Cialis vs Viagra

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  1. I prefer Levitra at 2.5-5mg. Viagra gives me all kinds of sides.


  2. Cialis works for me even if I drank. But I won't have started drinking right when I took it. IT would have been earlier in the day.

    Cialis also seems to take a few hours for it to be at peak effectiveness.
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  3. Quote Originally Posted by anab0lix View Post
    Cialis works for me even if I drank. But I won't have started drinking right when I took it. IT would have been earlier in the day.

    Cialis also seems to take a few hours for it to be at peak effectiveness.
    Word, that's true. Tadalafil improves testosterone levels as well, by reducing E2 levels.

    J Sex Med. 2006 Jul;3(4):716-22.
    Testosterone:estradiol ratio changes associated with long-term tadalafil administration: a pilot study.
    Greco EA1, Pili M, Bruzziches R, Corona G, Spera G, Aversa A.
    Author information
    Abstract
    INTRODUCTION:
    It has been reported that lack of sexual activity due to erectile dysfunction (ED) may be associated with testosterone (T) decline.
    AIM:
    To investigate whether the known changes in sex hormones associated with resumption of sexual activity are sustained in the long term.
    MAIN OUTCOME MEASURES:
    Primary endpoints were variations from baseline of steroid hormones: total T, free T (f T), and estradiol (E). Secondary endpoints were variations of erectile function domain scores at International Index of Erectile Function-5 (IIEF-5).
    METHODS:
    In an open-label fashion, 20 patients (mean age 54.8 +/- 8.4 years) received tadalafil 10-20 mg on demand for 12 months. Exclusion criteria were those reported for phosphodiesterase inhibitors, including hypogonadism and hyperprolactinemia.
    RESULTS:
    Tadalafil assumption was safe and well tolerated (overall adverse effects in 15% of patients) and none discontinued medication. A significant decrease in E levels occurred at the end of the study (from 19.9 +/- 9.6 to 16.6 +/- 8.1 ng/dL, P = 0.042 vs. baseline), with parallel increase in the T:E ratio (26.3 +/- 15.3 to 32.6 +/- 17.7, P = 0.05), whereas no changes in T and f T serum levels were observed, respectively (411.4 +/- 131.4 to 434.2 +/- 177.1 ng/dL and 47.7 +/- 15.3 to 49.9 +/- 19.1 pmol/L, not significant). Interestingly, nonparametric subgroup analysis for related samples revealed that E decrease was detectable only in lean (N = 14) but not in obese (N = 6, body mass index > 27.5 kg/m2) subjects (17.8 +/- 10.1 vs. 13.5 +/- 6.8, P < 0.05). A net increase in IIEF-5 scores was observed at the endpoint (13.7 +/- 5.9 vs. 25.7 +/- 2.9, P < 0.0001).
    CONCLUSIONS:
    Sustained improvement in sexual function after 12 months of tadalafil administration is associated with increased T:E ratio mainly related to reduction of E levels. We hypothesize that androgen-estrogen cross-talk and possible inhibition of aromatase activity during chronic exposure to tadalafil might have a role in the regulation of erectile function.
    PMID: 16839328 [PubMed - indexed for MEDLINE]
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