Best dosing schedule for test cyp.

Bigdaddy46

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I have been on TRT for the past year. My dr. has me doing 150 mg. test cyp every two weeks. But I felt that by the end of the two weeks I was starting all over again. So I started doing 75 mg. every 7 days, but from what I have seen on here maybe I should be dosing sooner? I thought about 50 mg. every 5 days instead of 75 mg. every 7 days. Will it really make that much difference? I know 300 mg. a month doesn't seem that high but it has raised my levels from 270 to 575 and I am happy with that. More doesn't necessarily equate to better. Thanks for any ideas.
 

pmgamer18

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OK doing shots every 2 weeks is very old it's on the insert that comes with Depo T, Test C and Test E but it's old. Doing big shots every 2 weeks puts you on a Roller Coaster Ride up after the shot only to fall to low by the next one. We don't feel bad going up on the level but we do feel it bad going down to low.

Even in the AACE Guildelines it states on page 11 to do shots every 7 to 10 days and this is very old. Most men do shots once a week starting at 100 mgs yet others find it works better doing them at 50 mgs 2x's / week.

I do my shots every 3 days I find out about this when I read Dr. Shippen he did the book "The Testosterone Syndrome" he dose his shots on his self every 3 days and subQ spliting up the shot into 2 shots each time one on one side of his belly the other on the other side. He found this helps keep him more leveled and helps keep his Estradiol levels down. If you don't test Estradiol and it's high it will undo any good the TRT your on is doing.

Also doing shots more offten helps keep your blood thinner.
https://www.aace.com/sites/default/files/hypogonadism.pdf

Show this to your Dr. and talk to him about his my Dr. will not let me do shots subQ so he told me use a small 27g 1ml x 1/2" lg. needle and shoot into my thigh. The oil comes out slow so I just pull the plunger all the way down and hold it until I get my dose takes about a min.
 
MidwestBeast

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I would think that once a week at that dose wouldn't be that bad; especially since it's a forever thing and shooting "every 4th" day can get annoying as it would fall on different days of the week. Obviously those with more experience in TRT can offer better advice, but I like the idea of going 75mg/week.
 

oldguns

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My doctor just changed me to every third day with 50 mg using a 25g 5/8 needle into the delts.
 

pmgamer18

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To add to this I do 250 IU's of HCG the day before my next Test C shot every 3 days this helps to keep my testis working and ups my libido.
My doctor just changed me to every third day with 50 mg using a 25g 5/8 needle into the delts.
 

oldguns

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To add to this I do 250 IU's of HCG the day before my next Test C shot every 3 days this helps to keep my testis working and ups my libido.
I'm on test e and doc is setting my level at 700. But he not a big fan of hcg, last time we talked about it he gave me some samples and a script for cialis...LOL. Shortly I'm going to be adding the hcg on my own.
 
The Matrix

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. This what I am doing having constant e2 levels stable for 3 months then adding in 100 ius day before the shot then remeasure in 4 weeks to see the change then increase 50 ius every 3 weeks then retest till I find where e2 rises too high then back off to proper dosage. This is what is working for me
 

Bigdaddy46

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My Dr. never has checked my e2 levels. Also I am using 23g x 1 to inject into my delts, would I be better to use something smaller? I used to inject into my glutes but my Dr. told me not to for fear of hitting a nerve. What size pin would be best if I injected in the quad?
 
The Matrix

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My Dr. never has checked my e2 levels. Also I am using 23g x 1 to inject into my delts, would I be better to use something smaller? I used to inject into my glutes but my Dr. told me not to for fear of hitting a nerve. What size pin would be best if I injected in the quad?
Hittin a nerve with one inch. You have to be either blind or drunk for that to occur. I use 29 gauge 1/2 inch to shot and a bigger one to load the smaller syringe.
 

pmgamer18

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Like Matrix I use a smaller size needle 27g 1ml. x 1/2" lg. and I shoot into my thigh I do my shots every 3 days for Test C and I shoot HCG the day before been doing this for yrs.
My Dr. never has checked my e2 levels. Also I am using 23g x 1 to inject into my delts, would I be better to use something smaller? I used to inject into my glutes but my Dr. told me not to for fear of hitting a nerve. What size pin would be best if I injected in the quad?
 
The Matrix

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If hcg is going to cause issue with unstable.e2 levels all.over the place resulting emotional.ed issues bloating etcetera I will take small.balls any day and better quality of life. The little bastards can still pump out a load of goo on any given day. Small balls.does not.make.you less of a men. Dealing with e2 issues crying at drop of a.dime and being bloated will.
 

pmgamer18

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Do you mean your Testicles are removed is so taking HCG will not do a lot for you like Matrix says if you try it and it makes you feel bad it's not worth it. I use HCG it keeps my Testis working as for Estradiol I have high levels on or off HCG and I feel better on HCG here is a cut and paste Dr. John sent me to help me get my Dr. to let me try HCG. When I went on it doing 500 IU's 3x's / week my Total T levels went from 600 to 1200 and I took this with my Depo T shots 150 mgs / week.
Doing this is how we figured out I am not Primary but I am Secondary it's called Hypopituitary.
=========================================================================
He probably feels that since you suffer primary hypogonadism (I am guessing) there is no use in adding HCG to your protocol. There are several reasons why this is not so. First, you have not lost all Leydig cells, so any HCG you take will stimulate those who still function to produce endogenous testosterone.

This will support testicular size. We should not ignore this aesthetic consideration.

Next, if he reads my work, he will learn that HPTA-suppressed (as all TRT patients are to some extent) also suffer decreased pregenenolone levels, which is the first step after CHOL in all three hormonal pathways which begin with CHOL. HCG increases pregnenolone production, and therefore restores a more natural balance of our hormones.

Next, nearly all TRT patients who add in HCG to their regimens report an increased sense of well-being and also libido. These are genuine quality of life issues.

Finally, I just instinctively do not want all those LH receptors (including those we have yet to discover and appreciate) unstimulated.


Is HCG relevant if testicles are gone?
 
The Matrix

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Do you mean your Testicles are removed is so taking HCG will not do a lot for you like Matrix says if you try it and it makes you feel bad it's not worth it. I use HCG it keeps my Testis working as for Estradiol I have high levels on or off HCG and I feel better on HCG here is a cut and paste Dr. John sent me to help me get my Dr. to let me try HCG. When I went on it doing 500 IU's 3x's / week my Total T levels went from 600 to 1200 and I took this with my Depo T shots 150 mgs / week.
Doing this is how we figured out I am not Primary but I am Secondary it's called Hypopituitary.
=========================================================================
He probably feels that since you suffer primary hypogonadism (I am guessing) there is no use in adding HCG to your protocol. There are several reasons why this is not so. First, you have not lost all Leydig cells, so any HCG you take will stimulate those who still function to produce endogenous testosterone.

This will support testicular size. We should not ignore this aesthetic consideration.

Next, if he reads my work, he will learn that HPTA-suppressed (as all TRT patients are to some extent) also suffer decreased pregenenolone levels, which is the first step after CHOL in all three hormonal pathways which begin with CHOL. HCG increases pregnenolone production, and therefore restores a more natural balance of our hormones.

Next, nearly all TRT patients who add in HCG to their regimens report an increased sense of well-being and also libido. These are genuine quality of life issues.

Finally, I just instinctively do not want all those LH receptors (including those we have yet to discover and appreciate) unstimulated.
Very good points as always phil
The thing I am wondering is just how much HCG is needed to stimulate the LH receptors to keep them functional through out the body? is 250 ius really the right dosage or is it even possible 100 ius 2 times a week? When on HRT I am not concerned with using HCG to boost test, but to find the right amount to keep LH receptors functional.
 

pmgamer18

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Yes 100 IU's the day before your next Test C shot or on gels every 3 days is enough to keep your LH cells working in your testis, body and brain. Men that are trying to keep there T levels up until there next shot can do more if there testis work. I am secondary my testis work fine when I take HCG they make a lot of T so I use this to keep them working and to help keep my levels up. Still If I use more then my testis can handle it turns into Estraidol E2. Some HCG like Novarel is much stronger the what the ADC sells and one needs to keep this in mind Novarel a 100 IU's I feel is = to 300 IU's of ADC's HCG.
Very good points as always phil
The thing I am wondering is just how much HCG is needed to stimulate the LH receptors to keep them functional through out the body? is 250 ius really the right dosage or is it even possible 100 ius 2 times a week? When on HRT I am not concerned with using HCG to boost test, but to find the right amount to keep LH receptors functional.
 
The Matrix

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Did novarel finally get that corrected about extra dosage it was producing?
 

DragonRider

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I would think that once a week at that dose wouldn't be that bad; especially since it's a forever thing and shooting "every 4th" day can get annoying as it would fall on different days of the week.
Personally, I've never seen the reason to be that exact. These guys who are injecting every 3rd or 4th day would do just as well injecting every Sunday/Wednesday or Monday/Thursday.
 

DragonRider

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Is HCG relevant if testicles are gone?
Absolutely not and I believe there is a doctor on this board now who just started TRT and is trying to manage it without HCG or an AI.
 
The Matrix

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Absolutely not and I believe there is a doctor on this board now who just started TRT and is trying to manage it without HCG or an AI.
smart man..Send him over here where he could may be learn some new information..As a health professional I am learning something new every day..
 

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The Matrix

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Forget the size of balls! HCG is very important for quality of life feeling if nothing else. E2 levels have to be kept in check absolutley. As far as Test shot frequency, an easy way to do it twice a week is to do it every 3 1/2 days. I do it Sunday morning and Wednesday evening. This gives equal time between each shot instead of doing every 3 days, making you have to consciously remember when your last one was.
 
The Matrix

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Every one system is different ,one can not make such a general statement.
 

j2048b

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alrighty so what evryone here is saying, example:

i am going to be taking test cyp at 1ml= 100mg e5d, and i was told to take my hcg the day after, not before,

and also take my anastrozole (might switch to aromasin, as it seems to bind better from what ive read and been told by others?) the day after with my hcg, is this a bad thing?

also got on some cytomel, due to thyroid, pyrimad this for 6 weeks,

should i actually be taking 1/2 of my 1ml 2 times a week, and take my hcg WHEN?) along with my Ai?

any info greatly appreciated and helpfull in this matter!



thanks matrix and or pmgamer18, gutterpump, and dragon! you guys know your stuff!
 
The Matrix

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My HCG is taken the day before the injection. As pmgamer told me "think as it as kicking in the nitric oxide on a dragster" because it gives you that extra boost. Taking the day after the shot is a waste as well as creating a potential huge estrogen spike. You do not cycle t-3 its something you stay on for life as if you have a thyroid condition.

AI need to be taken according to half life.
When recommending HRT to dr's I always encourage them to run with out an AI for the first 5 weeks. The reason behind this is I have seen people with high e2 actually come down when testosterone levels are elevated into the upper 1/3 range. Many people are shooting them selves in the foot. Many of the Dr's patient complain of high e2 like symptoms and want to start demanding for an AI right away. Majority of the time this is not due to high e2 but the body getting used to higher testosterone levels since it has not been exposed to them for Lord knows how long. I have found this through my own experience and pmgamer brought it to my attention as well. In the past I had recommended dr's to have their patients level tested when this was occurring and it was found out it e2 was with in normal range (20-30 and in relationship to shbg).

After 5 weeks the dosage of AI depends on the amount of e2 levels. People on HRT get over anxious wanting to take more and in the end less is better with anything. It is all about proper balance and optimizing what is already present.

alrighty so what evryone here is saying, example:

i am going to be taking test cyp at 1ml= 100mg e5d, and i was told to take my hcg the day after, not before,

and also take my anastrozole (might switch to aromasin, as it seems to bind better from what ive read and been told by others?) the day after with my hcg, is this a bad thing?

also got on some cytomel, due to thyroid, pyrimad this for 6 weeks,

should i actually be taking 1/2 of my 1ml 2 times a week, and take my hcg WHEN?) along with my Ai?

any info greatly appreciated and helpfull in this matter!



thanks matrix and or pmgamer18, gutterpump, and dragon! you guys know your stuff!
 

j2048b

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HCG is taken the day before the injection. As pmgamer told me "think as it as kicking in the nitric oxide on a dragster" because it gives you that extra boost. Taking the day after the shot is a waste as well as creating a potential huge estrogen spike. You do not cycle t-3 its something you stay on for life as if you have a thyroid condition.

AI need to be taken according to half life.
When recommending HRT to dr's I always tell them do not run an AI for the first 5 weeks. The reason behind this is I have seen people with high e2 actually come down when testosterone levels are elevated into the upper 1/3 range. Many people are shooting them selves in the foot. Many of the Dr's patient complain of high e2 like symptoms and want to start demanding for an AI right away. Majority of the time this is not due to high e2 but the body getting used to higher testosterone levels since it has not been exposed to them for Lord knows how long. I have found this through my own experience and pmgamer brought it to my attention as well. In the past I had recommended dr's to have their patients level tested when this was occurring and it was found out it e2 was with in normal range (20-30 and in relationship to shbg).

After 5 weeks the dosage of AI depends on the amount of e2 levels. If over 50 start with 1/4 tab every 3 days then hold this for 4 weeks till plasma levels are reach then make adjustments. People on HRT get over anxious wanting to take more and in the end less is better with anything. It is all about proper balance and optimizing what is already present.
thanks matrix!

i also sent you a pm, as i have a question about what you state here :)
 
The Matrix

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thanks matrix!

i also sent you a pm, as i have a question about what you state here :)

There could be multiple factors causing these symptoms you are having out side HRT. Problem with some Doctors are they focus on one area and forget the rest. In another 5-10 years these drs will be a thing of the past as more and more medical professionals are learning integrative medicine. My methodology follows this integrative approach resulting in dealing with the source of the problem not just dealing with symptoms.
 

j2048b

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1. Your dr is not following proper hRT protocol as thyroid is not cycles
2. There could be multiple factors causing these symptoms you are having out side HRT. Problem with some Doctors are they focus on one area and forget the rest. In another 5-10 years these drs will be a thing of the past as more and more medical professionals are learning integrative medicine. My methodology follows this integrative approach resulting in dealing with the source of the problem not just dealing with symptoms.

um ok mn thanks for the input and advice!
 

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