Japanese radish sprout showed hypoglycemic activity and improved lipid metabolism in rats

NewsRx.com

06-15-06

Japanese radish sprout showed hypoglycemic activity in both normal and diabetic rats and improved lipid metabolism in normal rats.

According to recent research published in the journal Phytotherapy Research, "No information is available about the effects of Japanese radish sprout (JRS) on diabetes. To clarify the effects, the influence of JRS on carbohydrate and lipid metabolisms was investigated in normal and streptozotocin-induced diabetic rats. The rats were fed a diet containing 0, 2.5 or 5% of JRS ad libitum for 21 days."

H. Taniguchi and colleagues at the Tokyo University of Agriculture found, Compared with the corresponding control groups, the JRS-fed normal rats showed lower plasma levels of total cholesterol (TC), triglycerides (TG), phospholipids (PL), fructosamine, glucose and insulin and higher plasma levels of low-density lipoprotein-cholesterol, whereas the JRS-fed diabetic rats showed lower plasma levels of fructosamine, glucose and insulin without changes in the plasma lipid parameters. JRS also decreased the hepatic TC, TG and PL levels in the normal rats and the TG level in the diabetic rats."

"These results showed," concluded the authors, "that JRS [showed] hypoglycemic activity in both the normal and diabetic rats and partly improved lipid metabolism in the normal rats. JRS has the potential to alleviate hyperglycemia in cases where diabetes is present and to serve in the primary prevention of diabetes mellitus."

Taniguchi and colleagues published their study in Phytotherapy Research (Effect of Japanese radish (Raphanus sativus) sprout (Kaiware-daikon) on carbohydrate and lipid metabolisms in normal and streptozotocin-induced diabetic rats. Phytother Res, 2006;20(4):274-278).

For additional information, contact H. Taniguchi, Tokyo University of Agriculture, Dept. Nutrit Science, Faculty Applied Bioscience, Setagaya Ku, 1-1-1 Sakuragaoka, Tokyo 1568502, Japan.

The publisher's contact information for the journal Phytotherapy Research is: John Wiley & Sons Ltd., the Atrium, Southern Gate, Chichester PO19 8SQ, W Sussex, England.

Keywords: Tokyo, Japan, Alternative Medicine, Biotechnology, Carbohydrate Metabolism, Diabetes, Diabetes Mellitus, Endocrinology, Hyperglycemia, Hypoglycemic Effect, Insulin, Lipid Metabolism, Lipoprotein, Phytotherapy Research, Streptozotocin, Japanese Radish Sprout, Raphanus sativus, Kaiware-daikon. This article was prepared by Biotech Week editors from staff and other reports.