Has anyone been on trt for 10 or more years

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    Has anyone been on trt for 10 or more years


    im concern with being prescribing testosterone replacement therapy is to be ineffective in the long-term treatment of aging. have you had to keep uping the dose?

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    Been "on" since 2007. Switched from gels to IM injections two years ago. Haven't had any issues. But, one time my doctor had me go "off" for a month to get a new baseline and my total T was 190. I felt like complete crap and hated the world. Never again will I go "off" test.
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    If you stay in a healthy range, you shouldn't need to up the dose. That only occurs if you're constantly overloading your androgen receptors (ie: going over the range). This overtime, will downregulate the AR.

    You can always look into l-carnitine-l-tartarate (LCLT) to help prevent this.

    I occassional go 'off' by going onto HCG monotherapy. Once a year or so I've done this since starting. I wouldn't recommend it though honestly, unless you are really in tune with your body.
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