Alpha T2 and Serotonin
- 09-06-2010, 07:18 AM
Alpha T2 and Serotonin
Let me preface this by saying that I am loving Alpha T2 and think it is probably the best fat loss product I have ever taken.
I have taken an extremely low dose of Sertraline(zoloft) off and on since 2005 - due to bad anxiety that started happening to me as a result of PTSD from an accident. When I started taking Alpha T2 I was only taking 12.5mg of sertraline a day.
I ran it by my doctor who was unfortunately clueless about the ingredients in Alpha T2(aside from the T2) and couldn't provide me any direction - I stopped taking my sertraline because of the warning on the Alpha T2 bottle about mixing it with SSRI's.
What I'm curious about is could somebody shed light on what issue could arise from mixing the 2 and what the result could be? My guess is that it would be something along the lines of Serotonin Syndrome. My hope is to take some info from here back to my doctor to get final direction from him about what to do.
The reason I ask is because even on THAT low of a dose I am still getting wicked bad withdrawal symptoms so I am trying to appease those as best as possible. Ultimately I am hopeful that I can take 12.5mg a day along with the Alpha T2 without compromising my health.
Thanks for any input!
- 09-06-2010, 06:17 PM
It is common for many supplements to not be added to prescription drugs, especially SSRI's.
As for Alpha-T2, the only known effect on serotonin (not necessarily the only though) is the Rauwolscine HCL ingredient. Rauwolscine is a 5-HT1A receptor agonist.
Agonism of this receptor can decrease depression, decrease anxiety, help lower blood pressure and heart rate, etc according to what I have read.
Alpha-T2 should not be used with an SSRI because you do not want to have competition with your prescription on those receptors. Alpha-T2 also is not marketed to treat any type of disorders associated with anxiety or depression just because it has an agonistic effect on 5-HT1A.
But as for info to take back with you to the doctor, tell your doctor there is an ingredient that contains a 5-HT1A receptor agonist and he/she will understand what that means (hopefully).
- 09-07-2010, 05:42 PM
Thanks, I appreciate your input! What you said makes sense, I am hopeful my doctor can advise accordingly.
09-07-2010, 10:23 PM
Great post man! Sorry for your PTSD man. Thank you for keeping us safe.
If I'm not mistaken, doesn't nolvadex compete with ssri,s? And if so I'm sure many people have taken nolva while one anti depressants.
Why is it so bad for the two to compete? I know you're not my doctor natty but if you have an idea I'd like to hear it.
Oh and I'm on paxil cuz I use to be OCD.
09-07-2010, 11:59 PM
09-08-2010, 10:22 AM
Hahaha. Lmao! Oh shet I completely misread that one. I guess I read PTSD and just thought military. Haha. Oh well. I'm sure PTSD of any kind blows. I know anxiety from OCD feels horrible. My chest would feel like complete trash by the end of the day. I'm just saying so what if alpha and my paxil compete for that receptor. How can it hurt me other than not treating my anxiety? And if that's it then I think I can make it for one month on a mean a$$ cutting stack
09-08-2010, 11:50 AM
09-09-2010, 01:38 PM
09-09-2010, 08:25 PM
Yeah I can vouche for that. But still... What harm will come from taking alpha t2 while on a ssri? Will it just prevent the ssri from releiving anxiety?
09-09-2010, 08:39 PM
But you certainly do not want to take a supplement that would compete with an SSRI...which in theory it could (depending on the SSRI). That is why we advise to not take it with SSRIs
09-09-2010, 09:25 PM
Thanks natty. I know as a rep you couldn't say a whole lot. But I appreciate you taking the time to answer. Maybe I'll just be a crazy b!tch and try it anyways. I already ordered alpha oep and erase. It's to good of a stack to not try it. So I'll see what happens. Your advice was recieved for the record. Haha
10-15-2010, 08:17 AM
hi im a new member and v. interested in taking alpha t2 although im on ant-depressants it seems the most primary concern is SSRI's and im not taking that particular brand, does anyone know if the risks are primarily concerned with SSRI's? Also if anyone has went ahead and taken the supplement regardless could you let me know what happened?
10-15-2010, 03:40 PM
There are multiple types of serotonin receptors, each with different functions. The chemical mentioned above is an agonist at one of them and an antagonist at two of them.
Most antidepressants involve serotonin reuptake inhibition, either selectively or in combination with other neurotransmitters. Wellbutrin is one of the few that does not involve serotonin.
The problem with dealing with this kind of brain chemistry is that it is so complex and there are so many variables that there is no way to predict how a person will react to a drug before they try it. Often finding the right drug to treat depression is a trial and error process.
So what does this mean for you? That there is no way to tell ahead of time how the chemical in AT2 will affect you. We could have 10 guys in here on the same drug as you for the same symptoms, and we could see 10 different reactions.
I am not a doctor and the above is not medical advice.
10-15-2010, 09:08 PM
10-16-2010, 06:22 PM
Yeah consulting with your doctor would be the best. I didn't consult with mine and just went ahead and started out on alpha, oep, and erase. Personally it had no noticeable effects on me. I'm on 40 mg of paxil daily and have had no problems other than being sensitive to the stims. So I just dose my stack according to feel. It's a great stack and I'm cutting fat nicely.
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