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HCG not restoring ball size.

  1.  02-28-2008  10:41 AM
    Registered User Bungloid48's Avatar
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    HCG not restoring ball size.


    Hey guys,

    I'm a 19 year old on 150mg T enanthate weekly.

    I've been doing HCG for nearly a month now. I've tried everything from 500IU a week to 1,000IU a week (split into 2 days as per the Crisler protocol) and it has not made a single difference in my ball size or my well being.

    I was on T for a couple of months without the HCG and the atrophy was minimal although my load was somewhat decreased (no doubt I had a decreased sperm count as well but that does not concern me right now).

    Anyway, as time went on the atrophy got a bit worse as we bumped from 100mg of T to 150mg (although libido, wellbeing, strength and everything else good went up). My balls have lost a bit of size but still look like a perfectly normal pair.

    Thing is, HCG hasn't restored them to their previous size, which concerns me. I think it has helped increase my load a bit, but that's about it.

    At 70$ a month, that's quite an investment to be making for such little benefit.

    I'm going to see a *real* specialist that will fix me right up, but that's only in a month.

    Any ideas on what could be going on here? I didn't actually see the bloodwork results that were done after being 1.5 months on T but my endo assured me that everything looked good (high T, normal e2) but that's all he said. No bloodwork was done after starting the HCG, unfortunately, and maybe that's something I should do.

    No issues with gyno whatsoever so I doubt my E is causing me much trouble.... but you never know.



  2.  02-28-2008  10:43 AM
    Registered User Gutterpump's Avatar
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    Are you primary or secordary?
    How are you storing / reconstituting your hcg?

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  3.  02-28-2008  11:46 AM
    Registered User Bungloid48's Avatar
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    Originally Posted by Gutterpump View Post
    Are you primary or secordary?
    How are you storing / reconstituting your hcg?
    Secondary.

    With the first box of HCG I got, at room temp, I just used a 20 gauge needle and syringe, took all the sterile water out of the first vial, ejected that into the vial with the powder and shook it a little bit, and immediately stored it in the fridge. In fact, I do all my HCG injections with the fridge door open for fear of the vial's temp dropping.

    With the second box of HCG (I got that one yesterday), I did the exact same thing with the sole difference that I first put both vials in the fridge so that the sterile water would already be cold before mixing.

  4.  02-28-2008  03:18 PM
    The horror colkurtz_spf's Avatar
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    Originally Posted by Bungloid48 View Post
    Secondary.

    With the first box of HCG I got, at room temp, I just used a 20 gauge needle and syringe, took all the sterile water out of the first vial, ejected that into the vial with the powder and shook it a little bit, and immediately stored it in the fridge. In fact, I do all my HCG injections with the fridge door open for fear of the vial's temp dropping.

    With the second box of HCG (I got that one yesterday), I did the exact same thing with the sole difference that I first put both vials in the fridge so that the sterile water would already be cold before mixing.
    I read at drugs.com that HCG should not be shaken. Swirl it and let it dissolve. Don't worry so much about the temperature. As long as you keep it refrigerated it should be OK. There's no point to pre-cooling the BA water. You know it's going bad when it turns cloudy. Inject using a 30 gage insulin needle. If you are mixing the entire 10 ML vial of water 50 units will equal 500 IUs.

  5.  02-28-2008  05:53 PM
    Registered User Bungloid48's Avatar
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    Originally Posted by colkurtz_spf View Post
    I read at drugs.com that HCG should not be shaken. Swirl it and let it dissolve. Don't worry so much about the temperature. As long as you keep it refrigerated it should be OK. There's no point to pre-cooling the BA water. You know it's going bad when it turns cloudy. Inject using a 30 gage insulin needle. If you are mixing the entire 10 ML vial of water 50 units will equal 500 IUs.
    Yup. So the only possible explanation thus far is that I ruined it by mildly shaking it?

    The solution isn't cloudy at all. It's clear as water.

  6.  02-29-2008  05:26 AM
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    where did you get the HCG? **not asking for source** Do you know it is legit? Pharmacy? Pregnyl?

  7.  02-29-2008  07:02 AM
    The horror colkurtz_spf's Avatar
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    Originally Posted by Bungloid48 View Post
    Yup. So the only possible explanation thus far is that I ruined it by mildly shaking it?

    The solution isn't cloudy at all. It's clear as water.

    It gets cloudy after time, or if it's been unrefrigerated. Shaking it would leave it clear, but possibly destroy its structure. I didn't think it mattered until I read otherwise. Pistonpump is correct in questioning the source. Another thing to consider is that your dose may be too low - at least for now. You may want to double it.

  8.  02-29-2008  07:07 AM
    Registered User Bungloid48's Avatar
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    Originally Posted by colkurtz_spf View Post
    It gets cloudy after time or if it's been unrefrigerated. Shaking it would leave it clear, but possibly destroy its structure. I didn't think it mattered until I read otherwise.
    Damn, why isn't there a more clear warning not to shake the contents like GH has plastered all over the place? Does not make any sense. So is this 150$ down the drain?????

    It's legit HCG from the pharm. I got a script. The only size they have is 10,000IUs. Search for "phatkid pharmacy" thread for pics. I'm using the exact same brand and size as he is. Maybe he can chime in...

  9.  02-29-2008  07:09 AM
    Registered User Bungloid48's Avatar
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    Originally Posted by colkurtz_spf View Post
    It gets cloudy after time, or if it's been unrefrigerated. Shaking it would leave it clear, but possibly destroy its structure. I didn't think it mattered until I read otherwise. Pistonpump is correct in questioning the source. Another thing to consider is that your dose may be too low - at least for now. You may want to double it.
    I've thought of doubling it. It wouldn't be a problem. But what about the whole "leydig cell desensitization" thing? That's what shyed me away.

    What dosage should I try that is within the safe range? Obviously, with 10,000IUs and a 30 day shelf-life, I can experiment with some large dosages.

    Thanks.

  10.  02-29-2008  07:46 AM
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    i havent seen much ball size improvement either. i do 300iu 2x a week.

  11.  02-29-2008  09:09 AM
    The horror colkurtz_spf's Avatar
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    Originally Posted by Bungloid48 View Post
    I've thought of doubling it. It wouldn't be a problem. But what about the whole "leydig cell desensitization" thing? That's what shyed me away.

    What dosage should I try that is within the safe range? Obviously, with 10,000IUs and a 30 day shelf-life, I can experiment with some large dosages.

    Thanks.
    I've heard about leydig desensitization too. Let me tell you about my personal experience. My doctor had me on 10,000 IUs per week for two months and 8,000 for the next eight. The last two months I reduced to 4,000. During this time my total test never dropped below 1100 and free levels ranged from 250 to 425. I was using HCG as TRT and drew blood regularly to make sure other hormones were in balance.

    I stopped completely for about 8 months to try herbal alternativesthat didn't do the job and then decided to go back on. This time I reduced the dose to 2,000 IUs per week. On my last draw, after six weeks of use my total was at 957 and free at 233. It appears my leydig cells are in tact after a year of very heavy use. I don't necessarily recommend this for you. We are all different and I believe the advice and monitoring of a physician is required.

  12.  02-29-2008  09:55 AM
    Registered User Gutterpump's Avatar
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    I've tried 380iu twice a week while I was taking 5-6 sqrts of dermacrine daily. Kept em hangin low, but I didn't get a feeling of well being or a libido increase at all from it. I felt nothing immediately after injecting IM, nor later on in the day. I think my loads got a bit larger though. Nothing drastic mind you.

    Brand was organon pregnyl.

  13.  02-29-2008  11:59 AM
    Registered User JanSz's Avatar
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    Originally Posted by Gutterpump View Post
    I've tried 380iu twice a week while I was taking 5-6 sqrts of dermacrine daily. Kept em hangin low, but I didn't get a feeling of well being or a libido increase at all from it. I felt nothing immediately after injecting IM, nor later on in the day. I think my loads got a bit larger though. Nothing drastic mind you.

    Brand was organon pregnyl.
    What is the amount of liquid that you drew.
    I oppened second ampoule today.
    I got out 0.62cc
    Label says 1mL

    Powder says 1500iu

    I divided the liquid into 4 equal parts
    0.62/4=0.155=15.5units
    so hopefully each of shots will be
    1500/4=375iu

  14.  02-29-2008  12:15 PM
    Registered User Bob45's Avatar
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    If you are on T constantly you won't be producing on your own from what I understand. If you were off T and wanting and able to produce on your own then they would grow. Even with my LH and FSH high my left nut was kind of small. I've been taking Indolplex/Dim. It is getting back to normal now. I'm guessing my estradiol was keeping me from producing enough and it shrunk. How is your estradiol level?

    Also how was the size before? The hcg will keep you producing what you can I think but maybe you just aren't producing enough? I'm guessing and trying to learn myself. So don't take my posts and try anything different.

  15.  02-29-2008  12:33 PM
    Registered User JanSz's Avatar
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    Originally Posted by colkurtz_spf View Post
    I've heard about leydig desensitization too. Let me tell you about my personal experience. My doctor had me on 10,000 IUs per week for two months and 8,000 for the next eight. The last two months I reduced to 4,000. During this time my total test never dropped below 1100 and free levels ranged from 250 to 425. I was using HCG as TRT and drew blood regularly to make sure other hormones were in balance.

    I stopped completely for about 8 months to try herbal alternativesthat didn't do the job and then decided to go back on. This time I reduced the dose to 2,000 IUs per week. On my last draw, after six weeks of use my total was at 957 and free at 233. It appears my leydig cells are in tact after a year of very heavy use. I don't necessarily recommend this for you. We are all different and I believe the advice and monitoring of a physician is required.
    Great info, thank you.
    Do you happen to have BAT values, corresponding to TT & FreeT values?
    Better yet, if you could share complete info.
    TT
    FreeT
    BAT
    SHBG
    Albumin
    --------------------------------------
    From study and my post #63
    Jan's BloodTest April13/2007

    I see that 100% of HCG supply is 306iu/EOD
    306*7/2=1070iu/week

    It appears that 2000iu/week may be a safe dose.
    2000/7*2=570


    I will keep this in mind, I am using now 380iu/EOD
    that is 380*7/2=1330

    The Pregnyl 1500
    I may divide into 3 shots rather than current 4.
    ----------
    Using always fresh HCG never hurts.
    What is your experience in this area?

  16.  02-29-2008  02:25 PM
    The horror colkurtz_spf's Avatar
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    Originally Posted by JanSz View Post
    Great info, thank you.
    Do you happen to have BAT values, corresponding to TT & FreeT values?
    Better yet, if you could share complete info.
    TT
    FreeT
    BAT
    SHBG
    Albumin
    --------------------------------------
    From study and my post #63
    Jan's BloodTest April13/2007

    I see that 100% of HCG supply is 306iu/EOD
    306*7/2=1070iu/week

    It appears that 2000iu/week may be a safe dose.
    2000/7*2=570


    I will keep this in mind, I am using now 380iu/EOD
    that is 380*7/2=1330

    The Pregnyl 1500
    I may divide into 3 shots rather than current 4.
    ----------
    Using always fresh HCG never hurts.
    What is your experience in this area?
    My last draw was an interim (six weeks) to see how the HCG was working. The only results were the ones I posted:

    Total T - 957
    Free T - 233
    Estradiol 26

    I'm having a comprehensive panel done the middle of March. I'll post the results. SHBG will not be included as my doctor does not see the need, at least where I'm concerned. I've read about its importance in this forum and made mention to him. That's about as far as I will go. I have felt nothing short of great on his protocol, and figure if it isn't broken don't fix it.

    I normally split my dose 1000 IUs on Tuesday and 1000 IUs on Saturday (both in the evenings). A week ago I asked if I could split the Tuesday dose on Thursday (500 Tuesday and 500 on Thursday). I like the way it feels and I'm anxious to see the results. As for 2000 being safe I have no doubt. I did between 8000 and 10,000 a week for damn near a year without becoming desensitized. The main problem was estrogen. You probably remember the results I posted. For some reason the files have been removed. It was under “My Cenegenics Experience.”

  17.  02-29-2008  02:51 PM
    Registered User Gutterpump's Avatar
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    Originally Posted by JanSz View Post
    What is the amount of liquid that you drew.
    I oppened second ampoule today.
    I got out 0.62cc
    Label says 1mL

    Powder says 1500iu

    I divided the liquid into 4 equal parts
    0.62/4=0.155=15.5units
    so hopefully each of shots will be
    1500/4=375iu

    I take 1mL of solvent, reconstitute the hcg, move that to a sterile multi-draw vial. I then take 1mL of bacteriostatic water to dilute (inject down side of glass to mix lightly) and then place in fridge.

    so that's 1500iu / 2mL

    I take .5cc for each shot.

    Each shot then = ~ 375iu (same as yours)


    I've stopped taking HCG for the past week now. When I was taking it, I would also take 8-10mg aromasin ed. My joints were hurting a bit during workouts (wrists hurt) so I stopped that as well. My e2 was around 30 when last checked (before taking anything), wasn't too high, so I was likely taking a tad too much aromasin afterwards.

    Will likely be starting up HCG again, but maybe on an eod schedule. I may re-introduce around 4mg of aromasin, for a short while, take 2 months off and then re-assess before talking to dr john.

  18.  02-29-2008  04:24 PM
    Registered User Bungloid48's Avatar
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    What the hell is the point of doing HCG 250IU twice weekly then? Dr. Crisler claims it restores ball size in his patients and yet all I hear is people complaining that it doesn't do jack **** as such low dosages, and when you ramp it up, your estrogen levels skyrocket. I've even read of one guy getting suicidal depression from taking HCG.

  19.  02-29-2008  04:31 PM
    Registered User Gutterpump's Avatar
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    I wouldn't take other patient's recommendations per say. Best to consult with your dr and he will tweak as needed. Not everyone is the same, but there are guidelines Dr's may follow with people when they first start.

  20.  02-29-2008  04:55 PM
    The horror colkurtz_spf's Avatar
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    Originally Posted by Gutterpump View Post
    I wouldn't take other patient's recommendations per say. Best to consult with your dr and he will tweak as needed. Not everyone is the same, but there are guidelines Dr's may follow with people when they first start.

    Good advice. I wouldn't try any of this without the care of a physician. Everyone is different.

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