Pill promises to stop Alzheimer's
07-23-2006 02:02 PM
Pill promises to stop Alzheimer's
New hope for Alzheimer's cure
July 23, 2006 12:00am
Pill promises to stop Alzheimer's - BN Victoria - Breaking News 24/7 - NEWS.com.au
IN a world first, Melbourne scientists have developed a once-a-day pill that they claim may cure Alzheimer's disease. Human trials of the drug start next month.
The drug -- called PBT2 -- was developed by a team from the Mental Health Research Institute of Victoria in collaboration with Melbourne-based Prana Biotechnology.
"It is a major breakthrough and very much a Melbourne discovery," said Prof George Fink, the director of the Mental Health Research Institute.
"Though much depends on the next phase of human clinical trials . . . early results indicate this drug offers hope to people with Alzheimer's disease," he said.
The revolutionary drug stops the buildup of a protein called amyloid.
Many scientists accept amyloid is a major cause of Alzheimer's as the protein is thought to cause the brain to "rust".
Prof Fink said the drug could significantly prevent Alzheimer's developing or delay the on-set of the brain disease for many years.
Early clinical testing has confirmed the drug is fast-acting. Levels of amyloid dropped by 60 per cent within 24 hours of a single dose.
It found also that PBT2 suppresses the impairment of memory function.
More human studies begin in Sweden next month and Australians will join a major international trial of the drug next year.
Alzheimer's is a progressive and fatal brain disease. It is the major form of dementia, a disease that affects one in four Australians over the age of 60.
Prof Fink said the institute was optimistic about the results of clinical trials and said the drug could be on the market within four years.
Netlink: Alzheimers Australia
07-23-2006 03:04 PM
Wow, this is huge. Hopefully this stuff will work out
07-23-2006 03:15 PM
Yeahright. Did you notice any additional info reguarding dimentia? Was it said to have any memory redeeming qualities?
Originally Posted by yeahright
Preventing Alzheimer's development or delaying the onset is great news. However I'm curious but doubtfull to see if it can actually reverse existing deteriorative conditions such as hallucinations caused by dimentia.
07-23-2006 03:56 PM
Great post....hope the good news stays good news and we don't get failures in human trials.
07-23-2006 10:53 PM
I was skeptical about this where I first saw it posted so I tracked it back to the original Aussie newspaper which appears to be a legitimate news outlet. After checking this, I decided it was legit enough to post here but all I know is what is in this article. It sounds too good to be true but there ya have it. Came out in Australia this weekend.....will be interesting to see if it gets picked up around the world in the new week.
07-24-2006 03:26 AM
07-24-2006 05:56 PM
No kidding. This would be an amazing breakthrough even if it's just 10% as effective as initial testing indicates.
Originally Posted by bioman
07-25-2006 12:56 AM
07-25-2006 12:59 AM
That would be nice if it works out, my friends dad has Alzheimer's and I get bummed out when I see the poor man
07-25-2006 01:47 AM
07-25-2006 10:13 AM
I don't think that this "pill" will work to "cure" someone who already has Alzheimer's, but may slow its progression.
But I think that this "study" assumes too much, that is, that amylase is the primary catalyst for the development of Alzheimer's and I'm not sure that modern science has yet come up with a single cause. I believe it is a result of many factors working together.
Every single human, if they live long enough, will develop Alzheimer's. That is what I have read in research.
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