Raloxifen

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  1. Quote Originally Posted by turkish
    Checked the prices, letro is also too expensive. Back to ATD.

    Wouldn't raloxifene be good in preventing gyno while on cycle, since it seems to be effective for reducing it?
    Yeah, that's a good choice too @ 60mg/d, pretty cheap


  2. Quote Originally Posted by DR.D
    Yeah, that's a good choice too @ 60mg/d, pretty cheap
    Thanks again doc. This means I'll go with Raloxifene on cycle and save the ATD for PCT alongside Nolva & Fenugreek.
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  3. can you combine letro with rebound fighting gyno

  4. Dr.D I have a question and maybe you can help answer it. From what I've read letro takes about 60 days to acheive steady blood plasma levels so what im wondering is it pointless to take letro for short periods of time i.e. 2-3 weeks?

  5. Quote Originally Posted by stumbras
    can you combine letro with rebound fighting gyno
    Yes!
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  6. Quote Originally Posted by dadream
    Dr.D I have a question and maybe you can help answer it. From what I've read letro takes about 60 days to acheive steady blood plasma levels so what im wondering is it pointless to take letro for short periods of time i.e. 2-3 weeks?
    This is true, but short term letro is still OK because steady state levels are not really needed with letro. The optimal dose is 0.25mg/d, so your levels are pretty much high enough right from the start, especially if you pre-load with a full dose (2.5mg/d) for the first week before switching to a low, maintenance dose of 0.1-0.25mg/d.

  7. Quote Originally Posted by DR.D
    Yes!
    is it worth it, rebound is weaker so how its gona be beneficier to letro
    add that dose of rebound should i use
    i am on my test cycle now and using letro 1.25 md ed trying to reverse small case of gyno
    but it is still here should i add other compounds(reboun 3 tabs) or use letro 2.5 mg ed
    Last edited by stumbras; 04-18-2006 at 12:09 AM.

  8. Quote Originally Posted by stumbras
    is it worth it, rebound is weaker so how its gona be beneficier to letro
    add that dose of rebound should i use
    i am on my test cycle now and using letro 1.25 md ed trying to reverse small case of gyno
    but it is still here should i add other compounds(reboun 3 tabs) or use letro 2.5 mg ed
    That's probably too much letro, unless your doing 2g or more of test per week. If you do high doses of letro, it can rebound and it's really so strong, you don't need that much anyway. You could combine letro and RXT to conserve on the RXT, like 25mg RXT w/ 0.1mg letro instead of 50mg of RXT by itself. I like letro at 0.25mg/d max. EOD at that dose has always been plenty with 600-800g of test e/wk.

  9. Quote Originally Posted by DR.D
    That's probably too much letro, unless your doing 2g or more of test per week. If you do high doses of letro, it can rebound and it's really so strong, you don't need that much anyway. You could combine letro and RXT to conserve on the RXT, like 25mg RXT w/ 0.1mg letro instead of 50mg of RXT by itself. I like letro at 0.25mg/d max. EOD at that dose has always been plenty with 600-800g of test e/wk.
    Hey bro, was watching the Nightly News at work the other night and guess what "new" drug is being marketed for breast cancer?

    Thought about the good old Doc whenever it came on.

  10. Quote Originally Posted by Grassroots082
    Hey bro, was watching the Nightly News at work the other night and guess what "new" drug is being marketed for breast cancer?

    Thought about the good old Doc whenever it came on.
    Yep saw that too, it's Evista (brand name for Ralox) I liked it at 80 mg during my last cycle for gyno prevention

  11. Yeah, we certainly seem to be on the cutting edge. It would make things so much easier if it worked the other way around!

  12. Quote Originally Posted by Iron Warrior
    Yep saw that too, it's Evista (brand name for Ralox) I liked it at 80 mg during my last cycle for gyno prevention
    How were your gains IW? Toxicity is low to none with Raloxifene correct Doc? Same with Tormifene correct? Damn Nolva and Clomid I still like Clomid, but after my last bloodwork I think I will pass.

  13. Quote Originally Posted by Grassroots082
    Toxicity is low to none with Raloxifene correct Doc? Same with Tormifene correct? Damn Nolva and Clomid I still like Clomid, but after my last bloodwork I think I will pass.
    Yes, raloxifene toxicity is very low. Toremifene is low relative to the others in it's class. What did the Clomid do to your bloodwork? It doesn't allow liver enzymes a chance to drop very fast after a heavy cycle, but that's the only bad thing I ever noticed with it from PCT bloodwork.

  14. It wasn't anything that bad, but it definately did not help.

    Plus the studies about tamoxifen causing carcinogen tumors in rats livers are enough for me not to use it anymore especially now that these two SERM's are readily available (Raloxifene and Tormifene). But I definately felt like my body reacted better to the Clomid than the Nolva.

  15. Quote Originally Posted by DR.D
    Letro 0.1-0.25mg/d, Rebound 25-50mg/d, or Nolva 10-20mg/d in that order of preference
    if aromasin doesnt cause rebound they why dont you like that? because price? and im curious as to where adex would rank with you...do you not like it because it is the same as letro just not as strong? Im trying to come up with the best gyno protection on cycle, i was going to use adex and proviron (not at the same time) but where would you place proviron beginning of or ending of cycle? sorry for all the q's, hope you answer...

  16. Quote Originally Posted by pistonpump
    if aromasin doesnt cause rebound they why dont you like that? because price? and im curious as to where adex would rank with you...do you not like it because it is the same as letro just not as strong? Im trying to come up with the best gyno protection on cycle, i was going to use adex and proviron (not at the same time) but where would you place proviron beginning of or ending of cycle? sorry for all the q's, hope you answer...
    Yeah, Aromasin a good compound for sure and has once a day convenience of dosing. It's just over priced for what it does and what else is out there. I like Adex, but mg/mg letro is the easy winner. There are other differences too, but letro is just more efficient if not any more effective than dex. Proviron is hit or miss for me. It seems to work much better and cover more bases at the end of a cycle, but once again for the price it's benefits are not always consistent it seems. I guess if you took high doses it may work better, but I'm not that rich or well connected!

  17. here is a link to a thread i just posted. its from another board stating why aromasin is the best choice anti-e. Dr D, what are your opinions on this?

    http://anabolicminds.com/forum/stero...tml#post605197

  18. Quote Originally Posted by pistonpump
    here is a link to a thread i just posted. its from another board stating why aromasin is the best choice anti-e. Dr D, what are your opinions on this?

    http://anabolicminds.com/forum/stero...tml#post605197
    The problem is that estrogen formation is still inhibited with Aromasin, just the same as letro and anastrazole. Only SERMs block receptors and leave estrogen in your system but it doesn't matter anyway because that estrogen can't bind to express itself. Only more estrogenic SERMs improve cholesterol. Nolva only does in a relative way but still makes you a stroke candidate as one of it's major sides. Clomid is much better. Anyway, I still like RXT and Reload best. RXT may not be as potent as Aromasin but it doesn't form an androgenic metabolite like Aromasin so it's still better suited for PCT. It actually acts as a mild anti-androgen centrally so it elevates LH by that mechanism as well to compensate for its lower potency. Reload is better yet because lipids improve as estrogen falls and test elevation is the best of any of the 3 of them. It is also more potent than Aromasin. That's just my observation. Aromasin was really tailored to fight breast cancer, but it's still a good compound. I just do not see it as the best, at least not for PCT. Also, anastrazole will cause rebound just the same as letro. They are both enzyme inhibitors that act on the same system using the same mechanism.
  19. Question


    Quote Originally Posted by DR.D
    The problem is that estrogen formation is still inhibited with Aromasin, just the same as letro and anastrazole. Only SERMs block receptors and leave estrogen in your system but it doesn't matter anyway because that estrogen can't bind to express itself. Only more estrogenic SERMs improve cholesterol. Nolva only does in a relative way but still makes you a stroke candidate as one of it's major sides. Clomid is much better. Anyway, I still like RXT and Reload best. RXT may not be as potent as Aromasin but it doesn't form an androgenic metabolite like Aromasin so it's still better suited for post cycle therapy. It actually acts as a mild anti-androgen centrally so it elevates LH by that mechanism as well to compensate for its lower potency. Reload is better yet because lipids improve as estrogen falls and test elevation is the best of any of the 3 of them. It is also more potent than Aromasin. That's just my observation. Aromasin was really tailored to fight breast cancer, but it's still a good compound. I just do not see it as the best, at least not for post cycle therapy. Also, anastrazole will cause rebound just the same as letro. They are both enzyme inhibitors that act on the same system using the same mechanism.

    I have run ralox my last PCT, it worked perfectly,the best sofar! I have used much Nolva in the past. I usually run it for two weeks @40 mg/ed. Could you please elaborate on the "stroke canidate" aspect of the Nolva, is that from clotting or blood pressure? thanks

  20. Quote Originally Posted by DR.D
    Anyway, I still like RXT and Reload best. RXT may not be as potent as Aromasin but it doesn't form an androgenic metabolite like Aromasin so it's still better suited for post cycle therapy. It actually acts as a mild anti-androgen centrally so it elevates LH by that mechanism as well to compensate for its lower potency. Reload is better yet because lipids improve as estrogen falls and test elevation is the best of any of the 3 of them.
    Should read that Reload can be used instead of a SERM for the PCT of a light cycle?

    And how does compare "stroke candidate" potential of toremifene compared to tamoxifene? Sorry guys if this question is out of topic.

  21. Quote Originally Posted by DR.D
    The problem is that estrogen formation is still inhibited with Aromasin, just the same as letro and anastrazole. Only SERMs block receptors and leave estrogen in your system but it doesn't matter anyway because that estrogen can't bind to express itself. Only more estrogenic SERMs improve cholesterol. Nolva only does in a relative way but still makes you a stroke candidate as one of it's major sides. Clomid is much better. Anyway, I still like RXT and Reload best. RXT may not be as potent as Aromasin but it doesn't form an androgenic metabolite like Aromasin so it's still better suited for post cycle therapy. It actually acts as a mild anti-androgen centrally so it elevates LH by that mechanism as well to compensate for its lower potency. Reload is better yet because lipids improve as estrogen falls and test elevation is the best of any of the 3 of them. It is also more potent than Aromasin. That's just my observation. Aromasin was really tailored to fight breast cancer, but it's still a good compound. I just do not see it as the best, at least not for PCT. Also, anastrazole will cause rebound just the same as letro. They are both enzyme inhibitors that act on the same system using the same mechanism.
    sorry DR. i was actually refering to on cycle as far as using aromasin and nolva. I was totally thinkin about something else but it looks like aromasin and nolva on cycle is good prevention against gyno but I will compare prices of aromasin and RXT and if the overall cycle price is lower i would probably go with RXT...wait, this anti-e thing is just confusing the f*cl< out of me, period! guess i just have to try them all out.

  22. Quote Originally Posted by anabolicrhino
    I have run ralox my last post cycle therapy, it worked perfectly,the best sofar! I have used much Nolva in the past. I usually run it for two weeks @40 mg/ed. Could you please elaborate on the "stroke canidate" aspect of the Nolva, is that from clotting or blood pressure? thanks
    Yeah, I'm with ya on the ralox, good stuff. It's just not cost effective for me but 240mg/d is very nice and very non-toxic too. Perfect half-life also. It's just very poorly bioavailable and expensive. An injectable would be sweet and take very low doses (like 5-10mg).

    Yeah, clotting is one of the main complications with Nolva use. Venous thromboembolic disorders (like DVT). Nolva is classified as a known human carcinogen as well. Hmmm, maybe that why doctors only use it on people who are dieing anyway! Wake up people!! End the Nolva madness. OK, ok, I'll leave Nolva alone. I've used it a time or two myself, I'd just avoid it if you could.

  23. Quote Originally Posted by Rostam
    Should read that Reload can be used instead of a SERM for the post cycle therapy of a light cycle?

    And how does compare "stroke candidate" potential of toremifene compared to tamoxifene? Sorry guys if this question is out of topic.
    I think so, yes. On a light oral only cycle of 3-4wks, a steroidal AI is just fine IMO. That's just from my experience. Everybody is different and you won't really know for yourself until you try it and see.

    Toremifene does appear to carry a similar thromboembolic risk as Nolva in the North American studies, but at about 3x the dose. Plus, there not a big warning in the PDR on it's monograph page like there is for Nolva, so I trust it a bit more at this point. I take it for granted that my cholesterol stays low and my blood stays thin because I take T4 year round, but for the general pop, half an aspirin a day would not be a bad idea during PCT with any SERM.

  24. Quote Originally Posted by pistonpump
    sorry DR. i was actually refering to on cycle as far as using aromasin and nolva. I was totally thinkin about something else but it looks like aromasin and nolva on cycle is good prevention against gyno but I will compare prices of aromasin and RXT and if the overall cycle price is lower i would probably go with RXT...wait, this anti-e thing is just confusing the f*cl< out of me, period! guess i just have to try them all out.
    I really like RXT on cycle. That's my choice, or low dose letro. If a SERM is needed on cycle, ralox for sure.

  25. I had a couple of questions about Ralox.

    1.) Rebound: Should I end my gyno-reduction cycle with 60mg of Ralox or 30mg, in order to avoid rebound? (I plan on doing 120mg for the first week, followed by a cruise dose of 60mg for about 2 months.

    2.) Would taking RXT during my Ralox dosing do anything? If Ralox is taking care of the estrogen receptors, what purpose would RXT serve?

    *Looking in Dr. D's direction!*
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