Huge SHBG, need advice

[romanul]

I have
SHBG 87.7 (14.5-48.4 nmol/l)

And, since january, zero sexual life.

Other results

Testosteron 5.78 (1.95-11.38 ng/ml)
Free testosteron 17.53 pg/ml (3.84- 34.17)
TSH 1.35 (Ui/ml 0.34-5.6)
LH 3.47 mUi/ml (1.24-8.62)
Estradiol OK

Prolactine 6.63 ng/ml (2.6-13.1)
And, in another test done in a different laboratory -prolactine 11.62 but with another levels of normality (2.46-19.40 ng/ml)

Glicemy 75 (74-106 mg/dl)
Cortizol 15.4 (3.7-19.4 ug/dl)
VSH 14 (2-15 mm/h)
Magnezium 2.1 (1.6-2.6)
T3 0.83 (0.58-1.59 ng/l)
T4 6.04 (4.87- 11.72 ug/dl)

The problems appeared 3 years ago. I used to have a strong libido and then, suddenly, I sexually died.
Zero sexual desire. The situation lasted for 6 month. Then, somehow, my libido returned strongly for a month. Then, again, the libido diminished. I had weak erection, lasting too little. I thought there was something with my hormones, and i did nothing, waiting for my body to fix it somehow. A years and a half I lived like that. But, as i said, from january, the situation worsened and I died again. Doctors say I should see a psichoterapeut because they can not explain this huge SHBG. I found your forum and you seem to know more about these problems.
I am 32, I am 90 kg weight, I am tall.
I have a story of masturbatory practice and, until 3 years ago, a normal sexual life.
I used to masturbate one time in a day. Could it be the cause of my problems?

 

[Pirate!]

Find a better doctor. You may have an issue involving 5-alpha reductase activity.

 

[The Matrix]

Find a better doctor. You may have an issue involving 5-alpha reductase activity.

High SHBG occurs in
1) low fat diets higher fiber
2) low protein or malnutritoin
3) starvation
4) liver disease
5) excessive alcohol abuse
6) low testosterone
7) low carb diet
8) insulin deficiency
9) low GH
10) low cortisol production

 

[EasyEJL]

I'm confused as to how your free testosterone can be that high with that low of a total testosterone, and that high of an shbg. are you looking to just lower shbg herbally/chemically as a try or are you looking to determine root cause? medical studies have shown that 20mg of winstrol taken 1x a day for just 3 days can cut shbg as low as in half.

 

[mooch2321]

try some slin

 

[Bigbuttchicks]

was about to say slin but someone beat me to it

 

[Bigbuttchicks]

insulinis one ofthe most powerful anabolic,anticatbolic hormones on the planet

 

[The Matrix]

insulinis one ofthe most powerful anabolic,anticatbolic hormones on the planet

Great advice guys Typical meathead answer....make the guy have more issues then hes already has. May be he just needs to eat more carbs ever figure that. Winstrol is not a long term solution only temporary. Need to look to see why it is elevated. Danazol would be a better choice of 25-50 mgs every day..

 

[JanSz]

I have
SHBG 87.7 (14.5-48.4 nmol/l)

And, since january, zero sexual life.

Other results

Testosteron 5.78 (1.95-11.38 ng/ml)
Free testosteron 17.53 pg/ml (3.84- 34.17)
TSH 1.35 (Ui/ml 0.34-5.6)
LH 3.47 mUi/ml (1.24-8.62)
Estradiol OK

Prolactine 6.63 ng/ml (2.6-13.1)
And, in another test done in a different laboratory -prolactine 11.62 but with another levels of normality (2.46-19.40 ng/ml)

Glicemy 75 (74-106 mg/dl)
Cortizol 15.4 (3.7-19.4 ug/dl)
VSH 14 (2-15 mm/h)
Magnezium 2.1 (1.6-2.6)
T3 0.83 (0.58-1.59 ng/l)
T4 6.04 (4.87- 11.72 ug/dl)

The problems appeared 3 years ago. I used to have a strong libido and then, suddenly, I sexually died.
Zero sexual desire. The situation lasted for 6 month. Then, somehow, my libido returned strongly for a month. Then, again, the libido diminished. I had weak erection, lasting too little. I thought there was something with my hormones, and i did nothing, waiting for my body to fix it somehow. A years and a half I lived like that. But, as i said, from january, the situation worsened and I died again. Doctors say I should see a psichoterapeut because they can not explain this huge SHBG. I found your forum and you seem to know more about these problems.
I am 32, I am 90 kg weight, I am tall.
I have a story of masturbatory practice and, until 3 years ago, a normal sexual life.
I used to masturbate one time in a day. Could it be the cause of my problems?

Check your adrenals, make sure that they are working ok.
Do 4x saliva test
If indicated use HC

Above is first.

Second
You do have problem with thyroid.

Looking at
T3 0.83 (0.58-1.59 ng/l)
T4 6.04 (4.87- 11.72 ug/dl)

you should have TotalT3~=(1.59-0.83)*7/8+0.58=1.245

To get there you should try first good adrenal and thyroid support.

Adrenal-Support
vitamin B6,
Vitamin B5 - pantothenic acid
vitamin C
Vit D
calcium,
magnesium,
potassium,
manganese,
zinc

Thyroid Support
Iodine
Selenium
Zinc
Vitamin D
Vitamin E
Antioxidants
Essential Fats
Amino Acids

Assuming that you comply with all above
and you still have TotalT3 too low

at that time you should start supplementation with thyroid hormones.

First do these tests, and correct defficiencies:
-------------------------------
VITAMIN A, E, B3, B12
Vitamin D, 25-Hydroxy, LC/MS/MS
T3, Total
T4, Total (Thyroxine)
T3, Free
T4,Free
T3, Reverse
Ultrasensitive TSH
Thyroid Peroxidase and Thyroglobulin Antibodies
Insuline, serum
IGF Binding protein-3
IGF-1
DHEA Sulfate
Aldosterone
Renin Activity, Plasma
ACTH, Plasma
Cortisol Binding Globulin (Transcortin)
8AM/4PM/10PM---Cortisol, Free and Total, LC/MS/MS
Prolactin

--------------------------

If you still have too low TotalT3

Supplement with thyroid hormone

Cytomel-T3---75mcg/day (divide 3x/day)

Make sure that you are not taking anything containing T4-hormone.

After about 3-4 months you may want to check your

TotalTestosterone
SHBG

If TT still low and SHBG still high

Make sure that you DO NOT use Danazol or Stanozolol

Do following protocol (EVERY DAY)

Get
HCG (best if in portions of 2000iu per vial, like HUCOG-2000iu)
Testosterone Enanthate or Cypionate
BD Ultrafine II U-100 Insulin Syringe 31 Gauge 3/10cc 5/16inch Short Needle

HCG-shot=150iu
T-shot=40mg=20units

That is relatively large weekly testosterone dose, 280mg/week
Its purpose is to elevate your TotalTestosterone.

High level of TT should result in lowering your SHBG.

Frequent (every day) testosterone injections should prevent high Estradiol (E2)

You will have to monitor E2 anyhow and if need arise, use Arimidex (Anastrozole) to keep it in desired range.

-----------------

There is more.

Lets see if you can accomplish above.


....
If you are able, get do blood testing per my list of tests.
Post #44, between blue lines, here:

http://anabolicminds.com/forum/male-anti-aging/66268-jans-bloodtest-april13-2.html


...

 

[ram23]

Do following protocol (EVERY DAY)

Get
HCG (best if in portions of 2000iu per vial, like HUCOG-2000iu)
Testosterone Enanthate or Cypionate
BD Ultrafine II U-100 Insulin Syringe 31 Gauge 3/10cc 5/16inch Short Needle

HCG-shot=150iu
T-shot=40mg=20units


...

so are you recommending he do the testosterone shots subcutaneously with and insulin pin? is subq test shots safe and a good way to go? i've heard of this recently but don't know of anyone who does this.

 

[EasyEJL]

now you do, cause Jan does

studies have shown it to be effective as well. Not so much the first few weeks, but once levels have stabilized its better than IM

 

[JanSz]

now you do, cause Jan does

studies have shown it to be effective as well. Not so much the first few weeks, but once levels have stabilized its better than IM

I do (T & HCG) on EOD schedule.

It is my third year doing it.

For about year and half I do not need to use Arimidex.

My schedule

T-shot=50mg
HCG-shot=(350-400)iu

Both shots done on the same day, next day free of shots.

69yo, wood every night (justify the inconvenience of frequent shots).
....

 

[Philec48]

Janz, do you find that sub-q T translates to less aromatization to E2 as opposed to im T?

Thanks,

Phil

 

[romanul]

thank you all

I have a good picture, now, of what I have to do in the next months.


thank you JanSz. You did great effort to write those steps for me.
I hope there is a hope for me at the end of this way.

 

[JanSz]

Janz, do you find that sub-q T translates to less aromatization to E2 as opposed to im T?

Thanks,

Phil

Direct answer is no.

To prevent or slow down aromatization divide your weekly dose into seven smaller daily doses.

For example, my case

I do total of 175mg/week testosterone.

Because I divide weekly dose into smaller 50mg shots and do those shots every other day,
I do not need Arimidex, my E2 stays in good range.

If instead I did one 175mg shot per week,
I would have much higher E2
and will be forced to use Arimidex to control it.

Controlling E2 while on weekly roller coaster is difficult and 100% people fail at it from time to time.

I found EOD (T & HCG) shots a small price to pay for a peace of mind about E2.


...

When doing small volume testosterone injections (up to about 200mg/shot is small), it make no difference if done shallow (1/4-1/2)" or deep (1-1.5)".

Large and long needles are artifact from steroid use where much lager doses are used at one time.


...

...

 

[Philec48]

Thanks Janz. Another question, when I inject hcg .25cc using a 31g 5/16" sub-q, after injecting a little more than half of it, it feels like a lot of pressure and sometimes pain. The first one into the fat of my abdomen made sure I don't go there anymore.

I now inject into the fat of my butt, but it's still uncomfortable. If I go deeper with a 27g 1/2", then no problem. Any ideas why this is?