I have been on testosterone TRT for 5 months. I was diagnosed with hypogonadism. I also have hypothyroidism and I take .100 of Synthroid every day. I inject .4 ml of testosterone cypionate every 4 days. Before I started TRT my testosterone it was around 200. I felt tired, no libido, bad erections. The symptoms have improved slightly but I am worried about estrogen, triglycerides and HDL numbers. I am 40 years old, and I am 6’0 ,and weigh 190. I lift weights three times a week and I run 30+ miles per week. I eat well and I am very active. My doctor agreed my estrogen is too high, but he is worried that taking an estrogen blocker will further lower my HDL, so he recommended that I take 2000mg of niacin a day to see if my HDL goes up and triglycerides come down to within range. Then he will give me something to lower estrogen. Since on TRT I feel like I have gained weight in mid-section, libido and erections are only a little better. I have also gained about 20 pounds. And I have noticed I have less endurance running, I used to run 7 minutes per mile in a half marathon, now I am lucky to run under 9 minutes per mile. All of my training has been the same. Will taking an estrogen blocker fix my symptoms? Will niacin help with cholesterol numbers? Any advice is greatly appreciated.
Here are my latest numbers, from Quest Diagnostics.
Total testosterone 950...... 250-1100 ng/dl
Free testosterone 294........ 35 – 155 pg/ml
Estrogen , Serum 182 ........130 or less pg/ml
Cholesterol total 151........ <200 mg/dl
HDL Cholesterol 27 .........>40 mg/dl
LDL Cholesterol 86 .........<130 mg/dl
Triglycerides 191 .........>150 mg/dl