Topical selegiline and lethargy

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    Topical selegiline and lethargy


    Topical selegiline seems to make me very tired soon after I apply it and I use less than 1mg.

    Any ideas why this could be?

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    Quote Originally Posted by andrew david View Post
    Topical selegiline seems to make me very tired soon after I apply it and I use less than 1mg.

    Any ideas why this could be?
    Hard to say as it is a drug and everyone does respond differently. Have you tried oral?

    Oral selegiline makes me a little more wired due to the conversion of amphetamines and I would think it would have the same effect on you. However I already know that I am somewhat deficient in epinephrine and nor-epinephrine so I think it boosts that for me somewhat.

    I have read that Dr. Daniel Amen, whom is an expert on ADHD and ADD says if a patient's response is being tired while trying a drug like Adderall, it is telling him that the patient is taking too much of it. Now the opposite can be true to the non ADD/ADHD person in that they will experience a high.
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    Quote Originally Posted by Mr. V View Post
    Hard to say as it is a drug and everyone does respond differently. Have you tried oral?

    Oral selegiline makes me a little more wired due to the conversion of amphetamines and I would think it would have the same effect on you. However I already know that I am somewhat deficient in epinephrine and nor-epinephrine so I think it boosts that for me somewhat.

    I have read that Dr. Daniel Amen, whom is an expert on ADHD and ADD says if a patient's response is being tired while trying a drug like Adderall, it is telling him that the patient is taking too much of it. Now the opposite can be true to the non ADD/ADHD person in that they will experience a high.
    I have not tried oral selegiline.

    However, I do take 10mg or so of oral ritalin for ADD and it works great with no tiredness. I have also tried topical ritalin and that makes me tired.

    Perhaps I should try oral selegiline or modafinil. I suspect that this could replace my need for ritalin.
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