Control of High Estradiol Levels - Arimidex
- 08-16-2007, 07:40 PM
Control of High Estradiol Levels - Arimidex
The following was posted on the Hypogonadism2 forum and I was requested to post it here as well. I have been looking for solutions to high Estridol where total testosterone, free testosterone for both trough and peak are in the upper normal range. Following is the post:
My Testosterone levels are at 709 peak and 611 trough which is pretty good. I inject .75cc of DepoTestosterone weekly. Problem is that the Estradiol levels are around 100 at peak and only drop to around 70 at trough. Has anyone tried Arimidex to control the estrogen and what are the successes and side effecte. My libido is non-existent with the T:E2 ratio at about 7:1. Any advice. Thanks
A later post was added as follows:
My anterior pituitary shut down, or at least that was what all the tests indicated..no FSH, LH at all with Total T down in the 60 range. Cortisol levels were normal. I am also hypothryoid as well as hypopituitary. The testicles were atropying and went through cycles of swelling and pain. The Epiditimus had hardened from a vasectomy many years ago and was also painful at times. There was also some evidence of varicose vein in the scrotum.. All considered my urologist, and I agreed, felt bilateral orchiectomy was the best long term solution. I had been on HRT (TRT) for a couple of years
prior. Problem is that now the HRT drives the Estradiol level out of site. Excess of 100 on peak. Looking for solutions to get the estrogen under control and maintain a 600-800 range of Total T and usable Free Testosterone as well. Right now the estrogen is binding up everything. No libido, ED, and a host of other symptome indicitive of Testosterone v/s Estrogen imbalance. My ratio is about 7:1 and should be more like 30:1. Looking for solutions. Thanks
for your input.
- 08-16-2007, 07:44 PM
I do not buy into ratios and such. There is so much variability from person to person.
One thing we have to back up ourselves on is BW from healthy males aged 18 - 24.
They tend to have TT levels in the 600 - 800 range and E2 levels 17 - 25.
A good starting dose of arimidex is .25mg E3D. Use BW and feelings to adjust.
08-17-2007, 11:41 AM
You are injecting 0.75cc, how much testosterone it is?
If you are using Depo-Testosterone that is 200mg/mL
that may be a lot of testosterone, (150mg/week), and then your TT(709 peak and 611 trough ). That is very low for this much testosterone. You must then have very high SHBG, for all this to make sense.
Or you are using 100mg/mL testosterone, then your dose is too small. Questions, questions.
Do not worry about ratios.
Try to be very detailed, organize info as much as you are able into tables.
scan your reports and make attachments, or retype them into spreadsheet and attach,
all medications and supplements that you use, specify shedule of how you are using it.
Post your complaints and problems.
Post all yout blood tests within last 2 or 3 years.
Detailed name of test, number, units, ranges, name of laboratory.
Read my thread, if you are able, arrange for the complete blood test that I list on post #44
Jan's BloodTest April13/2007
Read some sticky's, say thise two:
Read some protocols on LEF:
The Life Extension Foundation: Disease Prevention And Treatment Protocols
Adrenal Disease: Online Reference For Health Concerns
DHEA Restoration Therapy
Dhea Restoration Therapy: Online References For Health Concerns
Diabetes: Online References For Health Concerns
Liver Degenerative Disease
Liver Degenerative Disease: Online Reference For Health Concerns
Male Hormone Restoration
Male Hormone Restoration: Online References For Health Concerns
Thyroid Regulation: Online References For Health Concerns
Le Magazine, July 2006 - Report: Metabolic Syndrome
08-17-2007, 05:08 PM
First of all, good luck with the surgery.
Just out of curiosity, with TRT would you still be able to have sexual relations afterwards?
08-17-2007, 11:05 PM
Life after surgery..
Yes, sexual relations continues as before. Had the surgery in 2005.
08-18-2007, 10:47 AM
Sorry I misunderstood the timing. I am glad things are sort of working out for you. I am new here too, and this definitely seems like a knowledgeable board.
08-18-2007, 11:04 AM
I started arimidex not long ago, theres no side effects at all. I feel a lot more clear headed, I can lose weight again, I feel more relaxed and happy in general. The only thing is it hasnt improved my libido, I think libido is sorted out with DHEA and Pregnenelone cream.
08-20-2007, 09:43 AM
Prior to this, I was on Androgel for several years, with not nearly the same effect. I dropped the Androgel 3 weeks before going on Arimidex. My doc believes that Arimidex at the same time as TRT is not a good thing, though I've never understood the logic. Whatever, his treatment regimen works very well for me.
This ought to work (Arimidex without TRT) on people whose gonads are producing an honest amount of T, but whose body is otherwise converting the T into E2. This would not work on anybody who is not producing T; e.g., primary hypogonadism.
08-20-2007, 12:19 PM
08-20-2007, 12:29 PM
08-20-2007, 03:20 PM
08-20-2007, 03:35 PM
08-20-2007, 03:52 PM
08-20-2007, 03:57 PM
08-20-2007, 04:53 PM
Bob thanks for coming and posting your use of Arimidex to keep your T levels up. So guys here is one that shows it can be done.
08-21-2007, 10:01 AM
08-21-2007, 10:21 AM
I know that a lot of folks use much less than 1mg/day of Arimidex, but aren't a lot of them also on TRT? I am not. My dosage is the one which was the subject of the leading study, and this is what my doctor has had good results with.
08-21-2007, 10:29 AM
08-21-2007, 10:56 AM
08-29-2007, 02:56 PM
Is there much we know - even anecdotally - about long term use of arimidex? Does it appear relatively safe for men?
08-29-2007, 06:47 PM
08-29-2007, 06:54 PM
08-29-2007, 07:00 PM
Pour over the hundreds upon hundreds of articles, studies and such that is going on like I did. Im not here to do all your work for you, I do enough for myself.
Resveratrol is one of if not THE most researched plant based compounds in the world right now, so finding info shouldn't be hard to do.
08-29-2007, 07:17 PM
08-29-2007, 07:20 PM
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