Low LH, FSH, Free Test and Test 32 Year Old Male

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    Low LH, FSH, Free Test and Test 32 Year Old Male


    I did my 1st blood test 7/15/2009. The reason I did this test was because I had zero sex drive, no energy, storing fat and just felt mentally very unclear. I was working out hard and have always ate very clean and was still holding the fat no matter what I did. So I did the test below.

    7/15/2009
    Test- 453 (241-827)
    Free Test (Direct) 9.8 (8.7-25.1)
    TSH- 1.350 (.450-4.5)
    DHEA- 267 (120-520)
    IGF-1- 146 (115-307)

    Then on 7/28/2009 we did more testing to see if we could determine why test and especially free test were low.

    7/28/2009
    LH- 1.5 (1.5-9.3)
    FSH- 2.4 (1.4-18.1)
    Estrodial- 31 (0-53)

    7/30/2009 Doctor decided to inject 200MG of depo Test and retest levels which we did on 8/04/09
    TSH .596 (.450-4.500) WOW, super odd not sure what happened here???
    T4- 1.31 (.61-1.76)
    TEST- 1467 (241-827)
    FREE TEST- 39.9 (8.7-25.1)

    During this time I felt great sex drive was finally back, great moods, very alert, memory was greatly improved and so on. My doctor did not know much about injecting test the 1467 test number scared him so he said no second injection.

    We tested on 8/13/2009 as he wanted to see what my levels were at now. During this time I felt about the same as I used to feel before the shot, like ****, i did feel a little worse I was a little more tired and got headaches.

    8/13/2009
    Test- 182
    Free Test- 4.1
    Prolactin- 4.7 (2.1-17.7)

    8/14/2009 I did some research about re-start protocols and talked my doctor into one of them
    I took HCG m,w,f 300mg injected for 3 weeks total
    Clomid 100mgs a day split 50mg morning and 50 mg afternoon 4 weeks
    Nolva 20 mg, 10 morning and 10 at night 4 weeks

    I felt better on this and for about 2 months after it but I have slowly started to feel like **** again. HCG took fat off me like no other, sorry for the side note.
    We retested on 9/30 about 2 weeks after the end of the restart.

    9/30/2009
    Test 579
    Free Test 14.1
    LH- 5.7

    I have started to feel like **** again, no sex drive what so ever, no morning wood, very moody, no zest for life, no energy, mentally unclear and so on. So we re-tested on 1/12/2009

    1/12/2009
    DHEA 691 (146-850)
    TEST 563
    FREE TEST 11.7
    LH 3.8

    I am not sure where to go from here. From the research I have done, this would point to secondary hypogonadism. My LH is starting to fall again, I wish we would have tested FSH. I have worked with many docs on this and no one seems to have a clue about male hormones. The endo I met with said she would not talk to me unless my total test was under 100 and my hair was falling out. One of the other docs I have worked with says we might need to look deeper into the thyroid??? I am tired of feeling like ****, do you have any suggestions???

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    Quote Originally Posted by Bryce720 View Post
    I did my 1st blood test 7/15/2009. The reason I did this test was because I had zero sex drive, no energy, storing fat and just felt mentally very unclear. I was working out hard and have always ate very clean and was still holding the fat no matter what I did. So I did the test below.

    7/15/2009
    Test- 453 (241-827)
    Free Test (Direct) 9.8 (8.7-25.1)
    TSH- 1.350 (.450-4.5)
    DHEA- 267 (120-520)
    IGF-1- 146 (115-307)

    Then on 7/28/2009 we did more testing to see if we could determine why test and especially free test were low.

    7/28/2009
    LH- 1.5 (1.5-9.3)
    FSH- 2.4 (1.4-18.1)
    Estrodial- 31 (0-53)

    7/30/2009 Doctor decided to inject 200MG of depo Test and retest levels which we did on 8/04/09
    TSH .596 (.450-4.500) WOW, super odd not sure what happened here???
    T4- 1.31 (.61-1.76)
    TEST- 1467 (241-827)
    FREE TEST- 39.9 (8.7-25.1)

    During this time I felt great sex drive was finally back, great moods, very alert, memory was greatly improved and so on. My doctor did not know much about injecting test the 1467 test number scared him so he said no second injection.

    We tested on 8/13/2009 as he wanted to see what my levels were at now. During this time I felt about the same as I used to feel before the shot, like ****, i did feel a little worse I was a little more tired and got headaches.

    8/13/2009
    Test- 182
    Free Test- 4.1
    Prolactin- 4.7 (2.1-17.7)

    8/14/2009 I did some research about re-start protocols and talked my doctor into one of them
    I took HCG m,w,f 300mg injected for 3 weeks total
    Clomid 100mgs a day split 50mg morning and 50 mg afternoon 4 weeks
    Nolva 20 mg, 10 morning and 10 at night 4 weeks

    I felt better on this and for about 2 months after it but I have slowly started to feel like **** again. HCG took fat off me like no other, sorry for the side note.
    We retested on 9/30 about 2 weeks after the end of the restart.

    9/30/2009
    Test 579
    Free Test 14.1
    LH- 5.7

    I have started to feel like **** again, no sex drive what so ever, no morning wood, very moody, no zest for life, no energy, mentally unclear and so on. So we re-tested on 1/12/2009

    1/12/2009
    DHEA 691 (146-850)
    TEST 563
    FREE TEST 11.7
    LH 3.8

    I am not sure where to go from here. From the research I have done, this would point to secondary hypogonadism. My LH is starting to fall again, I wish we would have tested FSH. I have worked with many docs on this and no one seems to have a clue about male hormones. The endo I met with said she would not talk to me unless my total test was under 100 and my hair was falling out. One of the other docs I have worked with says we might need to look deeper into the thyroid??? I am tired of feeling like ****, do you have any suggestions???
    I would look into thyroid and adrenals deeper as well as life style and sleep patterns, Current stress issues, emotional trama, nutritent imbalances, heavy metals, gut issue, ect ..That is how I handle these cases look for the root cause not just treat symptoms
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    I agree with you 100% that is why I am trying to figure this out before I just treat the symptoms. I have a fair amount of stress, started a new business, lost my grandmother last year, been re-ended 3 times in the last year, Oh and there is the issue of my whole family is fighting over a trust.

    Emotional Trama have had a very ruff child hood, I don't want to go into it here.

    I sleep o.k., I usually get into bed about 9:00 p.m. and get up about 5:30. I usually sleep most of the night, usually have to pee once or so.

    I am not sure how I would check for nutritional imbalances?? I eat very clean.

    Heavy Metals, have no idea how to look into this?

    Gut issues, could be I worked with a ND who was thinking the same thing. We have tweeked my diet and I now take digestive enzymes to help me digest fats, and proteins. I have felt better and think my food is digesting better. All of my stools used to float, now they sink about 1/2 of the time??

    How would I look into thyroid deeper and or adrenals?? How do the few thyriod tests I did look??
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    Quote Originally Posted by Bryce720 View Post
    I agree with you 100% that is why I am trying to figure this out before I just treat the symptoms. I have a fair amount of stress, started a new business, lost my grandmother last year, been re-ended 3 times in the last year, Oh and there is the issue of my whole family is fighting over a trust.

    Emotional Trama have had a very ruff child hood, I don't want to go into it here.

    I sleep o.k., I usually get into bed about 9:00 p.m. and get up about 5:30. I usually sleep most of the night, usually have to pee once or so.

    I am not sure how I would check for nutritional imbalances?? I eat very clean.

    Heavy Metals, have no idea how to look into this?

    Gut issues, could be I worked with a ND who was thinking the same thing. We have tweeked my diet and I now take digestive enzymes to help me digest fats, and proteins. I have felt better and think my food is digesting better. All of my stools used to float, now they sink about 1/2 of the time??

    How would I look into thyroid deeper and or adrenals?? How do the few thyriod tests I did look??
    I am studying to be an ND for crying out load and probably one of the best in the USA with hormones and finding the cause . I actually have ND's that I counsel for their health issues.
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    Congrats on the ND route, I think my ND has took more time and care then my MD and all the other doc's I have worked with thus far. I agree 100% with you on finding the root cause. I don't want to start HRT at 32 if I don't have to.

    For instance today I got back from my MD appointment we went over my latest blood work and he wrote me a script for "compound testosterone cream". He told me to try it for a month and we will re-test. I appreicate him trying, but I want to the root of the problem not just instant relief.

    In my post aboice I was being honest about everything, not a smart ass. Sorry if I offened you. Thanks so much for all you help thus far.

    Did you see anything on the thyroid test's I have done and how do you test adrenal's? Thanks so much
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    Quote Originally Posted by Bryce720 View Post
    Congrats on the ND route, I think my ND has took more time and care then my MD and all the other doc's I have worked with thus far. I agree 100% with you on finding the root cause. I don't want to start HRT at 32 if I don't have to.

    For instance today I got back from my MD appointment we went over my latest blood work and he wrote me a script for "compound testosterone cream". He told me to try it for a month and we will re-test. I appreicate him trying, but I want to the root of the problem not just instant relief.

    In my post aboice I was being honest about everything, not a smart ass. Sorry if I offened you. Thanks so much for all you help thus far.

    Did you see anything on the thyroid test's I have done and how do you test adrenal's? Thanks so much
    Your Dr is missing 80% of the thyroid puzzle like many do. This is why people never get better from many MD and DO. They are just plain lazy and do not want to look for cause.
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    I met with a ND and MD today, they run a HRT and Natural Healing Clinic in Boulder, Co. We went over blood work and hear is what the ND had to say. He wanted to do a "toxic metal I V" and "toxic metal test". He also wanted to test SHBG. He guessed my SHGB would be high 60-80 was his guess going off of the test to free test ratio. He also wanted to re-test my IGF-1, which he thinks is on the low side for my age. I got my IGF-1 tested on 7-15-2009 it came back
    IGF-1 146 (115-307)
    he said anything below 150 raises a red flag for him????
    I am not sure how you treat low IGF, we really didn't get into that.
    He said depending on how those tests come back he would put me on Test Cream and HCG. I would like to get to the root of the problem, but I am starting to lose hope, is HRT my only option???

    Thanks
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    Also, get your serum zinc and 25-hydroxy (vitamin D3) checked.
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    I have been doing a ton and ton of research and I think I am going to look deeper into thyroid. I found the coolest site with a ton of cool info, please see below
    http://www.stopthethyroidmadness.com/long-and-pathetic/
    I had no idea how the TSH testing was, what it looked into and how relatively new this test is. It is amazing all the symptoms of Hypothyroid, I have about every one of them. I am going to do test 4 on the following link http://www.stopthethyroidmadness.com/adrenal-info/
    I will do if for 5 days as suggested and post results for you guys each day. Let me know what you guys think.
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    I'm 32 and had all the same test from the doc with same results. my doc put me on depo test 3 time aweek 40mg on monday 40mg wednesday 60mg on friday with 1/4mg of arimidex a week. after 4 weeks my results came back perfect
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    You need to get a full thyroid panel done. TSH, total and free T3/T4 and reverse T3 as well.

    A 4x day saliva cortisol also.

    If you get those fixed (assuming there's a problem) your T very may well bounce back.

    Growth hormone is low but that is the last in line...if you sort out the others (especially thyroid/adrenal) it would not be a surprise to see it increase.
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    I think I am going to do the "Premium Thyroid Function Blood Profile with TSH" from Health Check USA which works with Lab Core. This test includes, Free T3, Free T4, TSH, T3 Uptake, T4 Total, and T7. I am thinking of also including the 4X Saliva Cortisol test. I was also thinking of including SHBG but from what I have read Hypothyroidism leads to elevated SHBG so I am not sure if this would be worth it. If I have thyriod issues causing elevated SHBG this could explain the low free test. Then in theory treating the thyroid would lower SHBG freeing up some of the bound test????

    Please let me know if you guys think I should throw in any other test? Thanks so much for everyone's help
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    I was thinking of throwing in,
    Vitamin B12 with Folate Blood Test
    What do you guys think, let me know.
    I am actually starting to see some light at the end of the tunnel. If you guys think the above test would be good to run let me know and I will keep you guys updated and post results. Thanks again.
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    Those tests would be good...make sure you get a reverse T3 as well. This is where "hidden hypothyroidism" comes from.

    I would check out privatemdlabs.com typically the cheapest pricing in my experience.
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    I did my temperature testing today is day 1 of the 5 day testing, results below.

    5:30 a.m. upon rising- 96.4
    8:30 a.m.- 97.6
    12:00- 96.3
    3:00 p.m.- 96.6

    What do you guys think?? Thanks
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    I'm also 32 so I can relate. Over the last two years, I've made much progress, but still have a long way to go.

    I've had the most success with HCG. I've also seen positive results from combo of hcg and compounded gel. I question the effectiveness of the brand (APP) that I'm currently using. And will be beginning Pregnyl in the next few days.

    As GimmeT recommended check out your RT3 level. Mine was higher than it should be. Which I'm pretty sure stress is the underlying cause. I'm currently considering options such as T3 to combat this.

    Also, your temps do seem too low. I'm sure correcting some of your thyroid/adrenal problems would go a long way fixing this. The guys on this board are awesome and everyone will try to help you out as much as possible.
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    Day 2
    6:00 a.m.- 96.7
    9:00 a.m.- 96.8
    12:00- 96.8
    4:00- 96.9

    I will post day 3 later today. Is this normal temp ranges?? I thought you were supposed to be at 98.6.?? Thanks
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    Quote Originally Posted by Bryce720 View Post
    I think I am going to do the "Premium Thyroid Function Blood Profile with TSH" from Health Check USA which works with Lab Core. This test includes, Free T3, Free T4, TSH, T3 Uptake, T4 Total, and T7. I am thinking of also including the 4X Saliva Cortisol test. I was also thinking of including SHBG but from what I have read Hypothyroidism leads to elevated SHBG so I am not sure if this would be worth it. If I have thyriod issues causing elevated SHBG this could explain the low free test. Then in theory treating the thyroid would lower SHBG freeing up some of the bound test????

    Please let me know if you guys think I should throw in any other test? Thanks so much for everyone's help
    waste of money
    t3 uptake worthless
    tsh worthless
    t7 worthless.

    add total t3, reverse t3

    You better go back and do your research low SHBG indicates hypthyroidism.
    Thisis why you need some one to properly handle your case because trying to fix your self and self diagnose is going to get you into more trouble. Instead of nicke and diming on test you could have had 1/2 cost covered to goto see a specialist,
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
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    I would love to find a specialist in my area but have yet to do so. I am on a limited budget and just can't afford to fly out of state and meet with someone. I know you can't put a price on health, but I just don't have a ton of money at this point. Can you recommend anyone in the Colorado area?? Thanks so much for everyone's help.
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    Did u do cycles in the passed that messed thing up for u. i've been working for two years with doc's to get back to normal. after i mess around with cycle.
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    I never have done cycle. I did take M1T which could have screwed me up though. I know most of the PH's are probably harder on you than a properly done cycle.
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    Day 4
    5:00 a.m.- 96.0
    8:00 a.m.- 96.7
    11:00 a.m.- 96.8
    3:30- 96.9

    So what do you guys think of the temps thus far, I have one day left. Thanks
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    So I got my results back and they're listed below

    Thyroid Antibodies
    TP0- 16 (0-34)
    AB- <20 (0-40)
    Vitamin B-12- 1075 (211-911)
    Free T4- 1.70 (.82-1.77)
    TSH- 1.050 (.450-4.5)
    Vitamin D- 42.2 (32.0-100.0)
    Estradoil- 9.5 (7.6-42.6)
    Reverse T3 380 (90-350)
    Ferritin, Serum- 868 (22-322)
    Free T3- 3.0 (2.0-4.4)
    SHBG- 55.7 (14.5-48.4)

    WOW how many things can go wrong at once. I think the SHBG would explain my low free test and I think the SHBG is what is killing my sex drive, desire and so on. I have been told that reverse T3 is the hidden Hypo. high reverse T3 mimics hypothyroidism and drops your body temperature/slows your metabolism. even if you are not clinically hypo according to your freeT3 and freeT4, you are still EFFECTIVELY HYPOTHYROID because your reverse T3 is blocking your freeT3 from working.

    I am not sure what to do or where to go from here. I guess I am at least headed in the right direction it is just frusterating. Why in the hell would my SHBG be so high and how do I lower it???
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    This is interesting....Man I hope you get this figured out....and keep us posted please.
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    Yoshi, thanks for you concern I will most definetly keep you posted. I also wanted to thank Matrix he has been so much help with everything. I would not be to this point in testing if it wasn't for him.

    I think we're going to look into "Hemochromatosis" with those super, super high ferritin levels. This would explain about every symptom I have
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    Bryce720

    Reverse T3 380 (90-350)
    Ferritin, Serum- 868 (22-322)
    SHBG- 55.7 (14.5-48.4)


    ============================== =========================
    Make a copy of this post and take it with you when visiting
    hematologist and latter a doctor that will help you with thyroid and TRT.

    ============================== =========================
    You have (at least) three problems.

    You have thyroid problem,
    but before we would treat that, you need to check and (possibly but highly likely) correct
    adrenal issues and thyroid support
    before
    you can (SAFELY) start on T3 supplementation (THAT YOU SORELY NEED).

    Whatever you do, DO NOT use ANY T4.
    ============================== ======
    Make appointment with Hematologist

    You may have hemachromatosis,
    and
    you definitely have a high ferritin (one of the pre-requisites)
    most likely you will need phlebotomies
    if you have please post, values of
    hematocrit (Hct)
    or
    hemoglobin (Hg)
    they are part of (Complete Blood Count CBC panel)
    ============================== ========

    Your testicles will newer be able to make enough testosterone.
    Whatewer you will make, will be immediately absorbed by your high SHBG (we have to get it down naturally, NEWER Danazol or Stanozolol)
    but
    you should not do testosterone suplementation
    until
    your Hct/Hg/Ferritin are in check
    testosterone raises iron
    you cannot afford to use testosterone at this time
    first
    have your Hct/Hg/Ferritin uner control
    ============================== ============================

    Sorry to hear that you also have $$$ problems.
    I am not clairvoyant but I will try to take $$$ into consideration.
    I am usually on dr John's board and do not check on this board to often.
    If you PM me, I will read any new info that you may post, and you want me to read it.

    My suggestions for you:
    ==================
    ASAP
    Go to nearest Red Cross or doc who can check your hemoglobin in his office (finger prick, similar to glucose check).
    HGB g/dL MALES: (13.2-17.1)
    If you are over 16.9 ask them to take one pint of your blood, or (sometimes available) double dose of RBC.
    Your goal is Hbg=16
    anything over 16.5 is already high

    when you are no more than 16.5, when checking every two weeks, you are ready to introduce testosterone
    ==================
    Ask doctor to sign this script (between lines) for you.
    Print this part and ask him to sign it.
    Do not give blood at doc's office.
    Go to Quest Diagnostics Patient Center
    ---------------------------------------------------------------------------------------------------
    1 --------- Comprehensive Metabolic Panel w/EGFR
    2 --------- CBC w/ diff/PLT
    8 --------- C-Reactive Protein (CRP), Highly Sensitive, CSF - (17401X)
    9 --------- Fibrinogen
    10 --------- Homocysteine, cardio
    12 --------- Iron and Iron Binding Capacity (7573X) - (356N)
    13 --------- Iron, Total (571X) - (24984P)
    14 --------- Ferritin (457X) - (22764P)
    15 --------- Transferrin (891X) - (30346P)
    16 --------- Folate, RBC & Hematocrit - (1768N)
    17 --------- Hemoglobin A1c (496X) - (45484P)
    31 --------- DHEA Sulfate 402X
    32 --------- Aldosterone
    33 --------- Renin Activity, Plasma
    34 --------- ACTH, Plasma
    35 --------- Cortisol Binding Globulin (Transcortin) (37371X)
    36 --------- 8AM/4PM---Cortisol, Free and Total, LC/MS/MS (37077X)
    37 --------- Prolactin - (746X)
    46 --------- Ceruloplasmin (326X)
    ----------
    244.9 ----- 257.2 ----- 780.79
    250.00 ----- 272.4 ----- 788.41
    250.01 ----- 601.9 ----- 253.3
    255.4 ----- 780.4 ----- 255.8
    783.9 -----
    --------------------------------------------------------------------------------------------------

    You also need to have

    Spectracell-5000
    FIA™ Comprehensive Profile 5000

    complete panel done.
    Ask for script and have it done at place that serves Spectracel (see their web site).

    You want test that consist of two (complete) panels.
    http://www.spectracell.com/product-specs/

    complete MicroNutrient test
    and
    Lipoprotein Particle Profile

    You can have this test done all by your self ($350)
    or just few $$ if you get the script (and have insurance)

    ----------------------------------------------------------------------------------------------
    You are ABSOLUTELY not ready YET for medicines below, but this is where you are heading, so

    Speak with your doc and get him ready to write scripts for:

    adrenal/thyroidsupport
    Cortef-40mg/day(divided)=HC(hydrocortisone ) or Medrol-6mg/day
    Cytomel-T3 25mg (up to 4 tabs/day)(divided)

    Androgens
    HCG-(in very small vials, 2000iu)
    Testosterone Cypionate or Enanthate 200mg/mL (or Androgel)

    EOD, EveryOtherDay schedule
    one day (HCG + T)shots, next day free of shots

    HCG=250iu
    T-shot=60mg=30units=210mg/week

    both shots done using this syringe (no script reqd)
    BD Ultrafine II U-100 Insulin Syringe 31 Gauge 3/10cc 5/16inch Short Needle--1/2 Unit Markings 100/b

    also, (but possibly we will try to avoid need for it by using small and frequent dosing of (T&HCG):
    Arimidex(liquid)=Liquidex(liqu id)=Anastrozole(liquid)
    =======================

    The testing above will uncover your weak spots and help to design list of supplements for you.
    After 1-2 months on those supplements
    after iron status is clarified and under control
    you will be allowed to start on above medications.

    Good luck.

    ================
    /
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    Thanks so much for all the help Jansz. So I just got back from my doctor and have my blood work.

    TRANSFERRIN SAT
    Iron 117 (45-182)
    Transferrin Sat 34 (20-50)
    Transferrin 249 (215-365)

    LH 4.3 (1.7-8.6)
    FSH 2.5 (1.5-12.4)

    Iron Serum 119 (40-155)

    CBC
    wbc 5.4 (4-10.5)
    rbc 4.99 (4.20-6.0)
    hemoglobin 15.5 (13.0-18.0)
    hematocrit 44.7 (37-55)
    mcv 90 (80-98)
    mch 31 (27-34)
    mchc 34.6 (32.0-36.0)
    rdw 13.4 (11.7-15)
    platelets 158 (140-415)
    neutrophils 52 (40-74)
    lymphs 38 (14-46)
    monocytes 7 (4-13)
    eos 3 (0-7)
    basos 0 (0-3)
    neutrophils absolute 2.8 (1.8-7.8)
    lymphs absolute 2.1 (.7-4.5)
    monocytes absolute .4 (.1-1.0)
    eos absolute .2 (.0-.4)
    baso absolute .0 (.0-.2)

    Ferritin Serum 828 (22-322)

    So I am guessing at this point we can rule out hemachromatosis. Now it is a matter of figuring out what is going on. I have read high ferritin and regular iron can be link to thyroid?? Have at it guys let me know what you think.
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    Quote Originally Posted by Bryce720 View Post
    Thanks so much for all the help Jansz. So I just got back from my doctor and have my blood work.

    TRANSFERRIN SAT
    Iron 117 (45-182)
    Transferrin Sat 34 (20-50)
    Transferrin 249 (215-365)

    LH 4.3 (1.7-8.6)
    FSH 2.5 (1.5-12.4)

    Iron Serum 119 (40-155)

    CBC
    wbc 5.4 (4-10.5)



    rbc 4.99 (4.20-6.0)
    hemoglobin 15.5 (13.0-18.0)
    hematocrit 44.7 (37-55)


    mcv 90 (80-98)
    mch 31 (27-34)
    mchc 34.6 (32.0-36.0)
    rdw 13.4 (11.7-15)
    platelets 158 (140-415)
    neutrophils 52 (40-74)
    lymphs 38 (14-46)
    monocytes 7 (4-13)
    eos 3 (0-7)
    basos 0 (0-3)
    neutrophils absolute 2.8 (1.8-7.8)
    lymphs absolute 2.1 (.7-4.5)
    monocytes absolute .4 (.1-1.0)
    eos absolute .2 (.0-.4)
    baso absolute .0 (.0-.2)

    Ferritin Serum 828 (22-322)


    So I am guessing at this point we can rule out hemachromatosis. Now it is a matter of figuring out what is going on. I have read high ferritin and regular iron can be link to thyroid?? Have at it guys let me know what you think.
    You do have hemachromatosis.
    You are failing test #2

    http://www.ironoverload.org/diagnosis.html
    Test # 2
    Using the blood from the first draw, next check the amount of storage iron - Ferritin (SF)

    Safe range = 5-150

    ============================== ==================

    You should see doctor, hematologist, ASAP.
    You will have to undergo multiple phlebotomies to correct/control this issue.

    In the mean time read:

    http://www.ironoverload.org/diagnosis.html
    http://www.ironoverload.org/anemia.htm
    http://www.nlm.nih.gov/medlineplus/e...cle/000327.htm


    .....................
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    Thanks so much. I am so sorry, I don't really understand the test and how it proves I have hemachromatosis. Maybe I am not reading something right?? Thanks so much I can usually figure this stuff out, but this is super confusing to me. Thanks
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    Quote Originally Posted by Bryce720 View Post
    Thanks so much. I am so sorry, I don't really understand the test and how it proves I have hemachromatosis. Maybe I am not reading something right?? Thanks so much I can usually figure this stuff out, but this is super confusing to me. Thanks
    Ferritin, Serum- 868 (22-322)
    Ferritin Serum 828 (22-322)

    You did two ferritin tests, we know for sure that your ferritin is very high.

    Please make appointment with doctor who specialize in blood disorders,
    hematologist.

    Follow his advice.

    You may want to go first to your local GP and ask for name.

    ...
    ...
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    I will make appointment and try to get into tomorrow. So are you saying you still think it is Hemo. I still don't understand, the test and how it works?? I just want to go in to the Hematologist educated. Thanks
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    you are Ferritin Serum 828 (22-322)

    the safe range is 5-150, nice work jansz

    I think im right about that
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    I am not sure I understand. Levels should be 22-322, latest testing I was 828 which I am aware is super high. I am going to try to get into the hematologist today and see why that might be. From what I am aware of when it comes to hemachromatosis, I would have high transferrin and total iron not just ferritin. To be honest I wish it was just hemachromatosis then I could just take some blood out every now and then and be over with this. But once again it is not that simple and were going to have to dig deeper. Thanks so much for all the help thus far.
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    Quote Originally Posted by Bryce720 View Post
    I am not sure I understand. Levels should be 22-322, latest testing I was 828 which I am aware is super high. I am going to try to get into the hematologist today and see why that might be. From what I am aware of when it comes to hemachromatosis, I would have high transferrin and total iron not just ferritin. To be honest I wish it was just hemachromatosis then I could just take some blood out every now and then and be over with this. But once again it is not that simple and were going to have to dig deeper. Thanks so much for all the help thus far.
    We still do not know your UIBC (test #3)

    To have hemachromatosis you have to fail one out of three tests.

    Look at link I have given you in post #28

    http://www.ironoverload.org/diagnosis.html


    Test # 1
    After a 12 hour fast, measure Total Iron Binding Capacity (TIBC) and the Serum Iron (SI). To achieve the percentage of Saturation you divide the TIBC into SI..

    Serum Iron SI
    ------- = Yields Transferrin Saturation (TS)
    Total Iron Binding TIBC or in some labs Percentage of Saturation
    Capacity
    Safe range = 12-44%

    Any values above this range must be considered diagnostic for hemochromatosis and should cause immediate protocol treatment. Any values far below this range may be a sign of bleeding ulcers, chronic infection or cancer. Physicians should look for the cause of anemia.

    Test # 2
    Using the blood from the first draw, next check the amount of storage iron - Serum Ferritin (SF)

    Safe range = 5-150

    A hemochromatosis patient needs to be at the lowest end of this range. We say below 10.
    This needs to be the treatment goal.

    Test # 3
    This next test is given less frequently. It is initialized as UIBC. It stands for unbound iron binding capacity.
    Safe range is above = 146

    If a patient checks below this test value, then he or she needs to be treated for their
    hemochromatosis or their other iron overload condition.
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    Thank goodness I have an appointment with an Hematologist today at 3:20. I transferred all my records and she will have them for review. Obviously she will see the super high ferritin, I am assuming she will know where to go from here?? But assuming drs have a clue has got me no where thus far. Should I ask about running the UIBC test if it is not mentioned?? Or is there anything else to bring up. Thanks and wish me luck.
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    Quote Originally Posted by Bryce720 View Post
    Thank goodness I have an appointment with an Hematologist today at 3:20. I transferred all my records and she will have them for review. Obviously she will see the super high ferritin, I am assuming she will know where to go from here?? But assuming drs have a clue has got me no where thus far. Should I ask about running the UIBC test if it is not mentioned?? Or is there anything else to bring up. Thanks and wish me luck.
    I assume that your problem is just what the hematologist is dealing with day in and day out.

    I think number of phlebotomies is ahead of you, most likely just the RBC cells.

    From what I hear about, I would rather stay away from chelating iron out.

    Good luck.
    Let me know what she says.

    ....
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    Quote Originally Posted by Bryce720 View Post
    Thank goodness I have an appointment with an Hematologist today at 3:20. I transferred all my records and she will have them for review. Obviously she will see the super high ferritin, I am assuming she will know where to go from here?? But assuming drs have a clue has got me no where thus far. Should I ask about running the UIBC test if it is not mentioned?? Or is there anything else to bring up. Thanks and wish me luck.
    I view seeing a dr like a good attorney would cross examine a defendant. Try to ask as many questions that you already know the answer to as you can. That will insure she is both competent and honest.

    good luck
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    So I went to see the Hematologist and it was interesting to say the least. She was super confused about the high ferritin. She said it could be anything from liver, to lymph or inflamatory??? She is leading toward something rumatory sp??? since my cbc came back great. We did however draw 9 viles of blood. Please see below, I have no idea what most of these are.

    CMP
    PT/INR
    LDH
    CRP
    CBC
    ESR
    B2 Micro
    APTT
    RF
    ANA
    Hepatitis Panel
    Hemachromotosis Genetic test (HFE Gene Test)

    I should have 90% of these back tomorrow. I will post results ASAP. Does it look like she left anything out?? Thanks so much for all the help.
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    Quote Originally Posted by Bryce720 View Post
    So I went to see the Hematologist and it was interesting to say the least. She was super confused about the high ferritin. She said it could be anything from liver, to lymph or inflamatory??? She is leading toward something rumatory sp??? since my cbc came back great. We did however draw 9 viles of blood. Please see below, I have no idea what most of these are.

    CMP
    PT/INR
    LDH
    CRP
    CBC
    ESR
    B2 Micro
    APTT
    RF
    ANA
    Hepatitis Panel
    Hemachromotosis Genetic test (HFE Gene Test)

    I should have 90% of these back tomorrow. I will post results ASAP. Does it look like she left anything out?? Thanks so much for all the help.
    CMP
    PT/INR
    LDH
    CRP
    CBC
    ESR
    B2 Micro
    APTT
    RF
    ANA
    Hepatitis Panel
    Hemachromotosis Genetic test (HFE Gene Test)

    ============================== ============================== ========================
    Comprehensive Metabolic Panel
    The CMP includes:

    Glucose
    Calcium
    Both increased and decreased levels can be significant.

    Proteins

    Albumin
    Total Protein
    Albumin, a small protein produced in the liver, is the major protein in serum. Total protein measures albumin as well as all other proteins in serum. Both increases and decreases in these test results can be significant.

    Electrolytes

    Sodium
    Potassium
    CO2 (carbon dioxide, bicarbonate)
    Chloride
    The concentrations of sodium and potassium are tightly regulated by the body as is the balance between the four molecules. Electrolyte (and acid-base) imbalances can be present with a wide variety of acute and chronic illnesses. Chloride and CO2 tests are rarely ordered by themselves.

    Kidney Tests

    BUN (blood urea nitrogen)
    Creatinine
    BUN and creatinine are waste products filtered out of the blood by the kidneys. Increased concentrations in the blood may indicate a temporary or chronic decrease in kidney function. When not ordered as part of the CMP, they are still usually ordered together.

    Liver Tests

    ALP (alkaline phosphatase)
    ALT (alanine amino transferase, also called SGPT)
    AST (aspartate amino transferase, also called SGOT)
    Bilirubin
    ALP, ALT, and AST are enzymes found in the liver and other tissues. Bilirubin is a waste product produced by the liver as it breaks down and recycles aged red blood cells. All can be found in elevated concentrations in the blood with liver disease or dysfunction.
    ============================== ============================== ========================
    Prothrombin Time and International
    PT and INR
    Since the Prothrombin time (PT) evaluates the ability of blood to clot properly, it can be used to help diagnose bleeding. When used in this instance, it is often used in conjunction with the PTT to evaluate the function of all coagulation factors. Occasionally, the test may be used to screen patients for any previously undetected bleeding problems prior to surgical procedures.
    ============================== ============================== ========================

    Lactate dehydrogenase, Total and Isoenzymes
    LDH

    A total LDH level may be ordered, along with other tests, as a screening test when your doctor suspects some kind of cellular or tissue damage. If the total LDH is elevated, then he may order LDH isoenzymes or, more commonly, other tests such as ALT, AST or ALP to help diagnose the condition and to help determine which organs are involved. Once the acute or chronic problem is diagnosed, total LDH levels may be used at regular intervals to monitor its progress and/or resolution.
    ============================== ============================== ============================
    CRP Formal name: C-Reactive Protein Related tests: High-sensitivity C-reactive protein (hs-CRP);
    CRP
    C-reactive protein (CRP) is an acute phase reactant, a substance made by the liver and secreted into the bloodstream within a few hours after the start of an infection or inflammation. Increased levels are observed after a heart attack, in sepsis, and after a surgical procedure. Its rise in the blood can also precede pain, fever, or other clinical indicators. The level of CRP can jump a thousand-fold in response to inflammation and can be valuable in monitoring disease activity.
    ============================== ============================== ==================
    Complete Blood Count
    CBC

    WBC ====== White Blood Cell
    % Neutrophil ====== Neutrophil/Band/Seg/Gran
    Lymphs ====== Lymphocyte
    % Mono ====== Monocyte
    % Eos ====== Eosinophil
    % Baso ====== Basophil
    Neutrophil ====== Neutrophil/Ban/Seg/Gran
    Lymphs ====== Lymphocyte
    Mono ====== Monocyte
    Eos ====== Eosinophil
    Baso ====== Basophil
    RBC ====== Red Blood Cell
    Hgb ====== Hemoglobin
    Hct ====== Hematocrit
    MCV ====== Mean Corpuscular Volume
    MCH ====== Mean Corpuscular Hemoglobin
    MCHC ====== Mean Corpuscular Hemoglobin Concentration
    RDW ====== RBC Distribution Width
    Platelet ====== Platelet
    MPV ====== Mean Platelet Volume
    ============================== ============================== ============================== =
    Erythrocyte sedimentation rate
    ESR
    A physician usually orders an ESR test (along with others) to evaluate a patient who has symptoms that suggest polymyalgia rheumatica or temporal arteritis, such as headaches, neck or shoulder pain, pelvic pain, anemia, unexplained weight loss, and joint stiffness. There are many other conditions that can result in a temporary or sustained elevation in the ESR.

    Since ESR is a nonspecific marker of inflammation and is affected by other factors, the results must be used along with the doctor's other clinical findings, the patient’s health history, and results from other appropriate laboratory tests. If the ESR and clinical findings match, the doctor may be able to confirm or rule out a suspected diagnosis.
    ============================== ============================== ===================
    Serum B2 Micro globulin

    not sure

    B2 Micro
    ============================== ==========
    Activated Partial Thromboplastin Time
    APTT
    The PTT test is ordered when someone has unexplained bleeding or clotting. Along with the PT (which evaluates the extrinsic and common pathways of the coagulation cascade), the PTT is often used as a starting place when investigating the cause of a bleeding or thrombotic episode.
    ============================== ============================== ===============
    Rheumatoid Factor
    RF
    The rheumatoid factor (RF) test is primarily used to help diagnose rheumatoid arthritis (RA) and to distinguish it from other forms of arthritis and other conditions that cause similar symptoms of joint pain, inflammation, and stiffness. It may be ordered along with other autoimmune-related tests, such as an ANA (antinuclear antibody), along with other markers of inflammation, such as a CRP (C-reactive protein) and ESR (erythrocyte sedimentation rate), and along with a CBC (Complete Blood Count) to evaluate the body’s blood cells
    ============================== ============================== =================
    Antinuclear Antibody test
    ANA
    The ANA test is ordered to help screen for autoimmune disorders and is most often used as one of the tests to diagnose systemic lupus erythematosus (SLE). Depending on the patient's symptoms and the suspected diagnosis, ANA may be ordered along with one or more other autoantibody tests. Other laboratory tests associated with presence of inflammation, such as erythrocyte sedimentation rate (ESR) and/or C-reactive protein (CRP) may also be ordered. ANA may be followed by additional tests that are considered subsets of the general ANA test and that are used in conjunction with the patient's clinical history to help rule out a diagnosis of other autoimmune disorders.
    ============================== ============================== =================
    HEPATITIS PANEL

    Hepatitis A IgM
    Hepatitis B Core Antibody, Total
    Hepatitis B Surface Antibody, Qualitative
    Hepatitis B Surface Antigen
    Hepatitis B Surface Antigen Confirmation
    Hepatitis C Antibody
    ============================== ============================== =====================
    Hemachromotosis Genetic test (HFE Gene Test)

    HEREDITARY HEMOCHROMATOSIS
    __DNA Mutation Analysis (UOM )
    Hereditary hemochromatosis (HH) is an autosomal recessive
    disorder of iron metabolism that results in iron overload
    and potential organ failure. It is one of the most common
    genetic disorders in individuals of European-Caucasian
    ancestry, with an estimated carrier frequency of 10%. HH is
    caused by mutations in the HFE gene. Most individuals with
    HH (60%-90%) are homozygous for the C282Y mutation. A
    smaller percentage of affected individuals are either
    compound heterozygous for the C282Y and H63D mutations
    (3%-8%), or homozygous for the H63D mutation (approximately
    1%).
    ============================== ============================== ==

    ///
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    Thanks so much for all the info, WOW sounds like were going to get a ton of info back. The Hematologist wants to see me on the 26th, but I signed a form so I have access to my blood tests right away. The lab said most of my blood work should be back tomorrow and I can pick them up. To be honest I am a little scared now I know I can pick these tests and post them up and you guys are going to do your best to break them down.

    These tests are a little out of my league at this point. I guess I am just scared to get the test results that could mean 100 different things from liver cancer to an infection and trying to figure that out can be scary. I really don't know what to do?? Maybe someone else has been through this and can help
  

  
 

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