5HTP and Melatonin

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  1. I only take Melatonin when Im working Midnight shifts and during the winter months. Seems to keep me in a better mood during those brutally boring months of January, Feb and March.


  2. u wont have to take much melatonin cause the 5htp increases melatonin and hcg levels by itself
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  3. Just ask the pharmacist when your there. That is what they are there for. I can tell you they will say it is ok and if you take too much you will just pee it out

  4. I take substantial doses of melatonin at night and have for years. Not addicted to it, nor do I have any sides from it. On the contrary, I feel pretty good on it. Pretty sure my pineal gland is fine and dandy. IMO, the melatonin that doesn't bind to the appropriate receptors is used as an antioxidant.

    5-htp I only take when I feel depression coming on...usually in the dead of winter. I have found that taking it first thing in the morning on an empty stomach get the most bang for the buck seratonin-wise. 50-100mg is more than enough for me, particularly used in combination with 50mg P-5-P. This combo definitely has a kick to it...in a good way.

    I would be way more cautious of overdosing 5-HTP than melatonin.

  5. i used melatonin to enhance sleep, 1mg, headache in the morning and still get up at the same time.
    i don't have problem fall asleep, but i have problem for waking too early.

    but if i use it for jetlag, no headache, good sleep, good drug for that.
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  6. I never had an issue. taken 500mg of 5htp and 3mg of Melatonin. I've still been taking Melatonin, but I no longer taking 5htp do to taking St. Johns Wart.

  7. Correct me if I'm wrong, but wouldn't chronic supplementation of 5-HTP be suppressive to endogenous production?

    Or does it not operate on that kind of feedback loop?
  8. purebred
    purebred's Avatar

    Quote Originally Posted by WannaBeHulk View Post
    i agree, 3 mg is a bit much. it has too long of a half life so i wake up feeling groggy everytime i take melatonin. i like theanine a couple hours before bed and tryptophan .5-1 hour before. works great in my experiences!
    how long of a half-life does melatonin have?

  9. how long of a half-life does melatonin have?
    30-50% Bioavailability and a 35-50 minute half life. My guess this is in part due to being a potent antioxidant.
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