T Dosage and Age

[MarkLA]

Differences in the Apparent Metabolic Clearance Rate of Testosterone in Young and Older Men with Gonadotropin Suppression Receiving Graded Doses of Testosterone -- Coviello et al. 91 (11): 4669 -- Journal of Clinical Endocrinology & Metabolism

Suggests that due to reduced T clearance, older men may need a lower T dosage than younger men. The differences seem to be pronounced.

Mark

[JanSz]

Differences in the Apparent Metabolic Clearance Rate of Testosterone in Young and Older Men with Gonadotropin Suppression Receiving Graded Doses of Testosterone -- Coviello et al. 91 (11): 4669 -- Journal of Clinical Endocrinology & Metabolism

Suggests that due to reduced T clearance, older men may need a lower T dosage than younger men. The differences seem to be pronounced.

Mark

Note the doses used:

"125-, 300-, and 600-mg dose groups"

The results are probably correct, but rather irrelevant to what we are attempting to accomplish.

We adjust the dose until either FreeT or BAT gets to desired level.

If somebody metabolizes faster he will end up with somewhat higher T dose then slow-metabolizer.

It also happens that Phil is known fast metabolizer, he is 62yo.