- 09-06-2007, 08:01 PM
Hello also to Dr. Crisler! (fellow Michigander)
I've been a "lurker' here for about a month...I've decided to finally register.
I'm in my 40's.....
I've been on TRT for a little over a year. I have to say it's made a big difference in my life but there is so much more I need to learn and I have a ton of questions.
I go thru my GP (a D.O.) great guy but I have been thinking of contacting Dr. Crisler also for consultation.
- 09-07-2007, 08:40 AM
Welcome Rocky.....ask away.... Theres lots of people here who can steer you in the right direction.
- 09-07-2007, 07:22 PM
Thx jaydee..and all.
I have to be honest..You guys with all your knowledge on this subject make my head spin. Especially JanSz. The man is a wealth of knowledge!
I feel like I should be wearing a DUNCE cap!
I've been on TRT for almost 17 months. I first started on Depo-Testosterone shots(once a week) then Testim for the last year after the first month of the shots.
I recently switched to Androgel and have found that it is alot better for me. I actually feel it within a half-hour after I apply it. I mean it is incredible! Only 5 gr. a day too. My beard is growing like crazy/libido thru the roof.
I have been only tested for TEST & FREE TEST levels at regular intervals ...and of course PSA levels initially. No E2/LH(Heck I never even heard of the term "E2" before coming here).
My latest T level was 820+ out of 1100.(taken last month)I feel great BTW!
I started, like most here, at a low 220 range.
I do know that Test does convert to Estrogen if not kept in check from my days lifting a few years ago. To combat this I take 6-OXO and ZMA everynight. It seems to be working great.
I'm going to my doctor next week with a printout of what blood tests I'd like done(I got it from here), but I don't want to piss him off. He's a great doctor. Question, How should I handle this?
09-07-2007, 08:09 PM
so he can have a nurse copy that list on his company stationary, then hi signs it and give it to you
(45seconds and you are out the door)
Otherwise you are asking him to do lots of writtings,
first, he is going to make excuses because he is lazy to write the thing
second, he is going to make lots of mistakes because hi is going to hurry.
(hour latter you are goinig to have wrong script no matter what)
Tx for kind words.
When I was on Androgel I did not need AI.
My DHT went thru the roof.
Not sure if that hurt anything, but it was on my mind.
I handle my infant grandson, I am on Depo-T now.
Works good for me.
You may want to check if
prescription compounded pregnenolone cream 100mg/1gram 1gram/day would make any difference for you.
It works for me.
09-07-2007, 08:37 PM
09-08-2007, 03:13 PM
09-09-2007, 01:32 PM
09-09-2007, 01:53 PM
I didn't bring up the other tests I'd like to have done but I will later. I did show him the supps. I take at night (6-OXO and ZMA) He did take a long interest in looking over the bottle of 6-OXO. I love 6-OXO! I use the ZMA to help keep my nuts from shrinking. This combo at night is incredible!
I'm going back in a few weeks..I'll email him the tests I'd like to have done beforehand...great advice and thx.
09-09-2007, 04:09 PM
Bodybuilding.com - Anti-Estrogen Products Listing! Find The Best Anti-Estrogen Supplements!
6-OXO is what is known as a suicide inhibitor of aromatase. This means that 6-OXO™ binds to the aromatase enzyme in a permanent and irreversible manner, rendering it inactive.
Here we use Anastrozole, contained in Arimidex or Liquidex
It loweres estrodial, E2.
When I was using Androgel my E2 was fine.
You may not need AI (or 6-OXO), driving E2 too much down is not healthy.
One may need AI when on Testosterone injections.
Injections of T (and ithink HCG) often raise E2.
There is no way to figure out your e2 levels by how you feel, need blood test.
09-09-2007, 07:21 PM
09-09-2007, 07:54 PM
09-09-2007, 08:05 PM
I don't want to push on him.
I never had a "complete" test done like I stated I wanted. I'm going to ask him in a few weeks.
You remind me of a lawyer I know..LOL. I can see TRT has done well with you my friend!
The PM was about 6-OXO BTW.
09-09-2007, 08:58 PM
09-09-2007, 09:12 PM
09-10-2007, 03:29 PM
09-10-2007, 04:15 PM
09-11-2007, 08:22 AM
09-11-2007, 11:04 AM
09-11-2007, 12:08 PM
09-11-2007, 09:54 PM
09-12-2007, 07:04 PM
Resveratrol has a whole lot of good things going for it, but the one we're most interested in has to do with estrogen. You see, resveratrol acts as a potent estrogen antagonist (while also acting as an agonist in some tissues, similar to the drugs clomiphene and tamoxifen).
In higher concentrations, it acts as an aromatase inhibitor. That means that it stops the body from whittling away at your Testosterone.
This is cool because if a substance stops Testosterone from being converted to estrogen or estradiol, it not only prevents the nasty effects of estrogen (loss of muscle and strength and accrual of body fat), but it increases your level of Testosterone, leading to additional strength and muscle!
What's equally important is that it won't cause your Testicles to go on vacation, i.e. shrink. The testicles don't get a signal from the pituitary to shut down because estrogen has been curtailed!
There's a lot of good data in animal models to back this up. Studies have demonstrated a resveratrol-fueled increase in Luteinizing Hormone and Follicle Stimulating Hormone (the pituitary hormones that signal the testicles to start producing Testosterone) that's 2.7 times greater than placebo.
Additionally, resveratrol caused a 76% increase in sperm count, all of this without any adverse effects. (1)
The aromatase inhibition is thought to occur through two mechanisms: reducing the expression of aromatase, as well as binding to the enzyme and preventing it from doing its dirty work.
And, unlike conventional aromatase inhibitors, resveratrol doesn't cause a decline in endothelial (blood vessel) function. In fact, it seems to improve it! (2-12)
And remember those nasty xenoestrogens I mentioned earlier? Resveratrol seems to occupy the receptor sites, or biological "parking lots," so that these xenoestrogens can't "park" in their spots. That's good.
MORE GOOD STUFF
While athletes should no doubt be excited about these Testosterone-increasing, estrogen-lowering effects of resveratrol, male and female Life Extension people have been all over this substance for other reasons.
An overwhelming amount of literature on resveratrol has demonstrated potent cardiovascular benefits, anti-aging effects, powerful anti-cancer effects, anti-arthritic, and neurological effects (e.g. potential benefits in treating Alzheimer's Disease). Many of these benefits seem to stem from anti-oxidative and anti-inflammatory effects as well as gene modulation. (13-21)
What the Life Extension people are most excited about, though, is that resveratrol might actually extend lifespan.
Remember those calorie deprivation people that believed you could extend your lifespan considerably by just munching on a ridiculously low number of calories each day?
Well, one proposed mechanism by which calorie deprivation can make you live longer is that it activates a protein called SIRT1 (sirtuin 1). Activation of this protein inhibits PPAR-gamma activity and this causes your body to burn fat.
It's not hard to imagine that having less fat might cause you to live longer, but remarkably, resveratrol activates this very same SIRT1 protein.
So even if you're not concerned with extending your life at this point, resveratrol can cause your body to burn fat.
Maybe you've heard of the "French Paradox" (and no, it has nothing to do with why their star soccer player would head butt a guy in the finals of the World Cup)?
It's the medical puzzle where certain populations (French and Greek) seem to experience a low incidence of coronary heart disease while eating a diet high in saturated fat. Epidemiologists have reasoned that it has to do with their daily consumption of red wine.
Well, many researchers have gone one step further and concluded that it was the resveratrol in the wine that was responsible for the French Paradox. (22-25)
This miracle substance has also been shown to have impressive anti-fungal and anti-viral properties, and may even protect the liver from excessive alcohol consumption or oxidative damage from taking too much acetaminophen. (26-39)
If all that wasn't enough, there's a good deal of data demonstrating that resveratrol is an extremely promising compound for the prevention and treatment of prostate cancer! (40-48)
So if taking Testosterone-boosting supplements has made you wary before because of possible prostate risks, resveratrol seems like the answer to your prayers."
Acts as both an estrogen antagonist and an aromatase inhibitor.
Increases Testosterone without causing testicular shutdown
Promotes blood vessel health and cardiovascular health in general
Exhibits anti-cancer effects, particularly anti prostate-cancer effects
Exhibits anti-aging effects
Promotes fat loss
Has anti-inflammatory properties
Acts as an anti-oxidant
Exhibits anti-arthritic effects
Shows anti-fungal and anti-viral effects
Acts as a liver protectant
09-12-2007, 07:04 PM
09-12-2007, 07:41 PM
Can you post the references (1) and (2). I'd like to read up more.
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