I have often heard the argument that letro takes up to 60 days to stabilize, I don’t know if I buy into this for the reason that I have reversed gyno after using letro for only 1 week. Still to be safe I recommend starting it before your cycle as stated above.

    If you do decide to run letro there is absolutely no need to run another AI or SERM. Do not make the mistake of thinking more is better. Think of it this way; if letro is preventing the conversion of androgens to estrogen than there is no estrogen, what would the purpose of a SERM be when there is no estrogen to bind to the receptors? Nolva will only take away from the effectiveness of letro.

    This brings me to my next point. Do not listen to anyone who tells you to bump up your nolvadex to 60+mg ED if you get gyno. I have no idea where this idea started but I have seen it suggest far too many times recently. Nolvadex will do nothing to reverse your gyno…let me make that clear IT WILL DO NOTHING FOR GYNO. If you are running nolva as your anti-e and start to develop gyno than sure you can bump the dosage a small amount to try to prevent it from progressing further, but letrozole must begin ASAP.

    It is very important that you begin taking letrozole immediately, the longer your wait the more risk you take in not being able to reverse it.

    How do I know if I have gyno?
    If you have developed gyno you will have a lump behind your nipple. It will be fairly hard, and it will be tender to touch.

    Running letro to reverse gyno:
    I am going to go over the three different scenarios which people could fit into. Remember regardless of what scenario you are in it is important that you begin taking the letro ASAP.

    1. Already using an anti-e aside from letro.
    2. Already using letro @ a dose of .25mg or .50mg ED.
    3. Not running any estrogen protection.

    1.
    Day 1: .25mg Letro + anti-e*
    Day 2: .50mg Letro
    Day 3: 1.0mg Letro
    Day 4: 1.5mg Letro
    Day 5: 2.0mg Letro
    Day 6: 2.5mg Letro **

    2.
    Day 1: .50mg Letro
    Day 2: 1.0mg Letro
    Day 3: 1.5mg Letro
    Day 4: 2.0mg Letro
    Day 5: 2.5mg Letro **

    3.
    Day 1: .50mg Letro
    Day 2: 1.0mg Letro
    Day 3: 1.5mg Letro
    Day 4: 2.0mg Letro
    Day 5: 2.5mg Letro **

    *Regardless of the anti-e you are using it is important to still use it for the first day you begin letro as the letro will not have taken any effect and you by no means want your body to be without any protection when gyno is already prevalent.

    ** You will remain at this dose until gyno symptoms subside. Once you believe your gyno is gone it is important to stay at this dose for another 4-7 days to ensure all traces are gone. I recommend people with a bf% over 15 stay on for a week as it may be harder to judge completely whether the lump is completely gone. Once this period is over it will be important to taper letro down slowly rather than coming off it completely. Regardless of which manner you tapered up your dose you will all taper down in the same fashion.

    Day 1: 2.0mg
    Day 2: 1.5mg
    Day 3: 1.0mg
    Day 4: .50mg***
    Day 5: .25mg
    ***You can remain at this dose or go down further to .25mg. It is really up to you at this point. They are both very common maintenance doses as an anti-e while on cycle. Personally I have stayed with .25mg and never had a problem.

    Letro and the estrogen rebound:
    With your estrogen being completely inhibited there is a definite estrogen rebound as your body tries to re-stabilize the testosterone:estrogen balance. We can prevent this rebound effect by supplementing further with another AI or SERM. So, I suggest that when you are coming to the end of your cycle you will more than likely be using Nolva in your PCT so just make sure that you begin taking nolva the last day you are going to take your letro and then continue on as you would with regular PCT.

    This now leads us into the question of reversing gyno while not on cycle. There are a few things to remember here. You have already waited longer than you should have, and your sex drive will be shot. You can use tribulus or another natural test booster to help you in this scenario but I can’t guarantee the effectiveness. Just follow gyno reversal protocols 2 or 3. When coming off again you must taper and begin using nolvadex to prevent any rebound effect that may occur.

    How much nolvadex should you use if you are not going into PCT and running this off cycle? I suggest starting at 20mg ED for a week and then lowering it to 10mg for another week and then coming off completely.
    Alright...when you say cycle?? Do you mean off cycle or gear cycle?
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    question


    Hey buddy - I just read your post regarding letro for gyno removal. Thanks for writing that. I am just coming off cycle from m-stane and also had a pre-existing gyno condition. From previous PH use...I am going to run the letro as u described but i wanted to get the dosing for nolva after i stop the letro and for how long to run it since this is my post cycle...Also - I am going to be taking a natural test booster while on the letro is that ok? And should I take HCG to get my nuts back (they dont seem to have shrunk really)...Does clomid help get the nuts back?...Sorry for all the questions, your help would GREATLY be appreciated and I will of course be helping others with this info thanks!
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    thanks, bookmarked! good info.
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    no two people will have the same experience with dealing with gyno. Letro, clomid/nolva, etc.
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    at what doses did you notice letro hurt muscle gain, strength, libido?
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    Quote Originally Posted by ek00fbp
    Hey buddy - I just read your post regarding letro for gyno removal. Thanks for writing that. I am just coming off cycle from m-stane and also had a pre-existing gyno condition. From previous PH use...I am going to run the letro as u described but i wanted to get the dosing for nolva after i stop the letro and for how long to run it since this is my post cycle...Also - I am going to be taking a natural test booster while on the letro is that ok? And should I take HCG to get my nuts back (they dont seem to have shrunk really)...Does clomid help get the nuts back?...Sorry for all the questions, your help would GREATLY be appreciated and I will of course be helping others with this info thanks!
    Would like to know also, if it's alright to take a test product with letro
    I have gyno on left side it's not bad but it's noticeable and it makes me self conscious about it, last ph run was about a 18months ago and wasn't to bad but I notice it started grow when I stopped working out and started to add weight, will letro still help or is it time for surgery?
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    Also what is the maximum length to run letro?
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    Quote Originally Posted by Bagged01 View Post
    Also what is the maximum length to run letro?
    thats not an easy question to answer. It depends on what your using it for.... it does have side effects of its own so research before you use it
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    Quote Originally Posted by gymrat827

    thats not an easy question to answer. It depends on what your using it for.... it does have side effects of its own so research before you use it
    To help with existing gyno, I have a small lump on the left side only right has nothing, prob been about year 1/2 since last ph use
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    anyone know at what dose does it hinder muscle gain,size,strength at if being ran solo?
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    then you suggest to run nolvadex from the last day of letro's gyno reduction cycle, at 20 mg/day for the first week, then 10 in the second week. But could occur a rebound after nolva?
    Sorry for my bad english in my posts !!
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    Quote Originally Posted by fenix91 View Post
    But could occur a rebound after nolva?
    yes, thats why i have said over and over again to not use nolva to try and get rid of gyno.
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    Quote Originally Posted by bigwhiteguy29 View Post
    anyone know at what dose does it hinder muscle gain,size,strength at if being ran solo?
    .125mg ED or .25mg EOD IMO, it may be different for you.
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    Quote Originally Posted by Bagged01 View Post
    To help with existing gyno, I have a small lump on the left side only right has nothing, prob been about year 1/2 since last ph use
    Use it as long as it takes to get rid of the lump, than taper it down to practically nothing. than switch to adex or aromasin using very low doses.
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    Quote Originally Posted by gymrat827

    Use it as long as it takes to get rid of the lump, than taper it down to practically nothing. than switch to adex or aromasin using very low doses.
    I will try that and see what happens, if not I guess ima be chest heavy to hide it
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