Stem Cells Advance

  1. Elite Member
    yeahright's Avatar
    Join Date
    Jul 2005
    Posts
    6,368
    Rep Power
    10347
    Level
    52
    Lv. Percent
    98.41%
    Achievements Activity ProPosting ProPosting Authority

    Post Stem Cells Advance


    Stem Cells Advance

    The Herald

    06-16-06

    SCOTTISH scientists have discovered a gene which could be the key to the ability to harvest embryonic stem cells from adult body cells.

    The gene, named Nanog, after the mythical Celtic land of the ever young, was discovered by Professor Austin Smith and his team at Edinburgh University and reported in the journal, Nature. They showed Nanog helps reprogram adult mouse cells into "pluripotent" embryonic stem cells.

    Stem cells are master cells in the body. Scientists believe they could act as a type of human repair system to provide new therapies for illnesses ranging from diabetes to Parkinson's.

    Stem cells found in early embryos have the potential to make any type of cell or tissue. Adult stem cells have a more limited range.

    Converting adult stem cells into an embryonic state would eliminate the use of early embryos, which is a scientific and ethical stumbling block for researchers.

  2. New Member
    Dave@NU's Avatar
    Join Date
    Aug 2005
    Posts
    21
    Rep Power
    124
    Level
    4
    Lv. Percent
    22.62%

    That's awesome yet I fear some how the religious right will still object to it. Is there any information on how it works or is it just a possibilty that it could allow for differentiation in adult stem cells?
  3. Elite Member
    yeahright's Avatar
    Join Date
    Jul 2005
    Posts
    6,368
    Rep Power
    10347
    Level
    52
    Lv. Percent
    98.41%
    Achievements Activity ProPosting ProPosting Authority

    Gene may mean adult cells can be reprogrammed

    By Reuters
    Clearance Center - Overstock Electronics, Discount Computers, Refurbished Electronics, business2-cnet.com.com/Gene+may+mean+adult+cells+can+ be+reprogrammed/2100-1008_3-6083878.html

    Story last modified Wed Jun 14 14:59:58 PDT 2006

    advertisement

    A gene named after the mythical Celtic land of the ever young could help explain how to reprogram adult cells into embryonic stem cells to treat diseases, researchers said on Wednesday.

    They discovered that the gene called Nanog helped to transform adult mouse cells into embryonic stem cells after cell fusion--when two cells are combined to form a hybrid.

    "The effect of Nanog is remarkable. All the hybrid cells became fully converted to embryonic stem cells," said Jose Silva of the University of Edinburgh, Scotland, who reported the findings in the journal Nature.

    Stem cells are master cells in the body. Scientists believe they could act as a type of human repair system to provide new therapies for illnesses ranging from diabetes to Parkinson's.

    Embryonic stem cells found in early embryos have the potential to make any type of cell or tissue. Adult stem cells have a more limited range.

    Converting adult stem cells into an embryonic state would eliminate the use of early embryos, which is a scientific and ethical stumbling block for researchers.

    Professor Austin Smith, who headed the team, said Nanog is not the only gene involved in reprogramming. There could be several that are important for the process.

    He believes the discovery of Nanog, which was named after the mythological Celtic land Tir nan Og, will speed up the search for the others.

    "We anticipate now that people will find the other genes, possibly quite quickly," he said in an interview.

    Peter Mountford, of the biotechnology company Stem Cell Science, which licenses the technology used in the research, said the study shows Nanog can play a dominant role in stem cell research.

    "It represents a major step forward toward reprogramming adult cells without the need to make human embryos," he said in a statement.

    The scientists fused mouse embryonic stem cells with adult brain cells. Adding Nanog increased the number of hybrid cells, which all behaved like embryonic stem cells. The hybrid cells also displayed the capability to form into different cell types.

    Smith hopes that in the future scientists will be able to expose adult stem cells to Nanog and the other genes to reprogram them to an embryonic state without using cell fusion or nuclear transfer, the technique used to create Dolly the cloned sheep.

    "What's important about the research is that it gives us the first glimpse that this may be possible and that it will be a phenomenon that we will be able to understand and explain in latter attempts," he added.
    •   
       

Similar Forum Threads

  1. Scientists create artificial liver from stem cells
    By yeahright in forum News and Articles
    Replies: 3
    Last Post: 11-15-2006, 03:12 AM
  2. Replies: 0
    Last Post: 09-07-2006, 01:13 AM
  3. Gene Found to Switch Off Stem Cells During Aging
    By yeahright in forum News and Articles
    Replies: 0
    Last Post: 09-06-2006, 11:08 PM
  4. Muscle Stem Cells Transformed Into Cartilage
    By LakeMountD in forum News and Articles
    Replies: 0
    Last Post: 01-31-2006, 12:34 AM
  5. Stem cells
    By Jeff in forum Politics
    Replies: 33
    Last Post: 10-15-2004, 05:37 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in