Has anyone ever ingested sodium bicarbonate with their Adderall? I know it's dangerous, and basically crack. I also know if can potentiate the effects.
never heard of this before...anyone know what negative effects it could have?
Sodium Bicarbonate upps the absorption (or the absorption rate?) of adderall. Obviously I'm no expert, but it has something to do with your stomach/intestines being effected by an alkalizer or an alkaline substance. Alkalizers potentiate the effects of adderrall, that much I know.
To your question, let's say that sodium bicarbonate DOES potentiate the effects of adderall. In that case, you would get stronger positive effects from the adderall as well as stronger negative effects, such as shaking or rapid heartbeat.
Be careful, good luck. Post if you decide to do it (not recommending it), I'm just curious now.
If you wanted to hasten the results of adderall couldn't you just crush it up and put it under your tongue?
In the case of Adderall what they are attempting to do is to alkalize the urine. Due to the chemistry of the molecule this creates more of an unionized shift since you are placing a basic amine group on the amphetamine molecule in a basic environment. When you have unionized drug in the renal tubular filtrate you increase tubular reabsorption which decreases how much of the drug is excreted. This is a common method by a lot of druggies actually when taking things like crystal meth.
In other instances urinary alkalinization can actually help in overdose situations, but not this one.
I have seen studies where there is a 30% absolute difference in drug concentrations of high urinary pH vs. normal urinary pH.
Doctor of Pharmacy
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