Hormone Pathway

  1. Hormone Pathway

    Can an enzyme deficiency be cause of hypogonadism? Specifically a p450 enzyme deficiency. It is my understanding the the p450 enzyme converts cholesterol into pregnenolone then testosterone and others.

  2. Yep:


    Since this condition affects all hormones, looking at cortisol, dhea, progesterone, etc... can help confirm it. A DNA test may be needed for conclusive confirmation.

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