What are the symptoms of low dopamine?
Any thoughts or comments on one can differentiate? Sounds just like low T!Depression, low sex drive, lack of drive, lack of concentration
This, I believe is the reason that people feel crappy with lowT. Low T=Low Dopamine=high prolactin.Any thoughts or comments on one can differentiate? Sounds just like low T!
How to raise serotonin?Depression is more low serotonin, low dopamine is boredom, lack of interest and motivation, poor communication(particurly verbal), lack of confidence.
low T causes low DA. Could be one in the same issue. Higher T should increase DA.Any thoughts or comments on one can differentiate? Sounds just like low T!
Oxitriptan, hmmm. Is it a script? If so, for what exactly. I've never heard of it. Sounds worth trying.How to raise serotonin?
Oxitriptan - WorldHealth.net
Oxitriptan
Posted in Hormones & Pharmacological Agents on Wed March 19, 2008
GENERAL DESCRIPTION:
Oxitriptan or 5-hydroxy-tryptophan (5HT) is converted into the neurotransmitter serotonin in the body. Serotonin is a key factor in mood regulation, and the reduction of depression and anxiety. A lack of serotonin has been linked to compulsive disorders, especially the overeating of carbohydrates. Serotonin is also the precursor to the pineal gland’s production of melatonin. As serotonin levels decline with age, supplementation with the amino acid L-tryptophan (the body produces serotonin by converting L-tryptophan to 5 hydroxy-tryptophan via a vitamin B3 dependent enzyme, and then converting 5HT to serotonin via a vitamin B6 dependent enzyme), or the drug Oxitriptan is beneficial. Oxitriptan’s advantage is that, unlike L-tryptophan, it is used solely by the brain for the manufacture of serotonin, and is thus more effective in increasing serotonin levels.
ROLE FOR ANTI-AGING:
Oxitriptan’s anti-aging benefits may include the prevention and treatment of depression, maintenance of serotonin levels as the body ages, prevention and treatment of compulsive disorders like overeating, improved daytime alertness and treatment of insomnia.
I did try it too, did not feel difference.Oxitriptan, hmmm. Is it a script? If so, for what exactly. I've never heard of it. Sounds worth trying.
Ah, I now see it's just 5HTP. Never did much for me. I take 100 mgs at night.
have you tested this before and after?I'm on an amino acid program to balance neurotransmitters. Amino acids can cross the blood-brain barrier and raise neurotransmitter levels in the central nervous system. L-tyrosine is the amino acid that raises dopamine. So does mucuna pruriens. You have to have a 'tyrosine base' before adding mucuna. Try working up to 1 - 1.5 grams of tyrosine 3 times per day on an empty stomach. Then add 300 mg mucuna to each of the 3 tyrosine doses.
Never heard this before. Are you certain? I though tyrosine increased NA. I know there is a nexus between NA and DA, so you may well be correct. I've just never heard it before. I cant afford to increase NA any more, as I am already elevated.I'm on an amino acid program to balance neurotransmitters. Amino acids can cross the blood-brain barrier and raise neurotransmitter levels in the central nervous system. L-tyrosine is the amino acid that raises dopamine. So does mucuna pruriens. You have to have a 'tyrosine base' before adding mucuna. Try working up to 1 - 1.5 grams of tyrosine 3 times per day on an empty stomach. Then add 300 mg mucuna to each of the 3 tyrosine doses.
L-DOPA (3,4-dihydroxy-L-phenylalanine) is a naturally occurring amino acid found in the human brain and in certain plants (Macuna pruriens aka velvet bean). L-Dopa is produced from the amino acid L-Tyrosine via the enzyme tyrosine 3-monooxygenase (previously called tyrosine hydroxylase). Afterwards L-Dopa is able to cross the blood-brain-barrier and converts into Dopamine by the Vitamin B-6 dependant enzyme aromatic-L-amino-acid decarboxylase.
Conversion to dopamine also occurs in the peripheral tissues, i.e. outside the brain. This is the primary mechanism of the adverse effects of levodopa. It is standard clinical practice to co-administer a peripheral DOPA decarboxylase inhibitor—carbidopaCarbidopa
Carbidopa is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism of levodopa....
or benserazideBenserazide
Benserazide is an inhibitor of DOPA decarboxylase that does not enter the central nervous system....
—and often a catechol-O-methyl transferaseCatechol-O-methyl transferase
Catechol-O-methyl transferase is an enzyme first discovered by biochemist Julius Axelrod....
(COMT) inhibitor, to prevent synthesis of dopamine in peripheral tissue. Co-administration of pyridoxine without a decarboxylase inhibitor accelerates the extracerebral decarboxylation to such an extent that it cancels out the effects of levodopa administration, a circumstance which historically caused great confusion.
Wow, it would explain a lot of my problems. I have high prolactin and this causes a low dopamine. I've been having brainzaps (like little electric shocks in the head) for almost two years and I feel them often thru the body till my left feet... The same symptoms are usual after using Antidepressants... I've never used antidepressantsSomething else to keep in mind:
Gutter, is L-Dopa pretty similar to Levodopa? And does it play nicely with Deprenyl? It seems I recall suggestions to combine the two. Do you take it before bed, and does it help getting to sleep and/or promoting restful sleep?I've spoken to a Dr on another board, and he told me to stay away from l-tyrosine and stick only to l-dopa (because of adrenals).
fwiw, I have been using Unique Nutrition's L-dopa (not mucuna puriens). It's not stimulating, it tends to make me a bit sleepy.
Gutter, is L-Dopa pretty similar to Levodopa? And does it play nicely with Deprenyl? It seems I recall suggestions to combine the two. Do you take it before bed, and does it help getting to sleep and/or promoting restful sleep?
TIA.
define low or high dose on deprenyl. I see dosages ranging seriously from 2.5mg/week to 10mg a day. i'd say no more than 1mg a day, or since its a suicider could try 2.5mg 2x a week. With caber, similarly i'd say no more than 250mcg 2x a week. and be REALLY careful taking l-dopa at that point, definitely titrate your way up.Not with l-dopa/mucuna...doesn't do much for me besides make me tired. But caber I believe is having a decent effect on motivation. I am curious of throwing in some low dosed l-deprenyl with the low dosed caber and cycle both.
I take 2.5 mgs per day, sublingually -- pour capsule contents in mouth. 5 mgs per day interrupted sleep. I also take SAMe and Rhodiola, and find they help dopamine as well.define low or high dose on deprenyl. I see dosages ranging seriously from 2.5mg/week to 10mg a day. i'd say no more than 1mg a day, or since its a suicider could try 2.5mg 2x a week. With caber, similarly i'd say no more than 250mcg 2x a week. and be REALLY careful taking l-dopa at that point, definitely titrate your way up.
Keep in mind what each does - the deprenyl slows the removal of dopamine from system by inhibiting the enzyme that converts it, and caber will upregulate receptors. so you have more in bloodstream longer and are more sensitive
I have seen people recommend 500mcg of caber 2x per week. I have been trying this. Maybe I will lower my dose.
FWIW,define low or high dose on deprenyl. I see dosages ranging seriously from 2.5mg/week to 10mg a day. i'd say no more than 1mg a day, or since its a suicider could try 2.5mg 2x a week.
I feel like this often as well. L-dopa and deprenyl didn't do anything for me personally. Stablon on the other hand works wonders, but I had to take higher than the recommended dose. It is underdosed.For me at times i feel almost complete anhedonia (inability to feel pleasure). And inability to feel love and sense attachment to another person.
I feel like this often as well. L-dopa and deprenyl didn't do anything for me personally. Stablon on the other hand works wonders, but I had to take higher than the recommended dose. It is underdosed.
Its a supplement. Do some research.
I'm reading more into it now. But as you say i don't think it will help, i don't think so either.I just mean do an L-dopa search on here and do some thread reading. For some it helped in some aspects, and for other it has made them feel worse. I thought about L-dopa, but after some research, I don't think it will help.