But how does AB really work?
- 06-21-2011, 08:14 AM
But how does AB really work?
Im really stoked about Anabeta being released since I so far has loved all your products. But even though the info is here I find it a bit unclear how it works. Since its anabolic and not in a steroidal way, is it a SARM? Is it possible to get more specific detailes on the way of action?
- 06-21-2011, 11:37 AM
Its effects would be considered non-AR mediated anabolic. Even in anabolics that have been researched for years and in humans that have significant non-AR mediated effects the exact non-AR effects are yet to be determined. But Bill Roberts suspects "Unfortunately we cannot yet identify how many non-AR-mediated activities there may be. There are I think at least two: activity in microsomes and activities in nerves. There may be more. For example, differentiation of satellite cells of muscle into mature muscle cells might be a non-AR mediated activity."
This is a quote in reference to non-AR mediated steroids, not AnaBeta.
- 06-21-2011, 11:43 AM
I could imagine AnaBeta to be VERY synergetic with Ecdysterone ... would you agree ?
06-21-2011, 02:16 PM
Ecdy has never really produced real world results IMO...could be synergistic but also I would not want to risk any competition in the body between the two.
I would just use AnaBeta by itself. Some BCAAs or LCLT if you want to stack it with something
06-21-2011, 02:18 PM
06-22-2011, 12:45 PM
06-22-2011, 12:52 PM
06-22-2011, 01:22 PM
I had the same thoughts about Ecdy, first that it would be synergistic, and second that I've never experienced any good results from it!
I think the recommendation for BCAA and LCLT are spot on though, there's plenty of evidence there.
06-22-2011, 01:26 PM
06-25-2011, 08:26 PM
Here is a great tid-bit Kevinhy dug up:
The biological activity of testosterone and dihydrotestosterone is thought to occur predominantly through binding to the androgen receptor (AR), a
member of the nuclear receptor superfamily that functions as a ligand-activated transcription factor. However, androgens have also been reported
to induce the rapid activation of kinase-signaling cascades and modulate intracellular calcium levels. These effects are considered to be nongenomic because they occur in cell types that lack a functional AR, in the presence of inhibitors of transcription and translation, or are observed to
occur too rapidly to involve changes in gene transcription. Such nongenomic effects of androgens may occur through AR functioning in the cytoplasm to induce the MAPK signal cascade. In addition, androgens may function through the sex hormone binding globulin receptor and possibly a
distinct G protein-coupled receptor to activate second messenger signaling mechanisms. The physiological effect of nongenomic androgen action has yet to be determined. However, it may ultimately contribute to regulation of transcription factor activity, including mediation of the transcriptional activity of AR. (Molecular Endocrinology 16: 2181–2187, 2002).
I dont expect anyone to fully understand that, but rather just trust what we are trying to explain
06-25-2011, 09:41 PM
06-25-2011, 10:02 PM
PES - PM me anytime for any questions
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06-25-2011, 10:44 PM
06-25-2011, 11:11 PM
06-25-2011, 11:54 PM
06-26-2011, 07:24 AM
06-26-2011, 07:27 AM
Now the $1M question is which secondary pathway is being used (IGF-1, GH, MGF, myostatin, others)? That's a tough one, and ultimately not that important IMO (some better than others) as long as the results work out with no real negative sides.
06-26-2011, 10:39 AM
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