Clomid and Armidix
- 05-06-2008, 11:26 AM
Clomid and Armidix
Urologist wants me to switch temporarily from test-e 100mg/week to Clomid or HCG because I am trying to have a baby with my wife. While on test I was not producing any good sperm as would be expectect. Note - He wants me off test-e completely for a while!
He wants me to preferably try Clomid and get another biopsy in 3-4 months. If sperm is present then I would have a vasectomy reversal.
My questions are:
1. how much Clomid is typically scribed?
2. while on test my E2 fluctuated between 55-66. Should I take Armedix while on Clomid? If so how much?
3. Why is Clomid being prefered over HCG? Both a world renown Urologist "Irwin Goldstein" and a fertility and urologist specialist last week suggested I switch to Clomid?
4. Test has almost eleiminated my depression and bi-polar. I was on 5-7 meds for them when I 1st started test-e July 07 and am down to low doeses of 2 now. I use to miss a day or 2 of work every couple months cuz I couldnt get out of bed. I haven had a depressive episode since being put on TRT. My urologist is worried about the depression thing too because my life has improved so much. How would Clomid effect this.
- 05-06-2008, 02:29 PM
Your depression and bi-polar reinforces my opinion.
Stay on TRT.
Load up on HCG
Check you sperm situation 4 months latter.
At that time add HMG, recheck in another 4 months.
You have too much to loose by going of TRT.
You already have 2 children.
Watch and keep adjusting your E2, more often than usual.
With Clomid you would newer know your e2 status.
If not for your 2 children I would understand your drive.
I have a friend, a girl, she is already after 2 divorces.
She is allergic to most of sperms, get pregnant them miscarries.
She also belives in family values, would not have a sex unless with husband.
With that she is desperate to have her own baby.
Girl is very smart, educated, pretty and fit.
Life is a lottery.
Look at this new post, thank you random987:
TRT & Fertility: A Good Website
Cancer News Content: Testosterone replacement therapy: Minimizing its impact on fertility
look at chart on the right:
just go by bottom four boxes.
Treat with HCG 2000iu 3x weekly
If no pregnancy, consider HMG(75iu 2-3 times weekly)
Continued failure consider testis biopsy
I would add to that, just for you and your depression and bipolar problems, skip the firs two steps that are described there.
But add good e2 control (if really neccessary).
Coviello and co-workers performed a dose-response study comparing various doses of concurrent injectable hCG while continuing injectable testosterone replacement in men.18 These authors demonstrated that hCG in this setting protected the testes from declining intratesticular testosterone concentrations while patients continued to use testosterone replacement therapy. This regimen may be useful for men with profoundly low testosterone levels or for those concerned about withdrawal symptoms from cessation of testosterone replacement.
05-07-2008, 12:19 AM
Check your B12 levels.
Better yet keep on taking a lots of Methy-B12 and some folic acid.
Just in case. Cannot overdose on B12.
[Clinical experience with methylcobalamin (CH3-B12) for male infertility][Article in Japanese]
Isoyama R, Kawai S, Shimizu Y, Harada H, Takihara H, Baba Y, Sakatoku J.
CH3-B12 was administered daily (1,500 micrograms/day, for 4 to 24 weeks) to 26 infertile male patients who visited our clinic from January to December, 1982. It was not administered, however, to patients with azoospermia. Semen analysis was conducted from 8 weeks after the administration of CH3-B12. Sperm concentration increased in 10 cases (38.4%), total sperm counts increased in 14 cases (53.8%), sperm motility increased in 13 cases (50.0%) and total motile sperm count increased in 13 cases (50.0%). Semen volume, however, could not be evaluated due to wide variation. Serum LH, FSH and testosterone were unchanged. Judging by our criteria, 11 cases (42.3%) improved, 11 cases (42.3%) were unchanged and the remaining 4 cases (15.4%) had aggravated.
PMID: 6485962 [PubMed - indexed for MEDLINE]
05-07-2008, 09:06 AM
I would prefer to stay off scripts for E2 in I can but my test results over the last year have my E2 in the 55-66pg/ml range. I have read a little about different supplements that might help but I have never seen any evidence with me that any supps work. I am taking L-Dex at this point.
Dont know what these mean or why I have these but at my last Dr. appt. (endo) I was told I was low in vit D and to take 2x 1000mg tabs/day. Also whatever Ferritin in mine was only 14ng/ml (range 24-336).
I do have high hemoglobin and get phlebotomies done to remove blood wheather or not that plays a role?
The only new issues I have is stomach issues and extremely tired all the time. Similar feeling to prior to being diagnosed with hypothyroid. I sleept 14 house Monday and still was tired.
Like to hear more on the B-12.
05-08-2008, 10:58 PM
05-11-2008, 02:44 PM
A. Selenium requirement during pregnancy has been difficult to measure in farm animals. However, recent research with rats show that there is a considerable transfer to the fetus via the placenta. This could be the reason that subsequent fertility is often impaired in marginally selenium deficient livestock.