I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
I too am going through a Clomid restart. I was on 25mg day but felt crappy. I'm now on 12.5mg day, still feel a little tired but much better. I'm thinking of going to the 25mg every four day schedule.
Are you still on 25mg E4D? Also, do you take it in the morning when you wake or at bedtime?
Hope your doing well.
I don't really have a set schedule. I usually just take it as soon as I remember about it that day..