What factors can cause a decrease in penile sensitivity? There is a thread over at MM about this, but there isn't a lot of info there.
Low test and/or high E2.
Even when my Test is high if E2 goes up, it kills Mr Happy. He turns into Mr Sad.
These values are part of these Quest Diagnostics tests.
Estradiol, Free, LC/MS/MS (36169X)
Testosterone, Free, Bio/Total (LC/MS/MS)
Dihydrotestosterone, Free, Serum (36168X)
I also make attempt to keep these in range:
Estrogens, Fractionated, LC/MS/MS (36742X)
Estrogen, Total, Serum (439X)
In an effort to get more information on my estrogens, I send out yesterday urine sample for:
Genova Diagnostics EstroEssence
The EstroEssence check the following 11 (eleven) indicators:
Estrone (24hr urine)Male 3.00-12.00 mcg/24 hr
Estradiol (24hr urine)Male1.50-6.00 mcg/24 hr
Estriol (24hr urine)Male 3.00-28.50 mcg/24 hr
2-Hydroxyestrone (24hr urine) 0.26-13.68 mcg/24 hr
2-Methoxyestrone (24hr urine) 0.34-9.03 mcg/24 hr
16α-Hydroxyestrone (24hr urine) 0.25-7.89 mcg/24 hr
4-Hydroxyestrone (24hr urine) 0.33-1.95 mcg/24 hr
4-Methoxyestrone (24hr urine) 0.40 0.20-1.60 mcg/24 hr
2-Hydroxyestrone/16α-Hydroxestrone Ratio (24hr urine)0.94-1.56 Ratio
2-Methoxyestrone/2-Hydroxyestrone Ratio (24hr urine) 0.11-4.00 Ratio
4-Methoxyestrone /4-Hydroxyestrone Ratio (24hr urine) 0.18-3.60 Ratio
============================== ============================== =============
The above are the most commonly look at indicators.
At one time dr Marianco have given a list:
The hormones that can influence libido directly or indirectly include:
3 Estradiol and other estrogens
9 Thyroid Hormones
13 Growth Hormone
etc.etc. (practically every hormone)
Of course, some have greater influence than others.
But all are involved in a tight mesh of function.
Abnormalities in one can permeate the entire system,
causing problems with the others.
On MM this is what they were saying
"As far as I understand it, erection not withstanding, or rather standing to attention, penile sensitivity is all about:
the right levels of histamine
high dopamine or oxytocin
not too high serotonin or NA"
I understand most of it, but the Histamine part is confusing.
Yep, and it's all tied together. Estrogen is tightly linked to serotonin and Testosterone to dopamine. Not sure about the others like prolactin or oxytocin. A tangled web we weave...
Jan's BloodTest April13/2007
I had E2 measured twice, both the same range (< or = 29)
the other =60
always something to make you think.
I was 40 when I found out I had low Testosterone my Total T was 120 I felt like crap and was very sick off work on sick leave. Yet I could still have sex everyday I read this a lot men will be tested and are very low yet there sex life is good.
I was on TRT for about 7 yrs. when I started losing penile sensitivity it took a lot of work to reach an orgasm. As time went on I got ED some bad ED and could not reach an orgasm. I was on a nose spray that lowed my histamine levels. I stopped useing it but no help.
I later found out my E2 Estradiol was very high from being on TRT. We treated this and when it came down my ED was much better and I was reaching an orgasm. The thing that came back that I lost yrs ago was night time and morning wood had lost this 35 yrs ago Dr. at the time told me I am getting old I 30 when I asked about this. High E2 mess's up Cortisol, Thyroid, Testosterone and many other hormones and chemicals in your body.
You have no Idea in the last 5 yrs how many men are told by there Dr.'s that you don't need E2 tested.
Yep, the sexual enhancement lube should be out shortly (just waiting on labels.)
Oral product is coming also, but waiting on a few ingredients from China.
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I got 100g, without it I dont think i would of ever cum during sex... wih my gf..
it works.. even if u only take 1-3grams for a few days before on the same day!!
still takes me 30 mins, but better than screwing for 2 hrs.. with no result!