Could TRT actually lower the pregenolone and dhea levels possbile due to the activation of the p450 cytochrome enzyme.
Im not sure by which enzyme it acts upon or specific mechanisms involved, but yes I have read the same thing.Could TRT actually lower the pregenolone and dhea levels possbile due to the activation of the p450 cytochrome enzyme.
Im not sure by which enzyme it acts upon or specific mechanisms involved, but yes I have read the same thing.
Many cutting edge Dr's are aware of this and backload preg cream + Dhea supplements. Dhea is poorly absorbed orally, so it would make better sense to just add it into the preg cream as a combo.
If one had a decent T level to begin with, they could easily make due with DHEA + Preg Cream as a TRT mechanism.
One more test to see how it works before I go Dr route :nutkick:Hence creation for the that Stuff you are taking HAHA i thought you seeing DR J he will not like you are one that it will skew the test :nono:
go as natual as you can right !!One more test to see how it works before I go Dr route :nutkick:
Trying to. If I end up the Dr route, after all my bad behavior though Dr J just might give me one of these :nutkick:go as natual as you can right !!
Give you A: for effort :thumbsup:Trying to. If I end up the Dr route, after all my bad behavior though Dr J just might give me one of these :nutkick:
You will probably have issues with oral DHEA as alot do.My DHEA has fallen quite a bit since going back on 'real' TRT (vs Nolvadex every day). I have a bunch of oral DHEA, but I'm going to see if I can get my doc to prescribe Pregnenolone cream.
Have you guys who have been on TRT for awhile and then added preg/DHEA back in later noticed anything? Low DHEA is bad for adrenal fatigue.
Sonny
Full steam 1000 MPH ahead is the only speed I know :thumbsup:Give you A: for effort :thumbsup:
It seems like 3 out of 4 or so people are okay with oral DHEA. Thats still alot not absorbing well.I was told by my Dr that oral pregnenolone is very simple substance, like cholesterol & is abosorbed with no problems orally. I've got low pregnenolone and low DHEA, and have begun supplementing with both orally.
I don't have after blood tests for pregnenolone, but DHEA definately increased by taking orally
before blood test
DHEA-s 3.18 (Range 3.3-14.10umol/L)
after 75mg oral DHEA
DHEA-s 8.68 (Range 3.3-14.10umol/L)
I have since upped to 100mg DHEA per day (split 50morning, 50 night), will see how my next blood test results are.
DHEA will keep cortisol in check. DHEA goes up - high cortisol goes down.and AM cortisol also dropped. I am holding out for another DHEA blood test before I do anything. Gotta love how we can use ourselves as science experiments.
Sonny
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