Recently I have been taking 50mg of benadryl before bed to prevent the down-regulation of the beta-2 receptor from ephedrine and I have noticed that my muscular recovery seems to have improved. I am wondering about how benadryl could improve recovery. I would guess that it may be due to a reduction or inhibition of histamine-induced cortisol secretion (histamine has been shown to enhance secretion of ACTH and cortisol);
Histamine-induced cortisol secretion from bovine a...[Jpn J Pharmacol. 1997] - PubMed Result
(WO/2007/076140) TREATMENT METHODS EMPLOYING HISTAMINE H3 RECEPTOR ANTAGONISTS, INCLUDING BETAHISTINE
Has anyone else experienced this?
Histamine-induced cortisol secretion from bovine a...[Jpn J Pharmacol. 1997] - PubMed Result
(WO/2007/076140) TREATMENT METHODS EMPLOYING HISTAMINE H3 RECEPTOR ANTAGONISTS, INCLUDING BETAHISTINE
Has anyone else experienced this?