- 02-10-2011, 02:04 AM
- 03-02-2011, 03:30 AM
03-02-2011, 05:36 PM
Where is your shbg?
I have patients e2 that are 40 and feel great
mine is 35 and I can screw like a rabbit. I think you are going to make matters worse
with e2 of 34 that can be easily manipulated through life style and proper nutrients balancing. I think u are making a huge mistake. If your shbg is 18-20 then fine but other wise you are just drawing strawls and grasping at anything potentially in making your pre existing condition worse.
03-02-2011, 09:52 PM
My lab sheet states the optimal estradiol (E2) range is 0.5-2.2 pg/ml. My E2 came back at 1.5. A lot of you have E2 levels that are way above the optimal range. Am I misunderstanding E2 ranges? Are E2 levels of 40 or more normal? When it comes to E2 levels, is lower or higher better?
03-03-2011, 03:22 AM
The Matrix I have been told on here that the E2 above 30 or ANY level above my sweet spot "whatever that is" will cause the decreased penile sensitivity and reduced orgasmic pleasure. Why are you harping on shbg? will that effect the sensitivity? I am still learning here. You are a doctor? Have you had patients with the sensitivity problem?
I value your input.
03-03-2011, 03:48 AM
When I was first diagnosed with low t I had severely reduced sensitivity in my whole lower pelvic region and almost no pleasure from orgasm. Both came back to about 85% of normal on 5 grams of androgel during the "kick" before my normal t shut off. Then the symptoms were back. After not getting high enough on 10g of androgel my doc brought it back down to 5 and started test cyp shots of 100mg a week. my sensitivity got back to about 50% then stopped. All my other symptoms disappeared within 2 weeks of my levels being normal. I am stuck here and have been for 4 months now. I am desperate and scared.
I went to the boston medical group and they did a vibration test on my penis and said the nerves were working. They did an ultrasound and said the bloodflow was good. I have no scar tissue that would interfere with sensation.
After turning to the net in desperation I saw PMgamer18 talk about his issues with sensitivity and ed. I checked and my estradiol was 40 on one test and 45 on another. It was 25 when I was on 5g of gel when I had a full blood panel. My only hope for now is to try to get it down to 25 again like PMgamer18 suggested and hope it works.
I tried with Femara 8 weeks ago and it obliterated my E2 now it is back above 30 so I want to try the 1/4 mg of arimidex.
Where does shbg fit into all this? please help me understand.
I apologize for the long post.
03-03-2011, 08:35 AM
shgb helps make e2 doe it's job. Higher the shbg more e2 your body can handl e lower shbg then lower e2 has to be. Pmgamer and I have known ech other for years and talk on the phone each week. Every one is different what works for one may not work for the other. Why you have to know what is right for your chemistry.
03-04-2011, 12:55 AM
I will ask my endo if I can test my shbg when I see him tuesday. I am so thankful I have the support of people on this post. Thank you The Matrix. Do you treat a lot of trt guys?
Do you agree that shbg and or E2 levels may be causing the sensitivity issue? Are there other things I should look for?
03-04-2011, 07:48 PM
03-04-2011, 08:36 PM
I am sick of my endo not knowing what he is doing. I am going to try a guy named Irwin goldstein he runs a sexual health clinic in Sand Diego. Have you heard of him?
I wish I lived near Dr. Crisler or you. I want to try hcg but my endo said its dangerous with no long term studies and should only be used if I want to have kids.
I can't wait to see if this new doc is better. He seems to pay more attention to the big hormonal picture from his site. I hope that is the case.
03-04-2011, 08:36 PM
03-04-2011, 10:04 PM
03-05-2011, 03:58 AM
03-05-2011, 04:03 AM
He won't admit he doesn't know what to do he keeps saying just wait and see it takes a while. After months of waiting I finally went on here out of frustration! He should admit he doesn't know what to do and refer me to someone who does. Ugh!
03-05-2011, 10:58 AM
30 drs and specialists
$70000 blown on chasing my tail and crazy online supplements which only gave me false hope because I was just drawing strawls. That is why I started studying human body like never before researching several thousands of hours studies various topics. I have 5 years of clinic expereince dealing with any kind of health related illness under an MD supervision. Everything that people have gone through on here I have been through and then some.
That is why I am here to help educate people so they do not waste years of there life making the same mistakes I made. If you have the option, bite the bullet and do what you have to do to get better. With out health there is no wealth. I have very extremely wealthy clients and money means crap when you can not enjoy it and can even have fun with your family. These moments are priceless..
Best piece of advice is never give up hope and keep believing because eventually it will manifest it self...Stay positive focus. There are alot of other people out there who have it alot worse then we have it, but some times we tend this and need to reflect on people that are dying of cancer and other deadly diseases. We complain about alittle ED or PE compared to how they are suffering..
03-06-2011, 04:24 PM
Thank you The Matrix.
This doctor is an editor and chief of the Journal of Sexual Health and seems to know his stuff. His receptionist says he looks at balances of hormones not just testosterone. He looks at E2, prolactin, shbg, calculates your bio available testosterone, looks at dht, and adrenal hormones that can affect sexual function. (My doc looked at these one time in the beginning then just looked at free and total t). Many men come to him on trt with ED or sensitivity/orgasm issues. She says he has helped many of them regain full function. If he doesn't work I am going to Dr. Mariano, the only reason I am not seeing Dr. Mariano already is he is so far away (7 hour drive). This guy is a 1 1/2 hour drive.
It is hard not to be depressed about this stuff. I am glad I have someone to message who understands. I am sorry you had to waste so much time and money on this.
Hopefully I won't have to repeat the experience, but we will see.
03-06-2011, 07:19 PM
03-06-2011, 10:29 PM
Not sure if he looks at the other things or root causes. I will know more when I see him. FYI I eat a balanced healthy diet, maintain a healthy weight and do weights and cardio 3 times a week at the gym. I also take a multi vitamin and mineral, calcium and omega 3 fatty acids every day. Not sure what else to do in this area.
03-06-2011, 11:10 PM
03-08-2011, 03:19 AM
I had a free 10 minute phone consult with this doctor today. I was on Prozac for 2 years and when I came off it my sensitivity and orgasmic pleasure did not return. That was what eventually lead me to get a blood test a year and a half later and found my total t was 300 on one test then 280 on another. I discovered I had low T and started this journey.
This doctor said he thinks I have post SSRI sexual dysfunction and that is why it won't come back.
He also said at 37 and still wanting to have kids testosterone is the wrong thing to give me. He wants me to use Clomid to stimulate my natural production. He said test over the long term might damage my ability to have kids. What do you guys think?
I am more confused than ever! Has anyone ever heard of Post SSRI sexual dysfunction?
03-08-2011, 08:06 AM
Clomid challenge is not a bad idea, to see if you are primary or secondary hypogonadism. Then go from there. That is the approach I would use if a patient would want to concieve before mocving on to TRT. If you are on TRT then hcg then test for sperm motility and count. If it is low then look to factors which may be causing it to drop. You be surprised of what can cause it drop like a rock. If sperm are low then add in HMG 75-225 ius a week then retest in 2-3 months.
03-08-2011, 01:16 PM
That is very helpful The Matrix I feel better about seeing this guy now.
Have you ever heard of Post SSRI sexual dysfunction?
They have a forum and they talk about reduced sensitivity and orgasmic pleasure like I have persisting after they come off the anti-depressants. What is frustrating is other guys on trt have the same symptoms on here when their E2 or prolactin or adrenal hormones are off.....even if they are in the "normal ranges".
03-08-2011, 05:21 PM
03-08-2011, 07:05 PM
03-13-2011, 06:16 AM
BTW the doctors name is Irwin Goldstein a well know sexual dysfunction expert. He runs a sexual dysfunction clinic in San Diego CA
03-13-2011, 12:27 PM
03-24-2011, 01:44 PM
03-17-2012, 01:36 PM
03-17-2012, 01:44 PM
I think I may have post ssri sexual issues. I was on Paxil for 8 yrs and that's when a lot of my hormones issues started. Right now when I have an orgasm I am so sensitive that I have to stop. It tickles if that makes sense..I think it's a prolactin issues
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