Supplementation with testosterone (over time) will cause testicles to shrink. As they shrink, gradually native T production diminish.
If one uses HCG, that keeps testicles in their full size and therefore native T production is keept.
From reports of otheres, I see that the amount of testicle shrinkage depends on individual. In my case they were gone to almost nothing.
There is always confusion (probably by design) about DIM and I3C. It is hard to get straight answer.
Dr John recomends 300mg/day, but description of manufacturer (important) is missing.
Also if you study this subject a little, question arrises, the 300mg is it all bioavailable or actually the dose is 75mg of bioavailable DIM. 0.25*300=75mg
Important distinction, since diffrent manufacturers use either to describe content of their product.
MESO-Rx - View Single Post - I am on HRT with DIM...
read also the whole thread, lots of good info (and confusion) on DIM & I3C.
As always,
1. do the blood test
2. implement your new routine for at least a month, better two months
3. do a blood test, see what works what not, make adjustments