I'm looking for an explaination, as to why, T4 (Synthroid) would exacerbate an Under Methylation (UM) problem?
I had no hint of any histamine problems until I was put on T4. T4 increased my UM, and made me unable to tolerate most high content polyphenols.
P5P, Metafolin, Methyl B12, Choline, has stopped 10 years of inexplicable rhinitis, started by T4.
Matrix, do you have any insight in to why T4 would stress my methyl reserves?
It is dosage related; the more T4, the worst the allergic reaction.
T3 did not add to my UM, only T4.
I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.