I'll be honest with you all, I've tried every drug mentioned in this thread (and then some) SSRI's balance you. When your down, they lift you. But if you up, they bring you down. They are only good for situational, emotional depression. Not to mention the ejaculatory failure than can make you even more deppressed than you were to begin with! Celexa was suppose to be "the one", but it has the same sides as the rest. Plus, the day you stop taking SSRI's the benefit ends. You crash and burn (no residual benefits at all) Prozac is the only one that doesn't put me on the toilet. The rest play hell on my gut.
I didn't get relief until I started taking Synthroid and Dexadrine. Amphetamines are superior for deppression IMO over serotonergic drugs. Norepinephrine is the neurochemical that activates you when depressed. Dopamine enhances intrest and exploratory activity. Serotonin is a mellowing substance. Even drugs like Effector and Serzone, which have mixed activity, were to melloving for me. There are some new SNEI's out there now I think that would work great. I have also tried every tricyclic too, they're not a good solution either. Wellbuterin is an amphetamine derivative, but it's cardiotoxic and depersonalizing, at least for me. There are much cleaner sympathomimetics out there. Ask your doc for Dexedrine, Adderal, Adipex, Prelu-2, Tenuate or Pemoline. The effectiveness of each of these is that order. This class of drug also has good residual. The longer you take it, the more likely the benefit is to stick and be permenant when you stop. Otherwise, pray and never give up, no matter what.