testosterone/estrogen ratio

[phatkid77]

i searched, but obviously not well....what is my ratio and what do we require....50:1?

my last test was

testosterone... 397....hass been 335-365
estrogen ........78...converts to 21

im guessing 20:1

enjoy

[KSman]

i searched, but obviously not well....what is my ratio and what do we require....50:1?

my last test was

testosterone... 397....hass been 335-365
estrogen ........78...converts to 21

im guessing 20:1

enjoy

Some would state free T to free E, FT:FE. I have not see a definitive statement, but the ratio does have an effect. And a ratio also needs to be in the context of absolute levels as well. For me, the idea of T:E is a concept to explain how changes to E levels have an effect. Good examples are guys with high TT, high FE and high DHT who have brain fog, problems with mood, energy, ED, sexual performance; who then have all of that fixed when E is lowered with an AI. In this case, the inputs and levels of T are known and fixed and only the E is changed. That is an example of a change in T:E and E while T is not changed. I have seen a few statements that E2=17-20 is optimal from a libido point of view. So that seems to be a target that one could aim for while there are no stated targets for T:E. And as we find T levels all over the map with TRT, a T:E ratio might be better as a concept than a target number.

[JanSz]

Some would state free T to free E, FT:FE. I have not see a definitive statement, but the ratio does have an effect. And a ratio also needs to be in the context of absolute levels as well. For me, the idea of T:E is a concept to explain how changes to E levels have an effect. Good examples are guys with high TT, high FE and high DHT who have brain fog, problems with mood, energy, ED, sexual performance; who then have all of that fixed when E is lowered with an AI. In this case, the inputs and levels of T are known and fixed and only the E is changed. That is an example of a change in T:E and E while T is not changed. I have seen a few statements that E2=17-20 is optimal from a libido point of view. So that seems to be a target that one could aim for while there are no stated targets for T:E. And as we find T levels all over the map with TRT, a T:E ratio might be better as a concept than a target number.

Not long ago we were talking about TotalTestosterone rather exclusivey. Now most realize that the actual value is in Bioavailable and as second in importance, Free Testosterone.
Total Testosterone is just good starting conversation maker.

I think same apply to Estrodial and Total Estrogens.
so:
Start conversation with
Estrodial, serum, Ultrasensitive
but make sure you also test for
Estrodial, bioavailable
and
Estrodial, Free

add also

Estrodial, serum, fractionated
(contains E1, E2, E3)

and
Estrogen, Total, Serum

for the concisely written list of
======================
Estrogens, Total, Serum
Estradiol, Fractionated, serum
Estradiol, Bioavailable
Estradiol, Free
======================
and again, this can be had only at Quest Diagnostics.
======================

I am assuming that it will not be long when Quest will do combined test for Estrogens, similar to their
(Free BioAvailable and Total testosterone)

that test contain additionally information on Albumin and SHBG.

Since many values are interrelated, additional accuracy could be probably achieved when group of tests is done as a panel.

[wildfox]

KSMan explains it well. Remember the free testosterone and free estrogen compete at the same receptors. You want sufficiently excessive free T as compared to E so that testosterone wins most (but not all) of the time.