Mighty mice hold key to muscle-wasting disease

  1. New Member
    picasso's Avatar
    Join Date
    Jun 2005
    Age
    52
    Posts
    78
    Rep Power
    155
    Level
    8
    Lv. Percent
    38.19%

    Mighty mice hold key to muscle-wasting disease


    Mighty mice hold key to muscle-wasting disease
    • A drug that builds up muscle in mice could be used to treat people suffering from diseases such as muscular dystrophy
    THANKS to research on "mighty mice", the lives of people suffering from muscle-wasting diseases such as muscular dystrophy could be transformed. Two treatments that block a protein called myostatin, which slows muscle growth, are now in the pipeline.
    The first approach, announced this week, aims to use a drug to mop up myostatin. Meanwhile a second method, which is already in clinical trials in people with muscular dystrophy, uses antibodies to disable the protein.
    In 1997, researchers led by Se-Jin Lee of Johns Hopkins University School of Medicine in Baltimore, Maryland, engineered mice in which the gene for myostatin had been "knocked out". The animals grew muscles twice as big as normal. A defect in the myostatin gene was what caused a German toddler, whose story was widely publicised last year, to develop prodigious muscles.

  2. Registered User
    TheCrownedOne's Avatar
    Stats
    6'3"  215 lbs.
    Join Date
    Dec 2004
    Posts
    1,362
    Rep Power
    805
    Level
    30
    Lv. Percent
    16%
    Achievements Activity ProPosting Pro

    This is old news. Too bad follistatin isn't affordable, otherwise we'd be in business.
  3. New Member
    picasso's Avatar
    Join Date
    Jun 2005
    Age
    52
    Posts
    78
    Rep Power
    155
    Level
    8
    Lv. Percent
    38.19%

    Actually, that news was just released. The science may be old, but the news that drugs are now in the pipeline is new. What does follistatin have to do with it? Is that what they are referring to?
    •   
       

  4. Banned
    jomi822's Avatar
    Join Date
    Jul 2005
    Age
    33
    Posts
    2,419
    Rep Power
    0
    Level
    35
    Lv. Percent
    52.43%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by picasso
    A defect in the myostatin gene was what caused a German toddler, whose story was widely publicised last year, to develop prodigious muscles.
    what story is this? i cant find it but it sounds interesting. Id like to find my myostatin gene and knock it out of the picture
  5. Board Supporter
    foo.c's Avatar
    Join Date
    Mar 2004
    Age
    44
    Posts
    116
    Rep Power
    190
    Level
    10
    Lv. Percent
    81.58%

    ACVR2B

    Wonder how long before this is a research chem?
  6. Registered User
    TheCrownedOne's Avatar
    Stats
    6'3"  215 lbs.
    Join Date
    Dec 2004
    Posts
    1,362
    Rep Power
    805
    Level
    30
    Lv. Percent
    16%
    Achievements Activity ProPosting Pro

    Nice find, Foo.c!
  

  
 

Similar Forum Threads

  1. Replies: 3
    Last Post: 03-19-2010, 06:31 PM
  2. Replies: 10
    Last Post: 02-12-2009, 07:29 PM
  3. Best for holding on to muscles during a cut
    By LCSULLA in forum Supplements
    Replies: 77
    Last Post: 10-10-2008, 07:10 PM
  4. Replies: 1
    Last Post: 04-21-2004, 02:31 PM
  5. DMSO as a useful adjunct to muscle hyperplasia
    By Dwight Schrute in forum Anabolics
    Replies: 4
    Last Post: 01-02-2004, 07:52 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in