yeahright
Well-known member
- Awards
- 1
Antiobesity effect of epigallocatechin gallate from green tea deserves more attention
NewsRx.com
04-14-06
The antiobesity effect of epigallocatechin gallate from green tea deserves more attention.
"During the last decade, the traditional notion that green tea consumption benefits health has received significant scientific attention and, particularly, the areas of cardiovascular disease and cancer were subject to numerous studies. Due to the ever-growing obesity pandemic, the antiobesity effects of green tea are being increasingly investigated in cell, animal, and human studies," scientists in Switzerland report in their review.
S. Wolfram and colleagues working with DSM Nutrition Products summarized, "Green tea, green tea catechins, and epigallocatechin gallate (EGCG) have been demonstrated in cell culture and animal models of obesity to reduce adipocyte differentiation and proliferation, lipogenesis, fat mass, body weight, fat absorption, plasma levels of triglycerides, free fatty acids, cholesterol, glucose, insulin and leptin, as well as to increase beta-oxidation and thermogenesis.
"Adipose tissue, liver, intestine, and skeletal muscle are target organs of green tea, mediating its antiobesity effects. Studies conducted with human subjects report reduced body weight and body fat, as well as increased fat oxidation and thermogenesis and thereby confirm findings in cell culture systems and animal models of obesity. There is still a need for well-designed and controlled clinical studies to validate the existing and encouraging human studies.
The authors concluded, "Since EGCG is regarded as the most active component of green tea, its specific effects on obesity should also be investigated in human trials."
Wolfram and colleagues published their review in Molecular Nutrition & Food Research (Antiobesity effects of green tea: From bedside to bench. Mol Nutr Food Res, 2006;50(2):176-187).
For additional information, contact S. Wolfram, DSM Nutrition Products, Dept. Human Nutrition & Health, POB 3255, Bldg 205-020, CH-4002 Basel, Switzerland.
The publisher's contact information for the journal Molecular Nutrition & Food Research is: Wiley-V C H Verlag GmbH, PO Box 10 11 61, D-69451 Weinheim, Germany.
Keywords: Basel, Switzerland, Adipose Tissue, Angiology, Cardiology, Cardiovascular, Cardiovascular Disease, Clinical Studies, Epidemiology, Epigallocatechin Gallate, Green Tea, Human, Lipogenesis, Obesity, Vascular Disease. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2006, Biotech Business Week via NewsRx.com.
To see more of the NewsRx.com, or to subscribe, go to http://www.newsrx.com.
NewsRx.com
04-14-06
The antiobesity effect of epigallocatechin gallate from green tea deserves more attention.
"During the last decade, the traditional notion that green tea consumption benefits health has received significant scientific attention and, particularly, the areas of cardiovascular disease and cancer were subject to numerous studies. Due to the ever-growing obesity pandemic, the antiobesity effects of green tea are being increasingly investigated in cell, animal, and human studies," scientists in Switzerland report in their review.
S. Wolfram and colleagues working with DSM Nutrition Products summarized, "Green tea, green tea catechins, and epigallocatechin gallate (EGCG) have been demonstrated in cell culture and animal models of obesity to reduce adipocyte differentiation and proliferation, lipogenesis, fat mass, body weight, fat absorption, plasma levels of triglycerides, free fatty acids, cholesterol, glucose, insulin and leptin, as well as to increase beta-oxidation and thermogenesis.
"Adipose tissue, liver, intestine, and skeletal muscle are target organs of green tea, mediating its antiobesity effects. Studies conducted with human subjects report reduced body weight and body fat, as well as increased fat oxidation and thermogenesis and thereby confirm findings in cell culture systems and animal models of obesity. There is still a need for well-designed and controlled clinical studies to validate the existing and encouraging human studies.
The authors concluded, "Since EGCG is regarded as the most active component of green tea, its specific effects on obesity should also be investigated in human trials."
Wolfram and colleagues published their review in Molecular Nutrition & Food Research (Antiobesity effects of green tea: From bedside to bench. Mol Nutr Food Res, 2006;50(2):176-187).
For additional information, contact S. Wolfram, DSM Nutrition Products, Dept. Human Nutrition & Health, POB 3255, Bldg 205-020, CH-4002 Basel, Switzerland.
The publisher's contact information for the journal Molecular Nutrition & Food Research is: Wiley-V C H Verlag GmbH, PO Box 10 11 61, D-69451 Weinheim, Germany.
Keywords: Basel, Switzerland, Adipose Tissue, Angiology, Cardiology, Cardiovascular, Cardiovascular Disease, Clinical Studies, Epidemiology, Epigallocatechin Gallate, Green Tea, Human, Lipogenesis, Obesity, Vascular Disease. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2006, Biotech Business Week via NewsRx.com.
To see more of the NewsRx.com, or to subscribe, go to http://www.newsrx.com.
