I think the merits of ALCAR and r-ALA (Na-ALA, etc.) are well established. Many recommend the antioxidant benefits of ALA as a safeguard when cranking up mitochondrial activity with high doses of ALCAR. The issue is that ALA has a short half-life of like 25-30min. To really have a window of synergy you would need a sustained release form on ALA.
Why the hell isnt there a bulk SR Na-ALA (or r-ala) + ALCAR capped combo capsule out there? This seems like it would be hot. It would be at the top of my list of supplements. Is there not enough demand? I think LEF makes a really overpriced SR r-ala and I have seen some ALA/ALCAR combo caps from various companies. Still, I have yet to see a well priced combo like the one I speak of. What a shame... Until then I guess its just bulk na-ala and alcar.