Genova metabolic results

[LeanGuy]

I have completed a Genova metabolic test, as suggested by JanSz. I was hoping it would provide some clues to my insomnia and low serotonin, however most seem in range. I know its weird to be bummed when your tests come back normal JanSz, what do you think?

[The Matrix]

I have completed a Genova metabolic test, as suggested by JanSz. I was hoping it would provide some clues to my insomnia and low serotonin, however most seem in range. I know its weird to be bummed when your tests come back normal JanSz, what do you think?

Body is not converting to FAD the active form of b2
need to use converted form of b2 and it should help alot of issues. Also looks like undermethylation as well since dopamine and serotnin levels are at the low end. Kreb cycle gets going but it fizzles out at the end. Are you expierencing alot of joint paint. YOu may need malic acid supplement to help feed into it where it is left off.

[LeanGuy]

Body is not converting to FAD the active form of b2
need to use converted form of b2 and it should help alot of issues. Also looks like undermethylation as well since dopamine and serotnin levels are at the low end. Kreb cycle gets going but it fizzles out at the end. Are you expierencing alot of joint paint. YOu may need malic acid supplement to help feed into it where it is left off.

Thanks for the response. I do get achy joints sometimes. So... should I take extra B2 (is there a special active kind?), methionine/sam-e, malic acid? My doctor didn't really give me any suggestions-- just said its not too bad and not to worry.

[MacDonnell]

LeanGuy,

Did you get the Genova test done through your doc, or did you just do it on your own? Btw, your results DO look pretty good - You should be fairly happy with them!

Mac

[LeanGuy]

LeanGuy,

Did you get the Genova test done through your doc, or did you just do it on your own? Btw, your results DO look pretty good - You should be fairly happy with them!

Mac

I got it from my doc, but you can get them yourself here:
Welcome to Integrative Psychiatry Mental Health Testing and Treatment (a doctor-run site)

Yeah, I am glad the results are ok, but I was hoping for an answer as to why I can't sleep!!

[The Matrix]

Thanks for the response. I do get achy joints sometimes. So... should I take extra B2 (is there a special active kind?), methionine/sam-e, malic acid? My doctor didn't really give me any suggestions-- just said its not too bad and not to worry.

I would need to do further evalution from a clinical stand point examinng lifestyles, blood work , dietary and supplmemntation interventions. Sleep problems are simple lifestyle changes as well as identifying the cause to way you can not sleep which is evident in your metabolic panel., I bet your wife sleeps like a baby..

[LeanGuy]

I would need to do further evalution from a clinical stand point examinng lifestyles, blood work , dietary and supplmemntation interventions. Sleep problems are simple lifestyle changes as well as identifying the cause to way you can not sleep which is evident in your metabolic panel., I bet your wife sleeps like a baby..

Actually she has similar problems! I'll PM you.

[JanSz]

I have completed a Genova metabolic test, as suggested by JanSz. I was hoping it would provide some clues to my insomnia and low serotonin, however most seem in range. I know its weird to be bummed when your tests come back normal JanSz, what do you think?

Well what I think, you turnaround and get NutrEval test asap.
I am glad that you posted on this and not any other board.
On this board, nobody bothers people doing Genova testing, plus posts can be edited. I value editing capability.

I have excuse, I am learnig this stuff about Genova testing.
I did
Metabolic analysis
then
ONE
then
Fatty acids

finally I will do my NutrEval on May22/08
But I am posting my experience so others can learn from it.

You have no excuse, specially now when you have a doc who deals with Genova.
-----------------
You have not posted the whole test, add/edit the missing pages.

On my page #5 there is
Interpretation at glance

table with three columns.

If you are going for NutrEval, do not use any supplements, vitamins, minerals or additives or anything 2 -3 weeks before test.
you want to see what you body does on its own, without any help, just plain food + water.

From NutrEval test you will get clean list of any supplements that you may need.

That will be fine for you.
If you get in touch with HAN, you will get aditional expert opinion on details, like you see, he already picked up same possibility in vit B2 area.

There are versions of same supplements that work better in some situations.

.
On page #5 of your report, you see:

J. Relative need for Riboflavin 5 - 50 mg/d
the mark is on 4

so your need for supplementation is 40%
maximum supplementation they consider 50mg/d

When mark is
0-3 no need to supplement
4-6 mild defficiency
over 6 high defficiency

You are not really supposed to look at that page (sort of),
their opinion about you is summarized in the table: Interpretation at glance.

.............................. .............................. .............................. ...........................
Well, your neurotransmitters are within ok area, but still they have overal grade #3, so you are missing tiny bit there.

Catecholamine Metabolites
Homovanillic Acid (HVA)
(HVA = dopamine metabolite)

Low

Suspect

Possible low precursors or neurotransmitters
(phenylalanine,
dopamine, DOPA, norepinephrine);
possible low cofactors (B2, B3, B6,
Mg, or Fe); possible impaired
methylation

L-tyrosine & B6, generally good response to NE reuptake
inhibitors (e.g., imiprimine); consider B2, B3 or
Fe (if low); support methylation (methionine or
SAMe, B6, B12, folate, Mg)

-----------------------------------------------------------------



.Good luck.
.

[LeanGuy]

You have no excuse, specially now when you have a doc who deals with Genova.
-----------------
You have not posted the whole test, add/edit the missing pages.

Thanks for the response. I have attached the other pages.

My excuse for not getting Nut***** right away is not enough money, LOL

[The Matrix]

Thanks for the response. I have attached the other pages.

My excuse for not getting Nut***** right away is not enough money, LOL

I handle these test on a daily basis from people with CFS and other metabolic disorders. I was the one that sifted through all jansz blood work, ONE test and his supplementation program. Corrected his problems associated with BPH, got him off adex which people have deamed almost impossible, corrected the imbalances in with middle of the road recommendation based upon my own past expereinces which have composed of the most complex medical issues one can endure and even of come. Technically I am not suppose to even be here but I have come back from deaths door. My time is not over yet, but instead I was given a gift of comprehensive knowledge to help make a difference in peoples life..MY jouney has just begun..

[JanSz]

I handle these test on a daily basis from people with CFS and other metabolic disorders. I was the one that sifted through all jansz blood work, ONE test and his supplementation program. Corrected his problems associated with BPH, got him off adex which people have deamed almost impossible, corrected the imbalances in with middle of the road recommendation based upon my own past expereinces which have composed of the most complex medical issues one can endure and even of come. Technically I am not suppose to even be here but I have come back from deaths door. My time is not over yet, but instead I was given a gift of comprehensive knowledge to help make a difference in peoples life..MY jouney has just begun..

Right to the above, but..

Other than ONE I also had Faty Acid analysis,
so really what I was missing from NutrEval is

Elemental Analysis, Packed Erythrocytes (RBC's)

not only that, I am missing,
but also advice that come with complete test. That advice is not included in incomplete tests.


For anybody who reads this and would like to do this testing but is short of money:

wait

save money

then do the correct test.

The correct test is NutrEval.


.
.
Yes HAN helped me a lot,
on top of the advice I got with the tests.

It is since Mar30/08 that I do not use Arimidex/Anastrozole.
Wonder if that will continue.

Also urination urgency and frequency is easier to live with.

..


If possibe, keep Genova tests discussion on this board only.
Dr John told me to not discuss Genova on his board,
I have to listen to his request to be able to learn from his wisdom.
.
http://www.matrixnutritionandfitness...8&postcount=26
.
.
.

[JanSz]

Thanks for the response. I have attached the other pages.

My excuse for not getting Nut***** right away is not enough money, LOL

Well, just read your report.
Look at what they sugest you do, page 7 & 8.
You are also eating some funny supplements that cause problems, change DL-fumaric or DL-mali acid supplements to L-forms.

L-phenylalanine 500-2000 mg/d
L-tyrosine 500-2000 mg/d
L-methionine 500-1000mg/d
Magnesium 100-200 mg/d
Detoxification (well first you have to confirm that you need it by RBC elememt analysis, they suspect that you may have some toxic substances to get rid of)
Molybdenum 50-250 μg/d,
B2 5-50mg/d (riboflavin)
.
.
Well three more item to clarify, Pyruvic, Lactic & Malic acids.
I buy all of the above stuff from LEF.org


Man, you have got a full plate, make correction to what you now know, save mone for the next test in 3 -4 months.

I am stopping all my supplements for over 2 weeks, going for my NutrEval.
Sort of a semi-clen slate approach.
.
.
Just look what happened when you posted (only) list of results.
Well, very little happened.

This is what you would get (and did) from you doc or other people, do not hold it agains him, you are lucky, he facilitated the test for you.

But Genova have given you their opinion, rather long list of actions.

It will get better when you do NutrEval.


Good luck.
.
.

[LeanGuy]

You are also eating some funny supplements that cause problems, change DL-fumaric or DL-mali acid supplements to L-forms.

Thanks for the review. I don't understand this, I'm not taking anything too weird:

Multi Vitamin/Mineral
Vitamin C 2000mg
Pantothenic Acid 2000mg
Zinc 30mg
MethylCobalin B-12 (sub) 1mg
Sam-E 400mg
Rhodiola 500mg
CoQ10 100mg
EPA/DHA fish oil 1000mg
Nettle Root 500mg
Maca Root 6000mg
Stoked (Resveratol, Quercitin, Icariian) 800mg
Trib Test Extreme (rotated with Stoked) 500mg
L-Tryptophan 1000mg
L-Lysine 500mg
Probiotic 100mg
DHEA (sub) 50mg

[JanSz]

Thanks for the review. I don't understand this, I'm not taking anything too weird:

Multi Vitamin/Mineral
Vitamin C 2000mg
Pantothenic Acid 2000mg
Zinc 30mg
MethylCobalin B-12 (sub) 1mg
Sam-E 400mg
Rhodiola 500mg
CoQ10 100mg
EPA/DHA fish oil 1000mg
Nettle Root 500mg
Maca Root 6000mg
Stoked (Resveratol, Quercitin, Icariian) 800mg
Trib Test Extreme (rotated with Stoked) 500mg
L-Tryptophan 1000mg
L-Lysine 500mg
Probiotic 100mg
DHEA (sub) 50mg

You may want to involve HAN.
Possibly what you are eating have DL without specifying it.


You should have stopped all supplements for (2 weeks or a month) before going for that test.
Now we are guessing.




Look at page #2 item #25
Fumaric Acid is very low, on the bottom.

Fumaric Acid
(Metabolite of succinic acid,
precursor of malic acid); also
produced during urea cycle and
formed from phenylalanine and
tyrosine)

Page #1 item # 14 Vanilmandelic Acid (VMA) low, red (below low range)
Page 1 item #16 MHPG is low, on green but low.
Suspect
Possible low precursors or neurotransmitters
(phenylalanine,
dopamine, DOPA, norepinephrine);
possible low cofactors (B2, B6, Mo,
Cu, or Fe); possible impaired
methylation (if MHPG also low)


.
.

[LeanGuy]

You may want to involve HAN.

Yeah, I am preparing a bunch of docs for HAN

[JanSz]

Yeah, I am preparing a bunch of docs for HAN

Good move.

HAN does not have Excel capabilities.
So I am sending him screen captures of my spreadsheet, not easy route.

I just thought of using Google spreadsheet and documents capabilities.
If that would work, it would be much easier to communicate.

I did not tried this yet, myself.
I imagine that you may complete your stuf on your own Excel then copy paste to Google's spreadsheet, then publish it.
Off hand Googles spreadsheet looks different and less capable or possibly just takes time to learn it.

.
Post on your progress, if anything, I want to learn.
.
.

[LeanGuy]

I printed everything to PDF.

I'll post back my results.

[jinxie]

I got it from my doc, but you can get them yourself here:
Welcome to Integrative Psychiatry Mental Health Testing and Treatment (a doctor-run site)

Yeah, I am glad the results are ok, but I was hoping for an answer as to why I can't sleep!!

For what it's worth, I went through the ringer in ascertaining what would help my sleep. It ends up, I have autonomic dysfunction, which causes adrenalin to flood my system based on the movement of my body. I now take Coreg (an alpha/beta blocker, to tame the adrenalin, and to reduce the lability of my BP and pulse) and a benzo (Klonopin, to help balance the autonomic system, particularly during sleep hours).

My strongest recommendation is to get a sleep study. That's a no brainer. I had 2 of them. As it ends up, the CPAP never did anything for me. But my primary issue is alpha intrusions, from surges of adrenaline at night. If you dont have insurance, the sleep study could be spendy.

Good luck and hang in there. I feel like I am finally seeing the light, having slept well for about 8 of the last 10 days, which is better sleep than I've had in a few years. I look a world better, and am feeling better as well.

Best,
J

[JanSz]

I got it from my doc, but you can get them yourself here:
Welcome to Integrative Psychiatry Mental Health Testing and Treatment (a doctor-run site)

Yeah, I am glad the results are ok, but I was hoping for an answer as to why I can't sleep!!

Loks like some Genova tests can be ordered by that site, directly thru internet, without need to see doctor.

I see there Metabolic Analysis Profile
Metabolic Analysis Profile (Urine) by Genova Diagnostics
but I cannot find NutrEval

There is also a Specracell test that HAN is so fond of.

But it look like any test can be ordered:
Laboratory Diagnostic Tests

Quote:
If there is a test that you are interested in please call or email our office, chances are we can
order it for you.

---------------
Wonder if they help with insurance filing if the test is ordered thru internet?

.

[LeanGuy]

Loks like some Genova tests can be ordered by that site, directly thru internet, without need to see doctor.

A little expensive, but yes I love the site!!