Labs Test to see if Human Growth Hormone is real

[Mako100]

I want to get lab work to see if this stuff is real..........do I need to get a baseline first or can I just run some to see if my levels go up above normal range....

 

[The Matrix]

I want to get lab work to see if this stuff is real..........do I need to get a baseline first or can I just run some to see if my levels go up above normal range....

Measure it via urine its 199.95 from private labs md or serum IGF-1 be cheaper..

 

[Mako100]

Measure it via urine its 199.95 from private labs md or serum IGF-1 be cheaper..

I'm getting, IGF-1, Growth Hormone Serum, TSH, Test, Thyroxine, Gluclose

It's 3 test. HGH, Test, and Acromegaly....around $150 with discount code

 

[Mako100]

Will Melanotan II effect HGH levels.....I want to start running MII but don't want to with the possibility that the lab results will be wrong,.....thanks!

 

[Mako100]

Does anyone know about running Melanotan II and the effect it may or not have on a HGH test?

 

[rambofireball]

You going to be posting your bloods results? I'd be interested.

 

[Mako100]

This is the base line report

 

[rambofireball]

Legit with the scan!

What are you going to run? And how long?

I have no idea about the melanotan, sorry dude, you gonna hold off?

 

[Mako100]

Legit with the scan!

What are you going to run? And how long?

I have no idea about the melanotan, sorry dude, you gonna hold off?

Yea I'm run the HGH monday and get labs done

 

[Mako100]

Here we go.......bunk BS

fasted 12, ran 10 iu's and waited 3 and the labs don't lie..........labs we about $300 + the bunk HGH :irked:

 

[rambofireball]

Maybe you should run it longer, to see if there is an additive effect? When I was prescribed GH by my endo, we waited a month to test my IGF-1, I guess the blood level builds over time. I'm not very familiar with RC GH/GF's, but I was prescribed GH a while ago and it ran me something like $1000 a month, needless to say I stopped when I found out the insurance wouldn't cover it... But if your getting this GH for anything much cheaper, I'd think that would also be reason for doubt.

 

[EasyEJL]

why did you wait 3 hours after? I'm not sure how long the gh stays in system, or the igf after either.

 

[rambofireball]

GH has a really short half life. It's pretty standard practice to not even test GH levels directly but to instead test IGF-1.

http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.1989.tb00444.x/abstract

The half-life determined in the above study is between 7.6-10.4 minutes. Apparently the previously determined half-life was 10-15 minutes, but the researchers argue this study provides a more accurate half-life.

So, that, coupled with the fact that it takes an extended period of use in order for blood IGF-1 to rise, makes me think you should run whatever supply you have and get another test towards the end -preferably less than 10 minutes after a dose. Although, chances are that the GH in the sample may not survive the trip to the lab, reconstituted GH lasts usually 3 weeks if refrigerated, reconstituted GH in blood at body temperature.. not so much. I'd stick with the IGF-1 test. It's much cheaper too.

Did you read up on proper reconstitution technique? It's pretty specific, and if done improperly will yield a really low amount of GH.

 

[The Matrix]

Here we go.......bunk BS

fasted 12, ran 10 iu's and waited 3 and the labs don't lie..........labs we about $300 + the bunk HGH :irked:

<img src="http://anabolicminds.com/forum/attachment.php?attachmentid=60869"/>

<img src="http://anabolicminds.com/forum/attachment.php?attachmentid=60870"/>

Probably hcg ...

 

[Mako100]

Peak plasma concentrations are about 2-4 hours after administration.....or so I read

 

[The Matrix]

Peak plasma concentrations are about 2-4 hours after administration.....or so I read

Friend was on 4 ius of humatrope for 3 months. 2 weeks after stopping it IGF-1 levels where at 419 ..Tells you right there what you should see especially taking amount you where taking. 10 ius should have pushed into the 600-700 range.

 

[Mako100]

Friend was on 4 ius of humatrope for 3 months. 2 weeks after stopping it IGF-1 levels where at 419 ..Tells you right there what you should see especially taking amount you where taking. 10 ius should have pushed into the 600-700 range.

Yea.......nice huh.....maybe I can sprinkle in on my corn flakes :toofunny:

 

[rambofireball]

Peak plasma concentrations are about 2-4 hours after administration.....or so I read

Where did you get that info?

I was told by my endo that it was in and out ~20 mins. This is what I have been able to find in addition to that:

Demonstrating Half-life of GH
http://www.ncbi.nlm.nih.gov/pubmed/1464653
"No difference was noted in the half-life of GH between the two groups (13.8 +/- 0.9 vs. 14.2 +/- 0.4 min)."

http://www.deadiversion.usdoj.gov/drugs_concern/hgh.pdf
"The circulating half-life of hGH is relatively short half-life (20-30 minutes), while its biological half-life is much longer (9-17 hours) due to its indirect effects."

The study I posted before
http://onlinelibrary.wiley.com/doi/1...444.x/abstract
The half-life determined in the above study is between 7.6-10.4 minutes.

Friend was on 4 ius of humatrope for 3 months. 2 weeks after stopping it IGF-1 levels where at 419 ..Tells you right there what you should see especially taking amount you where taking. 10 ius should have pushed into the 600-700 range.

I'd agree if mako100 had been taking the GH for 3 months, or any extended amount of time, but the guy took one dose. Everything I've read and the convos I've had with my endo have led me to believe that IGF-1 levels will build over extended periods of administration, meaning that a low IGF-1 would be expected in the second blood lab mako100 had drawn.

Please show me some evidence if I'm wrong as I don't want to be spreading wrong info, and would like to have the facts straight for myself. Much thanks.

 

[EasyEJL]

maybe he's right

Table 1: Summary of somatropin pharmacokinetic parameters in the normal population following a 4 mg dose of Accretropin™ (somatropin injection) administered subcutaneously*

	AUC[SUB](0-t)[/SUB] (ng•h/mL)	AUC[SUB](0-inf)[/SUB] (ng•h/mL)	Cmax (ng/mL)	Tmax (h)	t[SUB]1/2[/SUB] (h)
mean ± SD	238.09 ± 44.11	255.31 ± 43.03	29.49 ± 8.32	3.50 (2-6)	3.63 ± 1.33
*Abbreviations: AUC[SUB]0-t[/SUB]=area under the curve until 24 hours after administration; AUC[SUB]0-inf[/SUB]=area under the curve to infinity; Cmax=maximum concentration; t[SUB]½[/SUB]=half-life; Tmax=time to maximum concentration (given as the median value with range); SD=standard deviation.

4mg would be 12iu. but obviously given ranges, these #s can't be hgh amounts, so i'm guessing they are igf-1 levels, which seems like it matches your report

 

[rambofireball]

maybe he's right



4mg would be 12iu. but obviously given ranges, these #s can't be hgh amounts, so i'm guessing they are igf-1 levels, which seems like it matches your report

I'm taking AUC(0-t) to be the mean blood level of IGF-1, 3.5 hours after the single dose of GH @ 12iu. Is this correct? If that is the case, then I'd say the 10 ng/mL increase from test 1 to test 2, although pretty insignificant, may lend toward the GH being legit?

Could you post the entire study? I feel like I'd have an easier time understanding exactly what this table is saying.

 

[EasyEJL]

I'm taking AUC(0-t) to be the mean blood level of IGF-1, 3.5 hours after the single dose of GH @ 12iu. Is this correct? If that is the case, then I'd say the 10 ng/mL increase from test 1 to test 2, although pretty insignificant, may lend toward the GH being legit?

Could you post the entire study? I feel like I'd have an easier time understanding exactly what this table is saying.

that was from the pharmacy labeling for Accretropin

 

[rambofireball]

Ok, I found the pharmacy labeling, and this was also there.

Figure 1. Mean serum hGH levels over time following single dose administration.


So.... I'm really confused lol. There's all those studies saying the half-life is at most a half hour, and this company saying you peak just before 4 hours, and you've still got 5 ng/mL after 18 hours... ftw.​

 

[EasyEJL]

Ok, I found the pharmacy labeling, and this was also there.

Figure 1. Mean serum hGH levels over time following single dose administration.


So.... I'm really confused lol. There's all those studies saying the half-life is at most a half hour, and this company saying you peak just before 4 hours, and you've still got 5 ng/mL after 18 hours... ftw.​

well, if that is at a 12iu dose, it maybe makes sense as i've never seen it prescribed significantly above 1iu. Then at least it makes more sense vs human range as per the blood test. Confusing though as to why they'd dose it so crazily high for the pharmokinetics tests

 

[rambofireball]

well, if that is at a 12iu dose, it maybe makes sense as i've never seen it prescribed significantly above 1iu. Then at least it makes more sense vs human range as per the blood test. Confusing though as to why they'd dose it so crazily high for the pharmokinetics tests

Lol, yeah, that does make sense. And I guess that kinda answers the whole question of mako's GH being legit, if he pinned 10iu's and had his blood drawn 3 hours after, it probably should have been in the 20's I guess.

Well, I learned a lot today. Thanks for helping out EasyE.

 

[BigChrisG]

Yes the tests prove the HGH was bunk.. You can get real Pharma grade HGH for around 5 bucks an IU so less than the 1000 bucks a month but none of the chinese crap is going to be legit. might test high on hg serum but the IGF-1 tests will be low they mix mostly bio inactive hgh with a little correctly produced hgh which kicks your gh serum levels up but does nothing for igf-1 which is the test that matter and proves the chinese stuff is bunk

 

[rambofireball]

Yes the tests prove the HGH was bunk.. You can get real Pharma grade HGH for around 5 bucks an IU so less than the 1000 bucks a month but none of the chinese crap is going to be legit. might test high on hg serum but the IGF-1 tests will be low they mix mostly bio inactive hgh with a little correctly produced hgh which kicks your gh serum levels up but does nothing for igf-1 which is the test that matter and proves the chinese stuff is bunk

Very interesting, mind if I ask how you came about that information?