- 10-18-2007, 11:42 AM
My compounding pharm says she can do a sublingual T and it would be a better option than injections (for E purposes). I'm currently on 150mg (15 g of T?) of compounded cream with some pregnenelone and DHEA mixed in as well as 300IU of HGC 3xweek. Blood tests haven't shown much of a jump.
9/17/07 results showed:
DHT 37.0 25-75 ng/dl
Total T 348.0 250-1100 ng/dl
Free T 104.4 35-155 pg/ml
FSH 1.5 1.6-8.0 mIU/ml
LH 1.7 1.5-9.3 mIU/ml
Estradiol 31.0 13-54 pg/ml
Progesterone 0.6 .1 - 1.2 NG/ml
gonadotropin releasing hormone 5.2 4.0-8.0 pg/ml
Overall I feel pretty good - energy good, ADD symptoms way eased but still the pesky libido issues...
I'm seeing my guy today - any quick recommendations?
- 10-19-2007, 01:33 AM
Bump...can't believe nobody is curious about a sublingual delivery system?
- 10-19-2007, 10:08 AM
Is the the buccal (sticks on your gum) thing or something else?
Any info on efficacy, safety?
How long does it take to absorb?
Note there's a difference between oral (bad for liver) and sublingual.
10-19-2007, 10:34 AM
10-19-2007, 10:35 AM
10-19-2007, 11:52 AM
Transdermals (if they work) will raise your DHT sky high.
Then you will have to buy story that such high DHT is good for you.
You already have a proof that what you are using does not work.
Do more tests.
For what to test look at post #44
Jan's BloodTest April13/2007
Your DHT is only in the middle of range, and you are already using T cream.
If on T shots you will have low DHT you may have to get DHT compounded cream (hard to get) or Androgel (expensive).
Your DHT may need watching.
10-19-2007, 06:34 PM
Buccal delivery does avoid first pass metabolism that oral doses go through, but as has been said the kinetics aren't good for testosterone in men by this route. The blood levels don't stay high enough for long enough. Dosing would need to be 3 to 4 times daily in most cases, even then I'm not convinced the patient would feel well. We do dose women buccally without problems, but the blood levels maintained don't need to be nearly as high.
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