I'm looking for an explaination, as to why, T4 (Synthroid) would exacerbate an Under Methylation (UM) problem?
I had no hint of any histamine problems until I was put on T4. T4 increased my UM, and made me unable to tolerate most high content polyphenols.
P5P, Metafolin, Methyl B12, Choline, has stopped 10 years of inexplicable rhinitis, started by T4.
Matrix, do you have any insight in to why T4 would stress my methyl reserves?
It is dosage related; the more T4, the worst the allergic reaction.
T3 did not add to my UM, only T4.