Primordial Performance's Liver Juice-LV. A new on-cycle support supplement. - AnabolicMinds.com

Primordial Performance's Liver Juice-LV. A new on-cycle support supplement.

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    Primordial Performance's Liver Juice-LV. A new on-cycle support supplement.






    This is our new Milk Thistle LV-based product. We have a very nice write-up to go along with this that will be posted up shortly. There is supportive evidence/studies showing Silymarin having the ability to reduce and even prevent instances of pharmacological-induced liver cholestasis (a potential dangerous effect of reduced ductal bile flow within the liver induced by methylated compounds). The night crew gets first crack at this one.

    This is a GREAT addition of prevention for those looking for protection while on-cycle.

    Get it now!

    Click here for Liver Juice-LV!


    Steroids for your Liver

    We think Liver Juice is so awesome; it could be called Liver Steroids.

    But of course, we didn’t want to give the product a bad name.

    It appears that milk thistle does to the liver, what anabolic steroids to do the muscles. Milk thistle turns a weak liver to a strong liver (except milk thistle has zero side effects). (1-4)

    Ironically, after a formal review of the most current scientific literature on milk thistle, it appears milk thistle has specific protective effects against anabolic/androgenic steroid induced liver toxicity. We will present new and exciting research later in this article.

    What’s most disappointing (and damaging to milk thistles reputation) is that 90% of the milk thistle products on the market have super poor absorption at only about 8%. (5-14) Therefore, we had to go the extra mile and create a liquid formula that would actually get milk thistle where it needs to be -- in the liver.

    Before I show you exactly how milk thistle works I want to tell you about our impressive accomplishment with our Liver Juice formula, and the break though delivery system. Read on



    Meeting the challenge – Mr. Milk Thistle


    Try to image mixing a handful of chalk into a glass of water, you would see it either sink to the bottom or precipitate to the top -- that’s pretty close to how well milk thistle mixes into a glass of water.

    To show the exceptional solubility accomplished with the milk thistle in our Liver Juice, we went ahead and took a 5mL dose (500mg) of Liver Juice and mixed it into a glass of water. We then took 500mg of the exact same milk thistle extract used in our Liver Juice, and vigorously shook it into a glass of water. Then they sat for 12 hours



    As you can see, the milk thistle in Liver Juice remained completely stable and molecularly dispersed in the liquid. The milk thistle powder alone simply crashed to the bottom of glass. (“crash” means to crystallize, separate or no longer be in solution -- aka, not be absorbed into the body)

    BTW, what you just witnessed was the result of about 119 hours in the lab, and about 12 months of research.

    Anyway, we managed to make a nice milk thistle formula... but listen to why this is so important...



    Membrane Invagination

    Obviously, milk thistle does not dissolve in water, and hardly dissolves in most oils. (7) This inability to dissolve means milk thistle is very difficult to be absorbed by the human body, since the larger particles cannot pass though the walls of the digestive tract. (5-8, 12) In fact, milk thistle extract alone only absorbs at a rate of about 8% in humans. (5-14)

    Unless nutrients are dispersed to micro-particle size, they simply won't be absorbed by the intestines. In order to get the maximum amount of milk thistle absorbed into the body we had to accomplish 3 things when formulating Liver Juice -

    1. Modify the Liqua-Vade delivery system so milk thistle can complexly dissolve.

    2. Make sure it remains dissolved once mixed in an aqueous environment (such as the stomach).

    3. Make it safe and acceptable for drinking.

    We ended up accomplishing all 3 goals. But it certainly wasn’t easy.



    Editors note: Some of you home chemistry buffs are probably thinking milk thistle could just dissolve into some basic solvent like alcohol or glycerin. That may accomplish the 1st goal, but as soon as those water soluble solvents become diluted in a glass of water they would lose their solvent capacity and that milk thistle would fall out of solution and crash right to the bottom of the glass, therefore putting milk thistle right back to where it started.


    Liqua-Vade – Tailored for Mr. Milk Thistle


    Because the milk thistle flavones are such stubborn little molecules, we had to custom tailor our Liqua-Vade delivery system just for Liver Juice. We used a precise ratio of 12 different pharmaceutical grade carriers, phospholipids and fatty esters to dissolve our high potency milk thistle into a fine homogenous solution (while managing to give it a nice sweet almond taste).

    Rest assured, our Liqua-Vade delivery technology isn’t some hyped up sugar water. It’s based on Self-Emulsifying Drug Delivery System (SEDDS) science, which is backed by dozens of 3rd party human clinical trials and is currently one of the hottest research fields in modern day drug delivery (5-7)

    Over the years there have been other attempts at enhancing delivery of milk thistle, however Liqua-Vade delivery technology (SEDDS) trumps them all. (5-14) Just take a look





    Bile acids - Liver Cleaners

    Bile acids are the liver’s detergents -- flowing through the cellular channels all throughout the liver.

    There are dozens of different bile acids created by the liver, all of which are metabolites of cholesterol. Essentially, they are created to dissolve and mobilize toxic material and export it from the liver and into the intestines for excretion. Different bile acids are needed to dissolve and carry different toxins from the liver.

    In general, bile acids are your friends. However, certain drugs (including methylated steroids) cause the liver to slow bile acid production, and create a bile acid insufficiency, as well as cause a build up in the hepatotoxic bile acids (15-23) This makes a mess, and causes the liver to get jammed up fast. If the liver gets clogged up enough where bile can no longer flow from the biliary channels, a condition develops known as reversible cholestasis. (the primary condition developed from methylated steroids and birth control use) (15-23)

    Luckily this liver condition is reversible. If you have suffered some toxic effects from steroids (or other drugs) you still have a chance to turn it around for the better.


    Bile Acid – The Doctors Choice

    Bile acid is the drug of choice prescribed to anabolic steroids users admitted for drug induced cholestasis. The drug is known as Ursodiol -- a.k.a. ursodeoxycholic acid. This naturally occurring bile acid is known for its hydrophilic action and ability to detoxify the liver by cleaning out less hydrophilic bile acids, among other toxins such as methylated hormone metabolites. (19, 24-27)

    Unfortunately, Ursodiol is an expensive prescription drug, and not easily obtainable.

    As I mentioned earlier, there is new and exciting research on milk thistle that we are excited to present. Research has shown us milk thistle has the ability to increase production of this protective bile acid -- ursodeoxycholic acid (at the same relative dose delivered by Liver Juice) (18-23)


    The West Side Liver Gang – Cleaning up the Trash

    The main active ingredients in milk thistle are flavonolignans, known as silichristin, silidianin, isosilibinin, and the most biologically active player, silybin (Our milk thistle extract is standardized to 30% silybin). (1-4)

    When these milk thistle flavonolignans enter the liver they don’t mess around. They immediately start circulating the liver to signal sluggish and under-producing liver cells to pick up the production of liver cleansing bile acids, esspecialy the hepatoprotective variety such as ursodeoxycholic acid. It appears that silybin stimulates Cyp7a1 and Cyp3a enzymes to encorage conversion of cholesterol towards protective and hydrophilic bile acids. (18-23)

    Now here is the clincher...

    Studies have shown that milk thistle can reverse the down-regulating effect on bile acid production even during the administration of methylated steroids. So when steroids are in the liver inhibiting production of the beneficial bile acids, milk thistle steps in and ramps up beneficial bile acid production while enhancing the export of built up toxins (and methylated steroids) from the liver. (18-23, 28)



    Liver Juice - Quick to Battle

    With our Liqua-Vade delivery system, the active milk thistle flavones will reach the liver fast. Once absorbed through the intestines the biologically active flavones are immediately carried into the liver, where they begin stimulating the liver cells to revive detoxifying bile acid production. (8,9)

    In animals with cholestasis induced from methylated steroids, milk thistle has been shown to significantly restore bile production and bile outflow in less than 5 days. (19-21) However we do encorage "pre-conditioning" the liver with Liver Juice two weeks prior to any methylated oral steroid cycle, while continuing use throughout the entire cycle.



    Liver Juice – The Timeless Miracle Worker

    Liver Juice (milk thistle) has been used safely to treat various liver diseases for thousands of years. Out of the dozens of published scientific papers on milk thistle, no harmful side-effects have ever been found. (1-4)

    It was nearly 2000 years ago when Pliney The Elder noted that milk thistle juice was excellent for “carrying off bile”. (29) I guess it appears he was right after all



    Supplement Facts
    Serving Size: 5cc (5mL oral syringe)

    Servings per container: 50


    Amount Per Serving %DV*


    --------------------------------------------------------------------------------
    Milk Thistle Extract (Silybum marianum) 500mg**

    (standardized to 80% silymarin)


    --------------------------------------------------------------------------------
    Minimum total flavonolignans 400mg**


    --------------------------------------------------------------------------------
    Silybin 150mg**


    --------------------------------------------------------------------------------
    *Daily Value

    **Daily Value not established


    Other Ingredients: Other ingredients: Liqua-Vade Technology [Distilled water, exthoxylated sorbitan trioleate, dimethyl isosorbide, ethyl oleate, sorbitan monolaurate, ethoxylated mono and di-glycerides, medium chain triglycerides, grape spirits, sesame oil, phospholipid complex (phosphatidylcholine, lysophosphatidylcholine), glyceryl triacetate, tocopheryl acetate, hydroxyproply methylcellulose], malt syrup, natural almond flavor, sucralose, trisodium citrate, simethicone, potassium sorbate, sodium benzoate, citric acid†, sucrose†. † Used for food grade adhesive on syringe adapter
    NOTICE:
    No artificial color

    This product is not intended to diagnose, treat, cure, or prevent any disease.



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    Looks like a solid supp.
    Ask me for samples of the new RecoverPRO and Maniac. 3Z is coming July 1st Facebook for more info and maybe a great deal on it coming.
    http://twitter.com/#!/TeamAISports
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    I've added the full write-up to the initial post, everyone.

    - John

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    •   
       

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    Would love to hear feedback from you all.

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    Quote Originally Posted by Trauma1 View Post
    Would love to hear feedback from you all.


    I talked to someone here on the board yesterday who plans to use it soon.
    Ask me for samples of the new RecoverPRO and Maniac. 3Z is coming July 1st Facebook for more info and maybe a great deal on it coming.
    http://twitter.com/#!/TeamAISports
    http://www.facebook.com/AISportsNutrition
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    Quote Originally Posted by pembroke3355 View Post
    I talked to someone here on the board yesterday who plans to use it soon.
    Very nice.

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    think im gonna need a lil of this for up coming cycle

    bold/pmag/alpha 1/6oxo
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    Quote Originally Posted by Trauma1 View Post
    Would love to hear feedback from you all.
    You'll have feedback from me on or around 3/11/10..that's my last dose of liver juice...blookwork before and after...stand tuned
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    I just got my Liver Juice in and took my first dose. I must say that the taste is really good!
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    Quote Originally Posted by Mikey851 View Post
    I just got my Liver Juice in and took my first dose. I must say that the taste is really good!
    Yo bro, you running the liver juice solo or with a cycle?
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    Quote Originally Posted by bulldogz View Post
    Yo bro, you running the liver juice solo or with a cycle?
    I'm running it with a cycle of M14-e.
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    Quote Originally Posted by Mikey851 View Post
    I'm running it with a cycle of M14-e.
    Nice...do you get bloodwork before and after to check up?
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    Quote Originally Posted by bulldogz View Post
    Nice...do you get bloodwork before and after to check up?
    Unfortunately no, I'm in between jobs and don't have full coverage health insurance and can't afford the trip to the doc. I know that's ironic because for the money I paid for my cycle and supporting supps plus pct I could go to the doc lol; but then I wouldn't be running a cycle.

    All I know is that the last time I got bloodwork when I had insurance, my values were in range.
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    Liver Juice is legit, alot better than pill form. Im not going to run anything without this!!
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    Quote Originally Posted by trojanman1016 View Post
    Liver Juice is legit, alot better than pill form. Im not going to run anything without this!!
    Yo bro...if you have a lil extra cash check out private md labs...its a great investment for people running cycle to see their values and/or how long it takes to get back to baseline, especially when running harsh compounds...just my .02

    Sorry, quoted the wrong person...meant for Mikey...
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    Quote Originally Posted by bulldogz View Post
    Yo bro...if you have a lil extra cash check out private md labs...its a great investment for people running cycle to see their values and/or how long it takes to get back to baseline, especially when running harsh compounds...just my .02

    Sorry, quoted the wrong person...meant for Mikey...
    Alright man, i'll check it out. That would be nice to at least see my values after pct.
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    Id like to see a bigger bottle of Liver Juice. Other than that, im just goin to order more bottles per order.
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    Jake (Antaeus Labs Owner) mentioned Liver Juice in his blog post about Ultradrol liver protection; he says 2-3 dosings a day should be good to go for Ultradrol!
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    Quote Originally Posted by BigBlackGuy View Post
    Jake (Antaeus Labs Owner) mentioned Liver Juice in his blog post about Ultradrol liver protection; he says 2-3 dosings a day should be good to go for Ultradrol!
    Also to negate the taste (although after a few doses it is almost a sweet taste, and not too bad) just throw it in a shake. You really don't notice it at all.
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    Quote Originally Posted by BigBlackGuy View Post
    Jake (Antaeus Labs Owner) mentioned Liver Juice in his blog post about Ultradrol liver protection; he says 2-3 dosings a day should be good to go for Ultradrol!
    I use it, it's the best milk thistle product available

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    Quote Originally Posted by BigBlackGuy View Post
    Jake (Antaeus Labs Owner) mentioned Liver Juice in his blog post about Ultradrol liver protection; he says 2-3 dosings a day should be good to go for Ultradrol!
    Ultradrol and its blood work is looking good lately. Liver Juice and Ultradrol pairing makes huge sense though.
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    Quote Originally Posted by rulk22 View Post
    Ultradrol and its blood work is looking good lately. Liver Juice and Ultradrol pairing makes huge sense though.
    I would add TUDCA to that mix

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    Quote Originally Posted by ryansm View Post
    I would add TUDCA to that mix
    Along with NAC (which gets overlooked far too much).
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    Quote Originally Posted by Rodja

    Along with NAC (which gets overlooked far too much).
    I agree but does anyone know of any supplements that actually have a decent bioavailabilty of NAC. This seems to always be a major downside to it.
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    Quote Originally Posted by cbruno924 View Post
    I agree but does anyone know of any supplements that actually have a decent bioavailabilty of NAC. This seems to always be a major downside to it.
    Unless treating an acute situation (e.g. acetaminophen overdose), oral will suffice for protection.
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    Quote Originally Posted by Rodja

    Unless treating an acute situation (e.g. acetaminophen overdose), oral will suffice for protection.
    Thank you Rodja, good to know!
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    Quote Originally Posted by Rodja View Post
    Along with NAC (which gets overlooked far too much).
    NAC is a staple and should be for everyone else when using harsh methyls

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    Quote Originally Posted by ryansm View Post
    NAC is a staple and should be for everyone else when using harsh methyls
    I would even say that a half dose should be used for daily protection.
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    Quote Originally Posted by Trauma1 View Post




    This is our new Milk Thistle LV-based product. We have a very nice write-up to go along with this that will be posted up shortly. There is supportive evidence/studies showing Silymarin having the ability to reduce and even prevent instances of pharmacological-induced liver cholestasis (a potential dangerous effect of reduced ductal bile flow within the liver induced by methylated compounds). The night crew gets first crack at this one.

    This is a GREAT addition of prevention for those looking for protection while on-cycle.

    Get it now!

    Click here for Liver Juice-LV!


    Steroids for your Liver

    We think Liver Juice is so awesome; it could be called Liver Steroids.

    But of course, we didn’t want to give the product a bad name.

    It appears that milk thistle does to the liver, what anabolic steroids to do the muscles. Milk thistle turns a weak liver to a strong liver (except milk thistle has zero side effects). (1-4)

    Ironically, after a formal review of the most current scientific literature on milk thistle, it appears milk thistle has specific protective effects against anabolic/androgenic steroid induced liver toxicity. We will present new and exciting research later in this article.

    What’s most disappointing (and damaging to milk thistles reputation) is that 90% of the milk thistle products on the market have super poor absorption at only about 8%. (5-14) Therefore, we had to go the extra mile and create a liquid formula that would actually get milk thistle where it needs to be -- in the liver.

    Before I show you exactly how milk thistle works I want to tell you about our impressive accomplishment with our Liver Juice formula, and the break though delivery system. Read on



    Meeting the challenge – Mr. Milk Thistle


    Try to image mixing a handful of chalk into a glass of water, you would see it either sink to the bottom or precipitate to the top -- that’s pretty close to how well milk thistle mixes into a glass of water.

    To show the exceptional solubility accomplished with the milk thistle in our Liver Juice, we went ahead and took a 5mL dose (500mg) of Liver Juice and mixed it into a glass of water. We then took 500mg of the exact same milk thistle extract used in our Liver Juice, and vigorously shook it into a glass of water. Then they sat for 12 hours



    As you can see, the milk thistle in Liver Juice remained completely stable and molecularly dispersed in the liquid. The milk thistle powder alone simply crashed to the bottom of glass. (“crash” means to crystallize, separate or no longer be in solution -- aka, not be absorbed into the body)

    BTW, what you just witnessed was the result of about 119 hours in the lab, and about 12 months of research.

    Anyway, we managed to make a nice milk thistle formula... but listen to why this is so important...



    Membrane Invagination

    Obviously, milk thistle does not dissolve in water, and hardly dissolves in most oils. (7) This inability to dissolve means milk thistle is very difficult to be absorbed by the human body, since the larger particles cannot pass though the walls of the digestive tract. (5-8, 12) In fact, milk thistle extract alone only absorbs at a rate of about 8% in humans. (5-14)

    Unless nutrients are dispersed to micro-particle size, they simply won't be absorbed by the intestines. In order to get the maximum amount of milk thistle absorbed into the body we had to accomplish 3 things when formulating Liver Juice -

    1. Modify the Liqua-Vade delivery system so milk thistle can complexly dissolve.

    2. Make sure it remains dissolved once mixed in an aqueous environment (such as the stomach).

    3. Make it safe and acceptable for drinking.

    We ended up accomplishing all 3 goals. But it certainly wasn’t easy.



    Editors note: Some of you home chemistry buffs are probably thinking milk thistle could just dissolve into some basic solvent like alcohol or glycerin. That may accomplish the 1st goal, but as soon as those water soluble solvents become diluted in a glass of water they would lose their solvent capacity and that milk thistle would fall out of solution and crash right to the bottom of the glass, therefore putting milk thistle right back to where it started.


    Liqua-Vade – Tailored for Mr. Milk Thistle


    Because the milk thistle flavones are such stubborn little molecules, we had to custom tailor our Liqua-Vade delivery system just for Liver Juice. We used a precise ratio of 12 different pharmaceutical grade carriers, phospholipids and fatty esters to dissolve our high potency milk thistle into a fine homogenous solution (while managing to give it a nice sweet almond taste).

    Rest assured, our Liqua-Vade delivery technology isn’t some hyped up sugar water. It’s based on Self-Emulsifying Drug Delivery System (SEDDS) science, which is backed by dozens of 3rd party human clinical trials and is currently one of the hottest research fields in modern day drug delivery (5-7)

    Over the years there have been other attempts at enhancing delivery of milk thistle, however Liqua-Vade delivery technology (SEDDS) trumps them all. (5-14) Just take a look





    Bile acids - Liver Cleaners

    Bile acids are the liver’s detergents -- flowing through the cellular channels all throughout the liver.

    There are dozens of different bile acids created by the liver, all of which are metabolites of cholesterol. Essentially, they are created to dissolve and mobilize toxic material and export it from the liver and into the intestines for excretion. Different bile acids are needed to dissolve and carry different toxins from the liver.

    In general, bile acids are your friends. However, certain drugs (including methylated steroids) cause the liver to slow bile acid production, and create a bile acid insufficiency, as well as cause a build up in the hepatotoxic bile acids (15-23) This makes a mess, and causes the liver to get jammed up fast. If the liver gets clogged up enough where bile can no longer flow from the biliary channels, a condition develops known as reversible cholestasis. (the primary condition developed from methylated steroids and birth control use) (15-23)

    Luckily this liver condition is reversible. If you have suffered some toxic effects from steroids (or other drugs) you still have a chance to turn it around for the better.


    Bile Acid – The Doctors Choice

    Bile acid is the drug of choice prescribed to anabolic steroids users admitted for drug induced cholestasis. The drug is known as Ursodiol -- a.k.a. ursodeoxycholic acid. This naturally occurring bile acid is known for its hydrophilic action and ability to detoxify the liver by cleaning out less hydrophilic bile acids, among other toxins such as methylated hormone metabolites. (19, 24-27)

    Unfortunately, Ursodiol is an expensive prescription drug, and not easily obtainable.

    As I mentioned earlier, there is new and exciting research on milk thistle that we are excited to present. Research has shown us milk thistle has the ability to increase production of this protective bile acid -- ursodeoxycholic acid (at the same relative dose delivered by Liver Juice) (18-23)


    The West Side Liver Gang – Cleaning up the Trash

    The main active ingredients in milk thistle are flavonolignans, known as silichristin, silidianin, isosilibinin, and the most biologically active player, silybin (Our milk thistle extract is standardized to 30% silybin). (1-4)

    When these milk thistle flavonolignans enter the liver they don’t mess around. They immediately start circulating the liver to signal sluggish and under-producing liver cells to pick up the production of liver cleansing bile acids, esspecialy the hepatoprotective variety such as ursodeoxycholic acid. It appears that silybin stimulates Cyp7a1 and Cyp3a enzymes to encorage conversion of cholesterol towards protective and hydrophilic bile acids. (18-23)

    Now here is the clincher...

    Studies have shown that milk thistle can reverse the down-regulating effect on bile acid production even during the administration of methylated steroids. So when steroids are in the liver inhibiting production of the beneficial bile acids, milk thistle steps in and ramps up beneficial bile acid production while enhancing the export of built up toxins (and methylated steroids) from the liver. (18-23, 28)



    Liver Juice - Quick to Battle

    With our Liqua-Vade delivery system, the active milk thistle flavones will reach the liver fast. Once absorbed through the intestines the biologically active flavones are immediately carried into the liver, where they begin stimulating the liver cells to revive detoxifying bile acid production. (8,9)

    In animals with cholestasis induced from methylated steroids, milk thistle has been shown to significantly restore bile production and bile outflow in less than 5 days. (19-21) However we do encorage "pre-conditioning" the liver with Liver Juice two weeks prior to any methylated oral steroid cycle, while continuing use throughout the entire cycle.



    Liver Juice – The Timeless Miracle Worker

    Liver Juice (milk thistle) has been used safely to treat various liver diseases for thousands of years. Out of the dozens of published scientific papers on milk thistle, no harmful side-effects have ever been found. (1-4)

    It was nearly 2000 years ago when Pliney The Elder noted that milk thistle juice was excellent for “carrying off bile”. (29) I guess it appears he was right after all



    Supplement Facts
    Serving Size: 5cc (5mL oral syringe)

    Servings per container: 50


    Amount Per Serving %DV*


    --------------------------------------------------------------------------------
    Milk Thistle Extract (Silybum marianum) 500mg**

    (standardized to 80% silymarin)


    --------------------------------------------------------------------------------
    Minimum total flavonolignans 400mg**


    --------------------------------------------------------------------------------
    Silybin 150mg**


    --------------------------------------------------------------------------------
    *Daily Value

    **Daily Value not established


    Other Ingredients: Other ingredients: Liqua-Vade Technology [Distilled water, exthoxylated sorbitan trioleate, dimethyl isosorbide, ethyl oleate, sorbitan monolaurate, ethoxylated mono and di-glycerides, medium chain triglycerides, grape spirits, sesame oil, phospholipid complex (phosphatidylcholine, lysophosphatidylcholine), glyceryl triacetate, tocopheryl acetate, hydroxyproply methylcellulose], malt syrup, natural almond flavor, sucralose, trisodium citrate, simethicone, potassium sorbate, sodium benzoate, citric acid†, sucrose†. † Used for food grade adhesive on syringe adapter
    NOTICE:
    No artificial color

    This product is not intended to diagnose, treat, cure, or prevent any disease.


    One of the best liver care products and it's only 20 bucks

  

  
 

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