5HTP and Melatonin

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  1. I never had an issue. taken 500mg of 5htp and 3mg of Melatonin. I've still been taking Melatonin, but I no longer taking 5htp do to taking St. Johns Wart.

  2. Correct me if I'm wrong, but wouldn't chronic supplementation of 5-HTP be suppressive to endogenous production?

    Or does it not operate on that kind of feedback loop?
  3. purebred
    purebred's Avatar

    Quote Originally Posted by WannaBeHulk View Post
    i agree, 3 mg is a bit much. it has too long of a half life so i wake up feeling groggy everytime i take melatonin. i like theanine a couple hours before bed and tryptophan .5-1 hour before. works great in my experiences!
    how long of a half-life does melatonin have?

  4. how long of a half-life does melatonin have?
    30-50% Bioavailability and a 35-50 minute half life. My guess this is in part due to being a potent antioxidant.


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