[Goose]

I see that one of the benefits of Poseidon is increased red blood cell count. I've read/heard that men shouldn't really be increasing their red blood cell count all that much. How much is increased and is there a need for concern?

Thanks.

[prld2gr8ns]

Originally Posted by Goose

I see that one of the benefits of Poseidon is increased red blood cell count. I've read/heard that men shouldn't really be increasing their red blood cell count all that much. How much is increased and is there a need for concern?

Thanks.

It's nothing that will EVER be considered dangerous. The precise formula of Poseidon offers you just enough B-12/folic ratios to help you notice an overall "boost" in your step by your body's naturally ability to synethesis RBC's by demethylating folic acid and enabling it to be incorporated into hemaglobin synthesis. The methionine synthase enzyme responsible for folic conversion is rate limiting, thus allowing appropriate production levels.

[B5150]

Originally Posted by prld2gr8ns

It's nothing that will EVER be considered dangerous.

Out of curiosity are there studies to even support the claim? How much is "nothing that will EVER be considered dangerous"?

I would suspect that people with already elevated hematocrit, hemaglobin and other RBC byproducts should consider the implication for use of such a product.

There are plenty of references on the net with a google.

Here's a thread on the board: Donating blood and hematocrit

[prld2gr8ns]

Originally Posted by B5150

Out of curiosity are there studies to even support the claim? How much is "nothing that will EVER be considered dangerous"?

I would suspect that people with already elevated hematocrit, hemaglobin and other RBC byproducts should consider the implication for use of such a product.

There are plenty of references on the net with a google.

Here's a thread on the board: Donating blood and hematocrit

B, the question was in regards to increasing RBC count in a general individual(which I took as a healthy individual). If a person is suffering from hemachromotosis, defects in IRP(iron response proteins) translation, and/or their binding elememts, or any other genetic defect that would cause an elevated RBC count then yes individuals should be wary of consuming excessive amounts of hemaglobin synthesizing compounds as well as those involved in the cell cycle mitosis cascade.

In a completely healthy individual, however, there would be no need for concern. No toxic or adverse effects have been associated with large intakes of vitamin B12/folic acid from food or supplements in healthy people.... iron on the other hand is a different story.

[B5150]

Originally Posted by prld2gr8ns

B, the question was in regards to increasing RBC count in a general individual(which I took as a healthy individual). If a person is suffering from hemachromotosis, defects in IRP(iron response proteins) translation, and/or their binding elememts, or any other genetic defect that would cause an elevated RBC count then yes individuals should be wary of consuming excessive amounts of hemaglobin synthesizing compounds as well as those involved in the cell cycle mitosis cascade.

In a completely healthy individual, however, there would be no need for concern. No toxic or adverse effects have been associated with large intakes of vitamin B12/folic acid from food or supplements in healthy people.... iron on the other hand is a different story.

Of course in a healthy individual this is nothing to be concerned about.

As a person who is only a carrier for hemachromotisic (I posses one of the DNA mutations) and who tends to also have higher iron, RBC and hematocrit values it struck my curiosity as I am always very cautious in these matters.

Many people have hemachromotosis and/or are carriers and are unaware until complications of iron overload take place which is usually later in life after their 40's or more. It was only by accident that I even found out myself, as I had no complications or issues, but am now more conscious of this.

Certainly this is not cause for concern, as you said, with an otherwise normal individual.

[Goose]

Thanks for the response and info! Much appreciated.

[prld2gr8ns]

Originally Posted by B5150

Of course in a healthy individual this is nothing to be concerned about.

As a person who is only a carrier for hemachromotisic (I posses one of the DNA mutations) and who tends to also have higher iron, RBC and hematocrit values it struck my curiosity as I am always very cautious in these matters.

Many people have hemachromotosis and/or are carriers and are unaware until complications of iron overload take place which is usually later in life after their 40's or more. It was only by accident that I even found out myself, as I had no complications or issues, but am now more conscious of this.

Certainly this is not cause for concern, as you said, with an otherwise normal individual.

Glad you caught it my friend. Which mutation do you have, IRP or IRE?

Weird that I have never found any studies positively correlating Hemachromotosis with excessive B12/folic intake. Perhaps it's something science may be looking into, as the porphryin ring stucture is dependent upon these two vitamins while the bulk of the O2 binding capacity and subsequent cell functionality is carried out by Fe. The regulating cpd seems to be Fe, as the apoenzyme by itself cannot carry out O2 binding, only when it's bound to free heme can it functionally become an RBC. Interesting...

[B5150]

Originally Posted by prld2gr8ns

Glad you caught it my friend. Which mutation do you have, IRP or IRE?

Weird that I have never found any studies positively correlating Hemachromotosis with excessive B12/folic intake. Perhaps it's something science may be looking into, as the porphryin ring stucture is dependent upon these two vitamins while the bulk of the O2 binding capacity and subsequent cell functionality is carried out by Fe. The regulating cpd seems to be Fe, as the apoenzyme by itself cannot carry out O2 binding, only when it's bound to free heme can it functionally become an RBC. Interesting...

I tested positive for H63D and negative for C282Y.

What trigger the testing was my high iron count. I also drew attention to a trend of blood work that showed and increase in RBC and hematocrit.

I am only a carrier of one gene and I do not have hemachromotosis but I do have issues with high iron levels and therefore frequent a blood bank as often as I can.