peabody
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I just received the result from my LEF/LabCorp standard E2 blood test. It was 48 pg/mL (0-53 for males).
I am not on TRT. I'm 55, 5'10", 170#. I'm quite fit, go to the gym every day, am moderately muscular, and have a flat tummy. Supplements include 16 mg of zinc per day. All the plumbing still works pretty well, but libido isn't all I would hope for. In the past I took a series of saliva tests that were consistent in showing quite high T levels (that would be free T), but also high E2 levels.
I believe the high E2 (assuming 48 is higher than ideal) is a result of taking a high dose of Diltiazem, a calcium channel blocker that works very well on my blood pressure. Diltiazem is a moderate inhibitor of 3A4 and other CYP's, and has a reputation of causing E levels to go up, I would guess by inhibiting their metabolism, in rare cases even causing gyno.
I understand that everyone would want to know current T and SHBG levels, but I only did E2 - I have to pay in full for whatever testing I do, and my pockets aren't deep. So if it's possible, I'd like to settle on a reasonable course of action to see if a lower E2 level might bring some improvement and make me a horny teenager again.
I have some 1/4 mg Arimidex tablets that I got several years ago from a Chinese gentleman named Josh, but never used. I though I would begin taking that, and then test E2 again. But take how much, and for how long?
How about - 1/16 mg dose, taken every other day, which would be roughly 1/4 mg per week. And then test again after maybe three weeks. But I have no idea how long it takes to reach a stable E2 state with Arimidex.
My plan would be to get E2 down to the low 20's, hoping that would get the job done. Does 1/4 mg per week sound like a conservative dose for someone not on TRT, at least a dose not likely to take E2 too low?
Any comments would be appreciated.
I am not on TRT. I'm 55, 5'10", 170#. I'm quite fit, go to the gym every day, am moderately muscular, and have a flat tummy. Supplements include 16 mg of zinc per day. All the plumbing still works pretty well, but libido isn't all I would hope for. In the past I took a series of saliva tests that were consistent in showing quite high T levels (that would be free T), but also high E2 levels.
I believe the high E2 (assuming 48 is higher than ideal) is a result of taking a high dose of Diltiazem, a calcium channel blocker that works very well on my blood pressure. Diltiazem is a moderate inhibitor of 3A4 and other CYP's, and has a reputation of causing E levels to go up, I would guess by inhibiting their metabolism, in rare cases even causing gyno.
I understand that everyone would want to know current T and SHBG levels, but I only did E2 - I have to pay in full for whatever testing I do, and my pockets aren't deep. So if it's possible, I'd like to settle on a reasonable course of action to see if a lower E2 level might bring some improvement and make me a horny teenager again.
I have some 1/4 mg Arimidex tablets that I got several years ago from a Chinese gentleman named Josh, but never used. I though I would begin taking that, and then test E2 again. But take how much, and for how long?
How about - 1/16 mg dose, taken every other day, which would be roughly 1/4 mg per week. And then test again after maybe three weeks. But I have no idea how long it takes to reach a stable E2 state with Arimidex.
My plan would be to get E2 down to the low 20's, hoping that would get the job done. Does 1/4 mg per week sound like a conservative dose for someone not on TRT, at least a dose not likely to take E2 too low?
Any comments would be appreciated.