pregolone cream

[sidnee]

where can I buy a compounded cream?

 

[rick055]

where can I buy a compounded cream?

You would have to get a compounded cream from a compounding pharmacy.

But even though it's OTC, I still think you need a doctor to call it in.

I take 1 ml of a 10% cream or 100 mg transdermally a day.

 

[sidnee]

Ttttttt

 

[JanSz]

You would have to get a compounded cream from a compounding pharmacy.

But even though it's OTC, I still think you need a doctor to call it in.

I take 1 ml of a 10% cream or 100 mg transdermally a day.

Yes to the above, but I want to make some guessing here.

I just heard, I think it was here:

Invalid Link Removed
--------------
GS02m - Estrogen Metabolism: Modifying Risk in Clinical Practice
Conference: A4M Orlando 2006
Speaker: Patrick Hanaway, MD
April 9, 2006 5:00 pm - 5:40 pm
---------------
that women on TRT that use either oral (pills) or cream Progesterone,
have a problem with clearing estrogen metabolites.
They produce lots of them.

So the solution is to use progesterone in gel.
=======================================

I know, you are talking pregnenolone, but it may also apply.

I will dig some more, plus in few days I should have my Estroessence results.
There is when one see mess if not properly treated.
If I see something out of line there or even with out, next time I am ordering my pregnenolone as a gel.
Right now I just started new jar, 2 months supply.

Wonder if there are different gells?

I suggest buyng this $20 lecture, I am sure I am missing at least half of very good information.
Possibly we could have more inteligent discussion if couple of guys would read this.

 

[hardasnails1973]

Yes to the above, but I want to make some guessing here.

I just heard, I think it was here:

Invalid Link Removed
--------------
GS02m - Estrogen Metabolism: Modifying Risk in Clinical Practice
Conference: A4M Orlando 2006
Speaker: Patrick Hanaway, MD
April 9, 2006 5:00 pm - 5:40 pm
---------------
that women on TRT that use either oral (pills) or cream Progesterone,
have a problem with clearing estrogen metabolites.
They produce lots of them.

So the solution is to use progesterone in gel.
=======================================

I know, you are talking pregnenolone, but it may also apply.

I will dig some more, plus in few days I should have my Estroessence results.
There is when one see mess if not properly treated.
If I see something out of line there or even with out, next time I am ordering my pregnenolone as a gel.
Right now I just started new jar, 2 months supply.

Wonder if there are different gells?

I suggest buyng this $20 lecture, I am sure I am missing at least half of very good information.
Possibly we could have more inteligent discussion if couple of guys would read this.

Pregenolone IMO topical actually helps keep e2 in check due to helping it control DHT as well as converting to progesterone through the skin unlike orals do (or have not been determined yet )

 

[JanSz]

Pregenolone IMO topical actually helps keep e2 in check due to helping it control DHT as well as converting to progesterone through the skin unlike orals do (or have not been determined yet )

HAN
I am taking about way of getting the pregnenolone into our bodies.
I am not questioning if we need it or not (not yet, due to lack of knowledge).
----------------------------------------
Apparently (with women using progesterone) form of delivery makes big difference in their estrogene clearing.

pills
cream
gel

looks like only gel is ok.
----------------------------------------

I am just making wild guess, that possibly it is similar situation with pregnenolone.

Remember when I was using Androgel I was responding beatifully (average by the book).

When I changed to Tcream I went down hill.
========================================
Estrogene clearing means, that they produce tonns of first and second Phase

2-Hydroxyestrone
4-Hydroxyestrone
16α-Hydroxyestrone

2-Methoxyestrone
4-Methoxyestrone
Quinones

and do not have enough (chemicals, vitamins what not)
to process it and get rid of it.
=======================================
Some of this are in not big enoug quantity or quality:

Metabolism of Estrogen
Phase I
+ Major path (450)
+ Hydroxylation (C2, C4, C16)

Phase II
+ Glucoronidation
+Sulfation
+Methylation

Genomic diferences are reson for different speed reaction, %% of reactions and speed of

elimination of different metabolites.
Different genes = different outcome

Phase I
CYP450 1A1 --> 2OH
CYP450 1B1 --> 4-OH ---> (Quinones Phase II) (cancer)
CYP450 3A4/5 --> 16OH (cancer)

Phase II
COMT
GST
===================

 

[hardasnails1973]

HAN
I am taking about way of getting the pregnenolone into our bodies.
I am not questioning if we need it or not (not yet, due to lack of knowledge).
----------------------------------------
Apparently (with women using progesterone) form of delivery makes big difference in their estrogene clearing.

pills
cream
gel

looks like only gel is ok.
----------------------------------------

I am just making wild guess, that possibly it is similar situation with pregnenolone.

Remember when I was using Androgel I was responding beatifully (average by the book).

When I changed to Tcream I went down hill.
========================================
Estrogene clearing means, that they produce tonns of first and second Phase

2-Hydroxyestrone
4-Hydroxyestrone
16α-Hydroxyestrone

2-Methoxyestrone
4-Methoxyestrone
Quinones

and do not have enough (chemicals, vitamins what not)
to process it and get rid of it.
=======================================
Some of this are in not big enoug quantity or quality:

Metabolism of Estrogen
Phase I
+ Major path (450)
+ Hydroxylation (C2, C4, C16)

Phase II
+ Glucoronidation
+Sulfation
+Methylation

Genomic diferences are reson for different speed reaction, %% of reactions and speed of

elimination of different metabolites.
Different genes = different outcome

Phase I
CYP450 1A1 --> 2OH
CYP450 1B1 --> 4-OH ---> (Quinones Phase II) (cancer)
CYP450 3A4/5 --> 16OH (cancer)

Phase II
COMT
GST
===================

If a person is low in cholesterol (under 160) I would recomended pregenolone. Taking 50 mgs topical pregenlone a day i beleived help to keep my e2 in check with out armidex as well other varaibles where consitant. I stopped the preg and my e2 went sky high. With my cholestrtol at 120 I NEED IT FOR SURE other people may not..