Subcutaneous Testosterone Injection Question
- 01-02-2008, 01:49 AM
Subcutaneous Testosterone Injection Question
Hey guys.. I've been seeing more discussions about this topic lately. If you remember - last year - me and a few guys experimented with this for a very short time - and were basically talked out of doing it.
Has anything changed since then? Have sub-q test injections gained any new ground over the past 6 months or so? Or is this just more experimentation?
- 01-02-2008, 04:13 PM
BA- 31ga 5/16" long needle 3/10cc syringe
for either shot.
use 6" around navel for shots.
Newer had any problems, infections or anything.
Blood test shows TT as expected.
Estrodial as expected.
DHT as expected (on top of range)
I like the way it is.
Not going to change.
Overall rather skinny but I have a pound or two of fat around navel.
If someone have a paper thin skin in navel area, that is no fat whatsoever there,
the shot would then have to become under skin shot.
I would not shoot straight thru the stomach.
In that case I would rather switch to outside thigh area,
the skin is always paper thin there, but I would shoot straight 90 degrees, so the needle would go (tiny bit) into muscle.
Or upper outside quadrant of a buttock, straight no angles.
01-02-2008, 04:21 PM
Subcutaneous administration of testosterone. A pilot study report.
Al-Futaisi AM, Al-Zakwani IS, Almahrezi AM, Morris D.
Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman. [email protected]
OBJECTIVE: To investigate the effect of low doses of subcutaneous testosterone in hypogonadal men since the intramuscular route, which is the most widely used form of testosterone replacement therapy, is inconvenient to many patients. METHODS: All men with primary and secondary hypogonadism attending the reproductive endocrine clinic at Royal Victoria Hospital, Monteral, Quebec, Canada, were invited to participate in the study. Subjects were enrolled from January 2002 till December 2002. Patients were asked to self-administer weekly low doses of testosterone enanthate using 0.5 ml insulin syringe. RESULTS: A total of 22 patients were enrolled in the study. The mean trough was 14.48 +/- 3.14 nmol/L and peak total testosterone was 21.65 +/- 7.32 nmol/L. For the free testosterone the average trough was 59.94 +/- 20.60 pmol/L and the peak was 85.17 +/- 32.88 pmol/L. All of the patients delivered testosterone with ease and no local reactions were reported. CONCLUSION: Therapy with weekly subcutaneous testosterone produced serum levels that were within the normal range in 100% of patients for both peak and trough levels. This is the first report, which demonstrated the efficacy of delivering weekly testosterone using this cheap, safe, and less painful subcutaneous route.
PMID: 17143361 [PubMed - indexed for MEDLINE]
01-03-2008, 12:30 PM
So this is pretty good news.. I'm plenty content with IM injections but I'm not fond of the idea of running short on luck and ending up with an abscess and having a muscle cut-open 5 inches deep to drain it. HRT is something you do forever and I feel the chances of a major problem like this are much lower over the course of a lifetime with SubQ injections.
My doctor isn't a believer (yet) of SubQ - so I'm going to just go along with this and see what he says at my next blood test. Now does anyone know HOW MUCH is the max that can be injected SubQ on a daily or every other day basis? I'm guessing that my results won't be as good as IM unless I increase the dose a little bit.. How much CAN be absorbed this way?
Thanks in advance...
01-03-2008, 12:50 PM
I'm also not sure on whether SubQ is safer. I'd like to hear more on this. Obviously muscle is a deeper injection, but do people really have the same number of infections with muscle vs. Subq?
01-03-2008, 01:04 PM
I dont buy into SubQ as safer either. Most abscesses and problems with IM shots are based on:
1. infection from sanitation issue where a foreign agent is introduced into the body via the IM injection
2. the viscosity of the oil or the solvent used in the oil
Both of these problems can occur with SubQ method of injection. People can get abscesses and infections from a SubQ shot if they do not use proper sanitary precautions. I specifically had a problem when I did not inject deeply enough into the muscle (I think the oil leaked out) and it led to what looked like an abscess right under the skin. Eventually with lots of heating pad time, the oil absorbed and the bruising went away.
But in my opinion, an abscess is MORE likely to occur with a SubQ shot of Test b/c the viscosity of the oil makes it ill-suited for that method of absorption.
01-03-2008, 01:32 PM
In regards to abscesses, I'd prefer to have one just under my skin (easy removal) as opposed to having one deep within a muscle. Especially in a glute, as I sit down most of the day while working (and then of course, most of the night while relaxing).
I also feel that if you need to cut open a muscle to remove an abscess, you'll be out of the gym a lot longer than if one needs to be removed just beneath the skin.
01-03-2008, 01:36 PM
01-03-2008, 05:07 PM
I want to inject only as much as neccessary to keep my
I do E2D shots and test on the day of the shot, blood drawn before the shot.
For long time user, gage size of a T shot using Quest Diagnostic test:
Testosterone, Free, Bio/Total (LC/MS/MS)
Quest Diagnostics: Test Menu
For someone just starting I would use good approximation for initial dose, using SHBG level.
Table on my post #40 here:
Jan's BloodTest April13/2007
for example someone with
150 1058 24.5 300 x35.6 250
would use 150mg/week
that dose have to be splitted to E2D schedule
say using 200mg/mL test
he would use
BD 31ga 5/16" long needle 3/10cc insuline syringe
and draw 21.5 units
Using this syringe and E2D schedule one can get max dosing of
he would have to have SHBG=48 or in vicinity
to justify this dose
210 1397 xx48 300 x61.5 250
01-07-2008, 05:23 PM
My endo conducted the study quoted on top. Since then they have had all their patients on Sub-Q in quebec. It is the new standard. I've been doing it for a couple of months myself and other than a bit of itching a a tiny bump that lasts for a week or so, there are no problems. It is deeeeefinetly safer than IM by a long shot. It's also completetly painless.
01-07-2008, 06:07 PM
Thank you for the reply. I remember with my experiment last year that I had the same results - just no bump. The area was a little pink and itchy for a couple of days. No big deal. This SubQ method is really going to bring TRT into the mainstream... 99.9% of the people don't like the looks of inch and a half needles - nor do they have what it takes to stick it into themselves..
01-07-2008, 06:45 PM
01-08-2008, 10:17 AM
01-08-2008, 07:44 PM
Last Friday I got B12 injection at doc's office.
He whipped humungous syringe, probably 25Ga 1.5" needle.
I am not saying that the shot hurt, it did not.
But that was cyano-cobalamin.
I want methyl-cobalamin.
Today it arrived from compouning pharmacy.
I used 30Ga 1/2" long needle 1cc syringe.
Used my trusty pincushion, around navel.
Went like a charm.
Hate to stick nails into my body, if I do not have to.
Methyl-cobalamin have to be kept cold, shelf life 30 days.
2- 5mL vials $55 + $19 shipping (in a cooler with ice).
I will have to check my local compounding pharmacy,
possibly I could save at least on shipping.
01-09-2008, 08:11 PM
Alright, against my better judgement I will use Subq for my next shot rather than IM.
If I die, who should my heirs send the police to see? :-)
09-28-2008, 07:53 AM
Bumping up something old.
My buddy started prop and he went subq. He used a regular slin pin. He pushed 100 IU (1 ml) and said he has a bump around the injection the next morning. (which will go away I assume)
I will report back to let you guys know.
09-28-2008, 08:39 AM
09-28-2008, 11:39 AM
Could this make the prop last longer then?
Maybe I couls suggest him pinning 50 IU ED instead of doing EOD at 1ml (which is too much for 1 injection site subQ)
Am I heading in the right direction here?
09-28-2008, 12:39 PM
09-29-2008, 03:15 PM
For those of you who have done this, where else did you inject besides the area around the naval? Are there any other areas that are acceptable? I would think the slower absorbtion of the oil would force you to rotate sites frequently. I would also think a better choice would be E or C instead of P b/c of the higher mg per ml concentration.
09-29-2008, 03:21 PM
Looks like prop is a bad idea. The 3 pink spots are still there. Less apparent, but there anyways. IM is the way to go for this one..
09-29-2008, 09:38 PM
I've been injecting T cyp subQ for months. I use a 29g 1/2 and inject subQ at a 45 degree angle so there isn't any leakage. I inject every three days .27ml and my TT was 872 on injection day prior to the injection. It works fine and no pain. I inject in the outer thighs. Pinch an inch of skin, inject, remove needle, and then release the skin.
09-29-2008, 10:11 PM
Interesting, but 1 ml EOD is impossible with prop.. The lumps are still apparent, and not really elegant....
09-29-2008, 11:24 PM
Never tried that. I will say that any more than .5ml subQ will be a little uncomfortable. T cyp seems to work fine subQ in small doses. I'm just using it for TRT so my doses are never very high. I have no idea where the belly fat idea came from. It' a lot more comfortable in thigh skin. The bump goes away in about 10 minutes.
09-30-2008, 12:01 AM
for the safeness factor that was being discussed almost a year ago, just thought Id throw out there since I didnt see it..... your less likely to pin into a vein and have oil in your lungs if your pinning into a pinched layer of fat opposed to muscle that you cant even really see.
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